Search results for " BIOMEDICAL"
showing 10 items of 480 documents
Radiation engineered nanogels as platforms for medical diagnostics and therapeutic nanodevices
2015
A scalable, single step, synthetic approach for the manufacture of biocompatible, functionalized microgels and nanogels has been developed. Pulsed EB irradiation of PVP aqueous solutions, at relatively low energies per pulse and doses within the sterilization dose range, has led to a variety of ‘as-born’ sterile, functional nanostructures that exhibit a combination of favourable properties which make them suitable as biomedical nanocarriers. Reactive functional groups have been generated by graft copolymerization of functional acrylic monomers. These groups can be used to attach fluorescent probes to the NPs, to bioconjugate ligands of specific cell receptors and to incorporate therapeutics…
Medicine of the future: How and who is going to treat us?
2023
Medicine’s ability to quickly respond to challenges raises questions from researchers, practitioners, and society as a whole. Our task in this study was to identify key and atypical current factors influencing the development of medicine and to predict the development of medicine in the short, medium, and long term. To implement our study, we selected 22 medical experts and applied the three-level Delphi method. The current trends caused by COVID-19 have a short-term impact, but they will launch other drivers that will transform the healthcare industry. Well-being technologies, data-informed personalization, and climate change will become key drivers for the development of medicine over the…
Translating recent results from the Cardiovascular Outcomes Trials into clinical practice: recommendations from the Central and Eastern European Diab…
2017
Aims These recommendations aim to improve care for patients with type 2 diabetes (T2D) at high cardiovascular (CV) risk in Central and Eastern Europe. Cardiovascular disease (CVD) and/or chronic kidney disease (CKD) are major interdependent comorbidities in patients with T2D, accounting for 50% of mortality. Following recent CV outcomes trial (CVOT) results, including those from EMPA-REG OUTCOME®, LEADER®, SUSTAIN™-6 and, most recently, the CANVAS study, it is essential to develop regional expert consensus recommendations to aid physicians in interpreting these newest data to clinical practice. Methods The Central and Eastern European Diabetes Expert Group (CEEDEG) followed a Delphi method …
Immunosenescence and Cytomegalovirus
2010
Since Looney at al. published their seminal paper a decade ago [1] it has become clear that many of the differences in T cell immunological parameters observed between young and old people are related to the age-associated increasing prevalence of infection with the persistent β-herpesvirus HHV-5 (Cytomegalovirus). Ten years later, studies suggest that hallmark age-associated changes in peripheral blood T cell subset distribution may not occur at all in people who are not infected with this virus [[2]; Derhovanessian et al., in press]. Whether the observed changes are actually caused by CMV is an open question, but very similar, rapid changes observed in uninfected patients receiving CMV-in…
Loss Aversion and Risk Aversion in Non-Clinical Negative Symptoms and Hypomania
2020
In the field of behavioral decision-making, “loss aversion” is a behavioral phenomenon in which individuals show a higher sensitivity to potential losses than to gains. Conversely, “risk averse” individuals have an enhanced sensitivity/aversion to options with uncertain consequences. Here we examine whether hypomania or negative symptoms predict the degree of these choice biases. We chose to study these two symptom dimensions because they present a common theme across many syndromes with compromised decision-making. In our exploratory study, we employed a non-clinical sample to dissociate the hypomanic from negative symptom dimension regarding choice behavior. We randomly selected a sample …
Automatic Processing of Changes in Facial Emotions in Dysphoria: A Magnetoencephalography Study
2018
It is not known to what extent the automatic encoding and change detection of peripherally presented facial emotion is altered in dysphoria. The negative bias in automatic face processing in particular has rarely been studied. We used magnetoencephalography (MEG) to record automatic brain responses to happy and sad faces in dysphoric (Beck’s Depression Inventory ≥ 13) and control participants. Stimuli were presented in a passive oddball condition, which allowed potential negative bias in dysphoria at different stages of face processing (M100, M170, and M300) and alterations of change detection (visual mismatch negativity, vMMN) to be investigated. The magnetic counterpart of the vMMN was el…
EUROMEDITERRANEAN BIOMEDICAL JOURNAL: THE RENEWED MANUSCRIPT LAYOUT AND WEB RENDERING FORESHADOW FURTHER JOURNAL IMPROVEMENT.
2017
In January 2006, a new journal, Capsula Eburnea, was born into the Italian scientific publishing scene with the initial goal of creating, at the same time, “an open scientific forum and a blog”, based on the premise that “in medicine, nothing should be considered stable, immutable or unsusceptible to critical review at any time, by any scientist”. The Editorial Team progressively sought to improve the quality of the manuscripts published, introducing the requirement for all articles to be written in English, and changed the Journal’s name to EuroMediterranean Biomedical Journal in 2012. Over the last five years, approximately 125 articles by young doctors (including original articles, revie…
A Novel Bio-Inspired Approach for High-Performance Management in Service-Oriented Networks
2021
Service-continuity in distributed computing can be enhanced by designing self-organized systems, with a non-fixed structure, able to modify their structure and organization, as well as adaptively react to internal and external environment changes. In this paper, an architecture exploiting a bio-inspired management approach, i.e., the functioning of cell metabolism, for specialized computing environments in Service-Oriented Networks (SONs) is proposed. Similar to the processes acting in metabolic networks, the nodes communicate to each other by means of stimulation or suppression chains giving rise to emergent behaviors to defend against foreign invaders, attacks, and malfunctioning. The mai…
Truncation effects on muscular fatigue indexes based on M waves analysis
2012
International audience; In this paper, we investigate muscular fatigue. We propose a new fatigue index based on the continuous wavelet transform (CWT) and compare it with the standard fatigue indexes from literature. Fatigue indexes are all based on the electrical activity of muscles (electromyogram) acquired during an electrically stimulated contraction (ES). The stimulator and electromyogram system, which were presented in a previous work, allows real-time analysis. The extracted fatigue parameters are compared between each other and their sensitivity to noise is studied. The effect of truncation of M waves is then investigated, enlightening the robustness of the index obtained using CWT.
Multi axis representation and Euclidean distance of muscle fatigue indexes during evoked contractions
2014
International audience; In this article, we proposed a new representation of muscular fatigue during evoked muscle contractions based on fatigue indexes such as peak to peak amplitude, RMS of the M wave, mean and median frequency and fatigue index calculated from continuous wavelet transform (I CWT). These new representations of muscle fatigue using multi axis represented and Euclidean distance give better insights on changes in physiological characteristics during muscle fatigue. This technique provides a fatigue index using several muscle characteristics. The use of other kinds of fatigue characteristics as force could also be possible.