Search results for " Allocation"
showing 10 items of 502 documents
AI for Resource Allocation and Resource Allocation for AI: a two-fold paradigm at the network edge
2022
5G-and-beyond and Internet of Things (IoT) technologies are pushing a shift from the classic cloud-centric view of the network to a new edge-centric vision. In such a perspective, the computation, communication and storage resources are moved closer to the user, to the benefit of network responsiveness/latency, and of an improved context-awareness, that is, the ability to tailor the network services to the live user's experience. However, these improvements do not come for free: edge networks are highly constrained, and do not match the resource abundance of their cloud counterparts. In such a perspective, the proper management of the few available resources is of crucial importance to impr…
Imiquimod-Induced Psoriasis in Mice Depends on the IL-17 Signaling of Keratinocytes
2018
The pathology of psoriasis strongly depends on IL-17A. Monoclonal antibodies blocking either the cytokine or its receptor are among the most efficient treatments for psoriatic patients. Keratinocytes can be activated upon exposure to IL-17A and tumor necrosis factor-α and secrete secondary cytokines and chemokines in the inflamed skin. In psoriasis and its imiquimod-induced mouse model, a strong skin infiltration of neutrophils and inflammatory monocytes can be observed. However, to date, it is not clear how exactly those cellular populations are attracted to the skin and how they contribute to the pathogenesis of the disease. To define the crucial cell type responding to IL-17 and initiati…
Spectrum utilization over licensed and unlicensed bands
2016
Nowadays, telecommunication technology becomes one of the universal phenomenon used in people’s daily life. In recent years, the appearance of smartphones, tab lets, mobile Internet Apps and services led to mobile data traffic proliferating, and the devices and ser- vices will continue to increase dramatically for some time. The fact along with the tele- communication devices increasing to aggravate the overload problem is that the users seek for fast and reliable data transmission, as well as service continuity. To address the over- load issue, LTE-Unlicensed (LTE-U) turns out to be one of the reasonable solutions to provide high performance and seamless interoperability for users’ experie…
Cutaneous RANK-RANKL Signaling Upregulates CD8-Mediated Antiviral Immunity during Herpes simplex Virus Infection by Preventing Virus-Induced Langerha…
2015
Herpes simplex virus-type 1 (HSV-1) causes the majority of cutaneous viral infections. Viral infections are controlled by the immune system, and CD8(+) cytotoxic T-lymphocytes (CTLs) have been shown to be crucial during the clearance of HSV-1 infections. Although epidermal Langerhans cells (LCs) are the first dendritic cells (DCs) to come into contact with the virus, it has been shown that the processing of viral antigens and the differentiation of antiviral CTLs are mediated by migratory CD103+ dermal DCs and CD8 alpha(+) lymph node resident DCs. In vivo regulatory T-cells (Tregs) are implicated in the regulation of antiviral immunity and we have shown that signaling via the receptor activ…
Housing conditions modulate the reinforcing properties of cocaine in adolescent mice that binge on fat
2017
Abstract Binge eating is a specific form of overeating characterized by intermittent, excessive eating. To date, several studies have addressed the effects that bingeing on fat has on the rewarding effects of drugs of abuse, but they have found contradictory and highly variable results. Housing conditions could modulate these results, as most studies employ isolated animals to measure the exact amount of food that is ingested. The aim of this study was to evaluate the effects of housing conditions on the response of mice to cocaine, modulated by bingeing on a high-fat diet during adolescence. After 40 days of binge-eating for 2 h, three days a week (PND 29–69), the reinforcing effects of a …
Efficacy of intra-arterial lidocaine infusion in the treatment of cerulein-induced acute pancreatitis
2020
Background Disturbances in pancreatic microcirculation, beginning with vasoconstriction, are crucial in early pancreatitis and progression to necrotizing pancreatitis. Thus, vascular-targeted treatment aiming to restore a sufficient level of microcirculation through vasodilation would possibly reduce the severity of pancreatitis. Lidocaine is an anti-arrhythmic and local anesthetic drug, which also acts as a vasodilator at higher concentrations. Objectives To evaluate the efficacy of intra-arterial infusion of lidocaine into the celiac trunk in treatment of cerulein-induced acute pancreatitis. Material and methods Wistar rats (n = 20) were randomly divided into 2 equal groups: the control g…
A trade-off between current and future sex allocation revealed by maternal energy budget in a small mammal.
2011
Sex-allocation theories generally assume differential fitness costs of raising sons and daughters. Yet, experimental confirmation of such costs is scarce and potential mechanisms are rarely addressed. While the most universal measure of physiological costs is energy expenditure, only one study has related the maternal energy budget to experimentally controlled offspring sex. Here, we experimentally test this in the bank vole (Myodes glareolus) by simultaneously manipulating the litter's size and sex ratio immediately after birth. Two weeks after manipulation, when mothers were at the peak of lactation and were pregnant with concurrent litters, we assessed their energy budget. We found that …
Sex–biased maternal investment in voles: importance of environmental conditions
2004
Adaptive bias in sex allocation is traditionally proposed to be related to the condition of mothers as well as to the unequal fitness values of produced sexes. A positive relationship between mother condition and investment into male offspring is often predicted. This relationship was also recently found to depend on environmental conditions. We studied these causalities experimentally using a design where winter food supply was manipulated in eight outdoor-enclosed populations of field voles Microtus agrestis. At the beginning of the breeding season in spring, food-supplemented mothers seemed to be in a similar condition, measured as body mass, head width, body condition index and parasite…
Dynamic Resource Allocation and Computation Offloading for Edge Computing System
2020
In this work, we propose a dynamic optimization scheme for an edge computing system with multiple users, where the radio and computational resources, and offloading decisions, can be dynamically allocated with the variation of computation demands, radio channels and the computation resources. Specifically, with the objective to minimize the energy consumption of the considered system, we propose a joint computation offloading, radio and computational resource allocation algorithm based on Lyapunov optimization. Through minimizing the derived upper bound of the Lyapunov drift-plus-penalty function, the main problem is divided into several sub-problems at each time slot and are addressed sepa…
Energy Harvesting Enabled Energy Efficient Cognitive Machine-to-Machine Communications
2020
Energy harvesting based cognitive machine-to-machine (EH-CM2M) communication has been introduced to overcome the problem of spectrum scarcity and limited battery capacity by enabling M2M transmitters (M2M-TXs) to harvest energy from ambient radio frequency signals, as well as to reuse the resource blocks (RBs) allocated to CUs in an opportunistic manner. However, the complex interference scenarios and the stringent QoS requirements pose new challenges on resource allocation optimization. In this chapter, we consider how to maximize the energy efficiency of M2M-TXs via the joint optimization of channel selection, peer discovery, power control, and time allocation.