Search results for " Atri"

Study on the histamine-like activity of guanfacine

1990

Abstract The effects of guanfacine have been studied on guinea-pig isolated atria and diethylstilboestrol-treated rat isolated uterus to determine whether it possesses histamine-like activity. Guanfacine produced a concentration-dependent negative chronotropic effect which was not modified by ranitidine (0.1 μM). In rat isolated uterus contracted by KCl, clonidine (5–5000 μM) produced concentration-dependent relaxation which was blocked by ranitidine (0.1 μM), but guanfacine only produced relaxation at high concentrations (100–1000 μM), and this was not affected by ranitidine (0.1 μM). It is concluded that guanfacine, unlike clonidine, does not produce effects due to activation of H2-recept…

Comparison of Nonclassic and Classic Phenotype of Hypertrophic Cardiomyopathy Focused on Prognostic Cardiac Magnetic Resonance Parameters: A Single-C…

2022

Patients with nonclassic phenotypes (NCP)—more advanced stages of hypertrophic cardiomyopathy (HCM)—constitute an intriguing and heterogeneous group that is difficult to diagnose, risk-stratify, and treat, and often neglected in research projects. We aimed to compare cardiac magnetic resonance (CMR) parameters in NCP versus classic phenotypes (CP) of HCM with special emphasis given to the parameters of established and potential prognostic importance, including numerous variables not used in everyday clinical practice. The CMR studies of 88 patients performed from 2011 to 2019 were postprocessed according to the study protocol to obtain standard and non-standard parameters. In NCP, the late …

Atrial activity extraction for atrial fibrillation analysis using blind source separation.

2004

This contribution addresses the extraction of atrial activity (AA) from real electrocardiogram (ECG) recordings of atrial fibrillation (AF). We show the appropriateness of independent component analysis (ICA) to tackle this biomedical challenge when regarded as a blind source separation (BSS) problem. ICA is a statistical tool able to reconstruct the unobservable independent sources of bioelectric activity which generate, through instantaneous linear mixing, a measurable set of signals. The three key hypothesis that make ICA applicable in the present scenario are discussed and validated: 1) AA and ventricular activity (VA) are generated by sources of independent bioelectric activity; 2) AA …

Interpretation of epicardial mapping by means of computer simulations: Applications to calcium, lidocaine and to BRL 34915

1992

The aim of this work was to compare experimental investigations on effects of lidocaine, calcium and, BRL 34915 on reentries to simulated data obtained by use of a model of propagation based on the Huygens' construction method already described in previous works. Calcium and lidocaine effects are investigated on anisotropic conduction conditions. In both cases, reduction in conduction velocities are observed. In lidocaine case, a refractory area is located along the longitudinal axis. In agreement with experimental electrical mapping, the simulations show that the stabilization of reentrant excitation is mainly due to the existence of this refractory area around which the reentrant circuit …

Insular stock identification of <EM>Serranus atricauda</EM> (Pisces: Serranidae) through the presence of <EM>Ceratothoa steindachne…

2004

Ceratothoa steindachneri (Isopoda: Cymothoidae) and Pentacapsula cutanea (Myxozoa: Pentacapsulidae) parasites infecting the blacktail-comber ( Serranus atricauda ) were considered suitable as biological tags for stock identification around the islands of La Palma and Gran Canaria, in the Western and Eastern areas of the Canarian archipelago, respectively. The ecological parameters of both species differed significantly between the islands. While individuals caught off La Palma showed a high degree of infection by the isopod, a single infected fish was found off Gran Canaria. Also, the myxozoans showed a high level of infection on fish from Gran Canaria but it was reported on only a single s…

Paradoxical embolism after a femoral fracture

1998

The foramen ovale is anatomically open in 25 % of individuals, but functionally closed by the higher pressure in the left antrum. Right-to-left shunt and subsequent paradoxical embolism may occur when pressure in the left antrum rises, for example, as a result of pulmonary embolism. In the present case we demonstrate a patient who presented 20 days after osteosynthetic treatment of a femoral fracture with word-finding deficits. Cerebral MRT revealed a fresh ischemic insult. Duplex ultrasound of the legs showed a fresh thrombosis of the superficial femoral vein and scintigraphy of the lungs detected pulmonary embolism. Transesophageal contrast echocardiography trapped a hemodynamically spont…

Protecting against sedentary lifestyle, left atrial enlargement and atrial fibrillation.

2022

Estimación de la mortalidad atribuible a enfermedades laborales en España, 2004

2007

Ana M. García García (anagar@uv.es) El registro de enfermedades profesionales en España resulta insuficiente para valorar el impacto de las enfermedades de origen laboral en nuestro país. En el presente estudio se estima la mortalidad por enfermedades laborales y sus costes en base a riesgos atribuibles estimados en la literatura internacional.Métodos: Se aplican estimaciones de riesgo atribuible para la mortalidad de origen laboral calculadas por Nurminen y Karjalainen (Finlandia, 2001) al total de muertes por las enfermedades y grupos de edad relevantes en España y por comunidades autónomas en 2004. Se calculan los años potenciales de vida y de vida laboral perdidos. A partir de estos últ…

F. Dostojevskis un N. Gogolis (garstāsti «Saimniece» un «Briesmīgā atriebība»).

2022

Darbs veltīts fantastisku motīvu meklēšanai, kas apvieno F. Dostojevska stāstu “saimniece” un N. Gogoļa “briesmīgā atriebība”. Darba mērķis ir izsekot, kā F. Dostojevska darbos tiek īstenota rakstnieku radošā pēctece: “Saimniece” un “Briesmīgā atriebība” N.Gogoļa. Atklāt mistiskos motīvus. Autors veic abu redakciju pretstatīšanas analīzi, izmantojot informācijas apkopošanu. Darbs tiek sadalīts divās daļās. Pirmajā tiek izklāstīti galvenie teorētiskie jautājumi, kuri nepieciešami pētījuma veikšanai, otrajā daļā, savukārt, saistībā ar uzstādītajiem uzdevumiem. Šis pētījums rada interesi to filologu literatūras zinātnieku vidū, kuri ir ieinteresēti rakstniekam daiļrades, kā arī fantastisku mot…

Silent and symptomatic atrial fibrillation,during the acute phase of myocardial infarction : determinants and role of arginine methylated and oxidati…

2015

Atrial fibrillation (AF) is a frequent complication of acute myocardial infarction (AMI) with a poorer prognosis. Silent atrial fibrillation has been suggested to be frequent after AMI. However, most part of the studies has targeted only paroxysmal or persistent AF. Thus, Reduced Nitric Oxide availability and endothelial dysfunction has been recently recognized as a possible contributor to altered prognosis in AF. Asymmetric dimethylarginine (ADMA) can inhibit nitric oxide synthase and leads to endothelial dysfunction, inflammation and oxidative stress in multiple cardiovascular diseases. However, any study has addressed the relationship between ADMA levels and the occurrence of AF in AMI.W…