Search results for " BIOMEDICAL"

Transfer Entropy Analysis of Pulse Arrival Time - Heart Period Interactions during Physiological Stress

2022

Although Heart Period (HP) variability is the most widely used measure to assess cardiovascular oscillations, its evaluation combined with that of Pulse Arrival Time (PAT) variability may provide additional information about cardiac dynamics and cardiovascular interactions. In this study, we computed the transfer entropy from PAT to HP in 76 subjects monitored at rest and during orthostatic and mental stress using both a model-free (k- Nearest Neighbors) and a linear parametric estimator. Our results show how the information flow between these two variables depends on the physiological condition and how the nonlinear measure captures more information than the linear one during orthostatic s…

Euromediterranean Biomedical Journal: the renewed journal of young doctors aims even higher.

2014

In January 2006, a new journal, Capsula Eburnea, was born in the Italian scientific pub-lishing scene, with the initial goal of creating, at the same time, “an open scientific forum and a blog”. Until December 2009, the vast majority of manuscripts was still published in Italian, restricting the number of readers. From the end of 2009, the journal has undergone extensive changes, becoming indexed in the main scientific search engines (Scopus, Directory of Open Access Journal, Google Scholar, Ulrich Periodical Directory), and renewing its Editorial Team with a role reassign-ment and expanding the Editorial Board to up to 40 young doctors with proven scientific experience from 15 countries ar…

Effects of asymmetrical exercise demands on the symmetry of skin temperature in archers

2020

Abstract Objective: To analyse skin temperature asymmetries in response to asymmetrical exercise demand in archers. Approach: The skin temperature of the trunk and upper limbs was measured in 30 archers with an infrared camera at three different moments: before (Pre), immediately after (Post), and 10 min after (Post10) a simulated competition (18 warm-up shots and 72 qualifying round shots). Relative and absolute asymmetries were determined. Stepwise multiple linear regressions were performed using the variations of relative and absolute skin temperature asymmetries as predicting variables, and sex, age, experience, body mass index, bow mass, bow power, and rate of perceived exertion of com…

Evaluation of Risk Parameters in Bone Regeneration Using a Customized Titanium Mesh

2019

PURPOSE The aim of the study was an evaluation of risk factors for an innovative bone regeneration technique using a customized titanium mesh that was tested in a clinical setting. MATERIALS AND METHODS This retrospective study included 65 patients with 70 grafting procedures of osseous defects of the jaws with a customized titanium mesh together with Advanced- and Injectable-Platelet-Rich Fibrin (A- and I-PRF), resorbable membranes, and bone grafting materials. Exposures of the meshes and grafting outcome were analyzed according to a novel classification as (a) punctual and (b) tooth width or complete exposure of the mesh (c). No exposure was stated as (d). RESULTS In 37% of cases, exposur…

Praksisstudienes omfang og organisering i bioingeniørutdanningen

2022

Since 2005, scope and content of the biomedical laboratory scientist education have been defined by national guidelines to ensure equal final competence for all candidates. From 2019, a new regulation on national guidelines was approved. Both new and old guidelines have regulated the learning outcomes and scope of practice in education. In this study, the scope and organization of the practical studies at the various study programs are characterized, in order to investigate differences and similarities and to facilitate that the study programs can learn from each other. Data has been obtained from each study program for the scope and organization of supervised internal practice, external pr…

Overcoming the barrier of CD8+ T cells: Two types of nano-sized carriers for siRNA transport

2019

Abstract Bioengineering immune cells via gene therapy offers treatment opportunities for currently fatal viral infections. Also cell therapeutics offer most recently a breakthrough technology to combat cancer. These primary human cells, however, are sensitive to toxic influences, which make the utilization of optimized physical transfection techniques necessary. The otherwise commonly applied delivery agents such as LipofectamineⓇ or strongly cationic polymer structures are not only unsuitable for in vivo experiments, but are also highly toxic to immune cells. This study aimed to improve the design of polymeric carrier systems for small interfering RNA, which would allow efficient internali…

2018

Electrocardiographic imaging (ECGI) strongly relies on a priori assumptions and additional information to overcome ill-posedness. The major challenge of obtaining good reconstructions consists in finding ways to add information that effectively restricts the solution space without violating properties of the sought solution. In this work, we attempt to address this problem by constructing a spatio-temporal basis of body surface potentials (BSP) from simulations of many focal excitations. Measured BSPs are projected onto this basis and reconstructions are expressed as linear combinations of corresponding transmembrane voltage (TMV) basis vectors. The novel method was applied to simulations o…

In vitroandin vivoenhancement of osteogenic capacity in a synthetic BMP-2 derived peptide-coated mineralized collagen composite

2013

Enhancement of osteogenic capacity was achieved in a mineralized collagen composite, nano-hydroxyapatite/collagen (nHAC), by loading with synthetic peptides derived from BMP-2 residues 32-48 (P17-BMP-2). Rabbit marrow stromal cells (MSCs) were used in vitro to study cell biocompatibility, attachment and differentiation on the mineralized collagen composite by a cell counting kit, scanning electron microscopy (SEM) and real-time reversed transcriptase-polymerase chain reaction analysis (RT-PCR). Optimal peptide dosage (1.0 µg/mL) was obtained by RT-PCR analysis in vitro. In addition, the relative expression level of OPN and OCN was significantly upregulated on P17-BMP-2/nHAC compared with nH…

Photocrosslinkable polysaccharide hydrogel composites based on dextran or pullulan-amylose blends with cytokines for a human co-culture model of huma…

2016

Although a large body of research has been devoted to biomaterial development for bone tissue engineering and related medical disciplines in the last few years, novel and optimized materials especially for bone fractures of critical sizes demand continued development. In this respect, polysaccharide-based hydrogels demonstrate beneficial properties and fulfill the main requirements for a bone tissue scaffold as they are hydrophilic, biocompatible, and biodegradable. The aim of the present study was the development of a natural polysaccharide-based scaffold material that can integrate with the host tissue and support bone regeneration. For this purpose, we prepared and investigated two polym…

Effect of proanthocyanidin mediated immediate and delayed dentin sealing on the strength of premolars restored with composite resin inlay.

2019

Background Immediate dentin sealing (IDS) with proanthocyanidin (PA) could be used before cementation with a self-adhesive (SA) cement. The aim of this study was to assess the effect of PA treatment on acid-etched dentin before adhesive application, in IDS and delayed dentin sealing (DDS), on the strengthening property of SA-cemented composite resin inlay in premolars. Material and Methods Eighty-four maxillary premolars were divided into 7 groups (n=12): 1) (Intact) Sound teeth served as controls; groups 2-7) After cavity preparation and fabrication of composite resin inlay, temporary inlays were made and cemented. After one week, the inlays were removed and composite inlays were luted wit…