Search results for " Ageing"
showing 10 items of 233 documents
Ethics of aging
2021
Abstract With a steady increase in the number of older people worldwide and a much higher percentage of older people as part of the overall population, we are on the verge of becoming a mass geriatric society. These gains in extra years are not only a prolongation of individual lives but also result in demographic transitions that will challenge economic, social, and geopolitical systems and chiefly our healthcare systems in many countries. Population aging calls for the reassessment of existing policies and programs, in order to ensure a fair distribution of rights, burdens, and responsibilities between generations and to give the opportunity to older people to live fully a phase of life t…
Workforce active ageing case study in a Romanian manufacturing company
2017
Ageing workforce is a major trend that characterizes the demographic evolution of Europe, which generally affects the society, but also the organizations from economic and social point of view. Employers should change their negative perceptions of ageing workforce, whereas the changes that occur along with ageing are unable to influence the efficiency of work, assuming that a suitable strategy implemented to prevent and manage potential problems. The paper includes European and national statistics on the issue, a case study analysing the workforce ageing management in a Romanian manufacturing company, which has succeeded in achieving the active ageing target, and - on this basis - several g…
Blood and skeletal muscle ageing determined by epigenetic clocks and their associations with physical activity and functioning
2021
AbstractThe aim of this study was to investigate the correspondence of different biological ageing estimates (i.e. epigenetic age) in blood and muscle tissue and their associations with physical activity (PA), physical function and body composition. Two independent cohorts (N = 139 and N = 47) were included, whose age span covered adulthood (23–69 years). Whole blood and m. vastus lateralis samples were collected, and DNA methylation was analysed. Four different DNA methylation age (DNAmAge) estimates were calculated using genome-wide methylation data and publicly available online tools. A novel muscle-specific methylation age was estimated using the R-package ‘MEAT’. PA was measured with q…
Stress reactivity elicits a tissue-specific reduction in telomere length in aging zebrafish (Danio rerio)
2020
ABSTRACTTelomere length reflects cellular ageing. Increased telomere shortening in leukocytes is associated with a range of neurodegenerative and cardiovascular diseases, the onset and progression of which may be mediated by behavioural traits such as anxiety and stress reactivity. However, the effects of the hypothalamus-pituitary-adrenal axis stress response are shown to be tissue specific. As such, leukocyte telomere length may not give an accurate measure of the relationship between stress-reactivity and telomere length in disease relevant tissues. To test the hypothesis that stress-reactivity contributes to age-related telomere shortening in a tissue specific manner, we examined the co…
Higher physical fitness levels are associated with less language decline in healthy ageing
2017
Healthy ageing is associated with decline in cognitive abilities such as language. Aerobic fitness has been shown to ameliorate decline in some cognitive domains, but the potential benefits for language have not been examined. In a cross-sectional sample, we investigated the relationship between aerobic fitness and tip-of-the-tongue states. These are among the most frequent cognitive failures in healthy older adults and occur when a speaker knows a word but is unable to produce it. We found that healthy older adults indeed experience more tip-of-the-tongue states than young adults. Importantly, higher aerobic fitness levels decrease the probability of experiencing tip-of-the-tongue states i…
Effect of Short-Term and UV Irradiation Aging on the Behaviour of SBS-Modified Bitumen
2022
To obtain road bitumen with improved temperature and fatigue resistance, polymers and/or rubbers could be added to it. A particularly suitable polymer for bitumen modification is styrene-butadiene-styrene (SBS) copolymer but limited information is available about the ageing behaviour of modified binders. In this work, two neat bitumens, with different penetration grades, and two SBS-modified bitumens, containing different SBS amounts, were selected, and their short-term and UVB ageing behaviour were investigated considering dynamic shear rheometry and Attenuated Total Reflectance-Fourier Transformation InfraRed spectroscopy (ATR-FTIR). Short-time ageing behaviour was investigated performing…
Study of a structural change in bitumen induced by the photooxidation aging method
A framework for remission in SLE
2017
ObjectivesTreat-to-target recommendations have identified ‘remission’ as a target in systemic lupus erythematosus (SLE), but recognise that there is no universally accepted definition for this. Therefore, we initiated a process to achieve consensus on potential definitions for remission in SLE.MethodsAn international task force of 60 specialists and patient representatives participated in preparatory exercises, a face-to-face meeting and follow-up electronic voting. The level for agreement was set at 90%.ResultsThe task force agreed on eight key statements regarding remission in SLE and three principles to guide the further development of remission definitions:1. Definitions of remission wi…
Evaluation of dietary patterns among men and women over 80 years of age living in a rural area of south-west Poland
2018
Background: Proper nutrition is an important factor in maintaining health and preventing disease development or progression regardless of age, but is especially relevant for elderly people. Seniors rarely follow nutritional and life-style guidelines, which may correlate with poor health, multiple morbidities, polypharmacy and premature death. Aim of the study: The aim of this study was to evaluate the nutritional pattern, food choices, knowledge about healthy eating, body mass and health issues among men and women over 80 years of age living in a rural area of south-west Poland. Material and methods: 100 participants, women and men, aged 79.6–93.3 years, responded to a questionnaire on nutr…
Gerontology is essential to the identity of geriatric medicine
2019
The concept of the preeminence of multidimensional func-tional status in health care, one of the first achievements of geriatric medicine, has been endorsed by diverse sources, and is now a cultural patrimony of medicine. One of the main goals of geriatric medicine is to allow older people to remain as independent as possible for as long as possible. The integrated research of geriatricians and gerontologists has been at the forefront of the development, testing, and application of tools to assess functional status, including activities of daily living, gait and mobility, cognition, psy-chological status, depression, and social support.