Search results for " Aggregation"

Oral Glycoprotein IIb/IIa Antagonists for Unstable Angina — Is There Still a Chance for the Oral Substances?

2001

The intravenous glycoprotein IIb/IIIa antagonists abciximab, tirofiban and eptifibatide are well accepted for the therapy of patients with unstable angina and/or as concomitant medication during coronary interventions. Despite the fact that these drugs are not used in all patients presenting with unstable angina during coronary interventions, the scientific evidence is overwhelming including the substantial reduction in mortality 3 years after utilisation of abciximab for coronary interventions in patients with unstable angina. In addition to these two indications, intravenous glycoprotein IIb/IIIa antagonists are currently being investigated for use in patients undergoing carotid artery in…

Sulfinpyrazone and platelet function in hypertensive patients

1984

A novel secure aggregation scheme for wireless sensor networks using stateful public key cryptography

2015

International audience; Wireless sensor networks (WSNs) are nowadays considered as an important part of the Internet of Things (IoT). In these networks, data aggregation plays an essential role in energy preservation. However, WSNs are usually deployed in hostile and unattended environments (e.g. military applications) in which the confidentiality and integrity security services are widely desired. Recently, homomorphic encryptions have been applied to conceal sensitive information during aggregation such that algebraic operations are done directly on ciphertexts without decryption. The main benefit is that they offer the end-to-end data confidentiality and they do not require expensive com…

Introduction and Technical Survey: Protein Aggregation and Fibrillogenesis

2012

In this chapter we provided the overall background to the subject of protein aggregation and fibrillogenesis in amyloidogenesis, with introduction and brief discussion of the various topics that are included with the coming chapters. The division of the book into basic science and clinical science sections enables correlation of the topics to be made. The many proteins and peptides that have currently been found to undergo fibrillogenesis are tabulated. A broad technical survey is made, to indicate the vast array of techniques currently available to study aspects of protein oligomerization, aggregation and fibrillogenesis. These are split into three groups and tabulated, as the microscopica…

ACCURATE DENSE STEREO MATCHING FOR ROAD SCENES

2017

International audience; Stereo matching task is the core of applications linked to the intelligent vehicles. In this paper, we present a new variant function of the Census Transform (CT) which is more robust against radiometric changes in real road scenes. We demonstrate that the proposed cost function outperforms the conventional cost functions using the KITTI benchmark. The cost aggregation method is also updated for taking into account the edge information. This enables to improve significantly the aggregated costs especially within homogenous regions. The Winner-Takes-All (WTA) strategy is used to compute disparity values. To further eliminate the remainder matching ambiguities , a post…

A New Platform for Automatic Bottom-Up Electric Load Aggregation

2017

In this paper, a new virtual framework for load aggregation in the context of the liberalized energy market is proposed. Since aggregation is managed automatically through a dedicated platform, the purchase of energy can be carried out without intermediation as it happens in peer-to-peer energy transaction models. Differently from what was done before, in this new framework, individual customers can join a load aggregation program through the proposed aggregation platform. Through the platform, their features are evaluated and they are clustered according to their reliability and to the width of range of regulation allowed. The simulations show the deployment of an effective clustering and …

Copper(II) and zinc(II) interaction with AB42: effects of metal binding on peptide’s aggregation rate and morphology of the aggregates.

2011

Defining Kawasaki disease and pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection during SARS-CoV-2 epidemic in…

2021

Abstract Background There is mounting evidence on the existence of a Pediatric Inflammatory Multisystem Syndrome-temporally associated to SARS-CoV-2 infection (PIMS-TS), sharing similarities with Kawasaki Disease (KD). The main outcome of the study were to better characterize the clinical features and the treatment response of PIMS-TS and to explore its relationship with KD determining whether KD and PIMS are two distinct entities. Methods The Rheumatology Study Group of the Italian Pediatric Society launched a survey to enroll patients diagnosed with KD (Kawasaki Disease Group – KDG) or KD-like (Kawacovid Group - KCG) disease between February 1st 2020, and May 31st 2020. Demographic, clini…

Application of Cell Culture for the Production of Bioactive Compounds from Sponges:  Synthesis of Avarol by Primmorphs from Dysidea avara

2000

Among all metazoan phyla, sponges are known to produce the largest number of bioactive compounds. However, until now, only one compound, arabinofuranosyladenine, has been approved for application in humans. One major obstacle is the limited availability of larger quantities of defined sponge starting material. Recently, we introduced the in vitro culture of primmorphs from Suberites domuncula, which contain proliferating cells. Now we have established the primmorph culture also from the marine sponge Dysidea avara and demonstrate that this special form of sponge cell aggregates produces avarol, a sesquiterpenoid hydroquinone, known to display strong cytostatic activity especially against ma…

Automatic Counting of Intra-Cellular Ribonucleo-Protein Aggregates in Saccharomyces cerevisiae Using a Textural Approach.

2019

AbstractIn the context of microbiology, recent studies show the importance of ribonucleo-protein aggregates (RNPs) for the understanding of mechanisms involved in cell responses to specific environmental conditions. The assembly and disassembly of aggregates is a dynamic process, the characterization of the stage of their evolution can be performed by the evaluation of their number. The aim of this study is to propose a method to automatically determine the count of RNPs. We show that the determination of a precise count is an issue by itself and hence, we propose three textural approaches: a classical point of view using Haralick features, a frequency point of view with generalized Fourier…