Search results for " Basic"
showing 10 items of 10515 documents
Retallades en l'estat del benestar i burnout
2013
The current recession and economic crisis of capital that is taking place throughout Europe, as well as the antisocial measures that accompany it, are causing the extinction in the short and medium term of the so-called Welfare State, at a different speed in every EU Member State. We are professionals of the social sphere and we are used to work with usual and recent victims of such crisis. However, this time we are victims too as a consequence of the cutbacks, privatization processes and elimination of benefits and services that are being put into practice. As Social Workers we should consider to take action from the teaching, professional practice and scientific thought fronts in order to…
Importancia del Trabajo Social como forma de intervención municipal
2011
Trascurridos 30 años de la puesta en marcha del Sistema Público de Servicios Sociales, procede destacar el protagonismo desarrollado por los ayuntamientos que han sido el referente más significativo de la implantación del Sistema por su compromiso institucional en el desarrollo de los Servicios Sociales Generales Básicos, potenciando las Unidades de Trabajo Social en todos los municipios, lo que ha hecho visible para la ciudadanía, tanto las potencialidades de los Servicios Sociales, como sus déficits. Hoy se puede afirmar que las/los ciudadanas/os reclaman de los Servicios Sociales el mismo enfoque que perciben la Sanidad o la Educación, como pilares del Estado de Bienestar y se exige que …
Datu izmaiņu pārlūkošanas moduļa izstrāde nekustamā īpašuma nodokļa administrēšanas sistēmai NINO
2018
Darbā aprakstīta izstrādes gaita nekustamā īpašuma nodokļa administrēšanas sistēmas NINO papildinājuma – datu izmaiņu pārlūkošanas moduļa - risinājumam. Tas paredzēts NINO lietotājiem ērtākai un savām vajadzībām pielāgojamai datu izmaiņu vēstures pārlūkošanai. Risinājums atvieglo gan Latvijas pašvaldību nodokļu inspektoru darbu, gan šo darbinieku kontroli ar datu izmaiņām saistītos jautājumos, kā arī samazina nepieciešamību griezties pēc palīdzības pie NINO klientu konsultantiem. Datu izmaiņu vēsturi iespējams attēlot uz ekrāna vai izklājlapu lietotnē Microsoft Excel, saņemot informāciju, kāds lietotājs, kad un kā izmainījis konkrēta NINO objekta datus. Programmprodukta izstrāde veikta, iev…
Methylophilaceae and Hyphomicrobium as target taxonomic groups in monitoring the function of methanol-fed denitrification biofilters in municipal was…
2017
Abstract Molecular monitoring of bacterial communities can explain and predict the stability of bioprocesses in varying physicochemical conditions. To study methanol-fed denitrification biofilters of municipal wastewater treatment plants, bacterial communities of two full-scale biofilters were compared through fingerprinting and sequencing of the 16S rRNA genes. Additionally, 16S rRNA gene fingerprinting was used for 10-week temporal monitoring of the bacterial community in one of the biofilters. Combining the data with previous study results, the family Methylophilaceae and genus Hyphomicrobium were determined as suitable target groups for monitoring. An increase in the relative abundance …
Microbial Community Response on Wastewater Discharge in Boreal Lake Sediments
2017
Despite high performance, municipal wastewater treatment plants (WWTPs) still discharge significant amounts of organic material and nitrogen and even microbes into the receiving water bodies, altering physico-chemical conditions and microbial functions. In this study, we examined how nitrified wastewater affects the microbiology of boreal lake sediments. Microbial community compositions were assessed with next generation sequencing of the 16S rRNA gene, and a more detailed view on nitrogen transformation processes was gained with qPCR targeting on functional genes (nirS, nirK, nosZI, nosZII, amoAarchaea, and amoAbacteria). In both of the two studied lake sites, the microbial community compo…
Management of metabolic adverse events of targeted therapies and immune checkpoint inhibitors in cancer patients: an Associazione Italiana Oncologia …
2020
The growing insights in the next-generation immunotherapy and the state-of-the-art advancement in targeted-agents significantly improved clinical outcome of cancer patients by pointing towards a unexplored Achilles' heel. Novel toxicity profiles have been uncovered, representing unmet medical needs. Thus, a panel of expert provide comprehensive pharmacological and clinical evidence, to provide a patient-tailored approach to metabolic adverse events associated with novel anti-cancer treatments. Prompted by the need of a multidisciplinary cooperation, a working group of Associazione Italiana Oncologia Medica (AIOM), Associazione Medici Diabetologi (AMD) and Societa Italiana Farmacologia (SIF)…
Face mask use in the Community for Reducing the Spread of COVID-19: a systematic review
2021
ABSTRACTBackgroundEvidence is needed on the effectiveness of wearing face masks in the community to prevent SARS-CoV-2 transmission.MethodsSystematic review and meta-analysis to investigate the efficacy and effectiveness of face mask use in a community setting and to predict the effectiveness of wearing a mask. We searched MEDLINE, EMBASE, SCISEARCH, The Cochrane Library and pre-prints from inception to 22 April 2020 without restriction by language. We rated the certainty of evidence according to Cochrane and GRADE approach.FindingsOur search identified 35 studies, including 3 randomised controlled trials (RCTs) (4017 patients), 10 comparative studies (18984 patients), 13 predictive models,…
Examinations of Bilateral Epileptiform Activities in Hippocampal Slices Obtained From Young Mice
2021
Bilateral interconnections through the hippocampal commissure play important roles in synchronizing or spreading hippocampal seizure activities. Intact hippocampi or bilateral hippocampal slices have been isolated from neonatal or immature rats (6–7 or 12–21 days old, respectively) and the mechanisms underlying the bilateral synchrony of hippocampal epileptiform activities have been investigated. However, the feasibility of examining bilateral epileptiform activities of more developed hippocampal circuitryin vitroremains to be explored. For this, we prepared bilateral hippocampal slices from C57 black mice, a strain commonly used in neuroscience and for genetic/molecular modifications. Youn…
Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infect…
2017
Invasive pulmonary aspergillosis (IPA) is a life-threatening lung disease of hematological malignancy or bone marrow transplant patients caused by the ubiquitous environmental fungus Aspergillus fumigatus. Current diagnostic tests for the disease lack sensitivity as well as specificity, and culture of the fungus from invasive lung biopsy, considered the gold standard for IPA detection, is slow and often not possible in critically ill patients. In a previous study, we reported the development of a novel non-invasive procedure for IPA diagnosis based on antibody-guided positron emission tomography and magnetic resonance imaging (immunoPET/MRI) using a [64Cu] DOTA-labeled mouse monoclonal anti…
Photoactive Yellow Protein Chromophore Photoisomerizes around a Single Bond if the Double Bond Is Locked
2020
Photoactivation in the Photoactive Yellow Protein, a bacterial blue light photoreceptor, proceeds via photo-isomerization of the double C=C bond in the covalently attached chromophore. Quantum chemistry calculations, however, have suggested that in addition to double bond photo-isomerization, the isolated chromophore and many of its analogues, can isomerize around a single C-C bond as well. Whereas double bond photo-isomerization has been observed with x-ray crystallography, experimental evidence for single bond photo-isomerization is currently lacking. Therefore, we have synthesized a chromophore analogue, in which the formal double bond is covalently locked in a cyclopentenone ring and ca…