Search results for " Bioreactor"
showing 10 items of 149 documents
A dynamic air–liquid interface system for in vitro mimicking of the nasal mucosa
2022
The development of an in vitro 3D model for the growth of the nasal mucosa cells can improve the therapy and the study of pathological states for subjects with chronic airway conditions. We have previously characterized a system consisting of a scaffold with an internal channel and a perfusion bioreactor with two independent flows provided by an external and an internal circuit, respectively. In this paper, this system was designed as a model of the nasal cavity, in which cells, grown on the inner surface of the scaffold channel, would be in contact at the same time with both culture medium, supplied by the external circuit, and air, provided with the internal flow. To ensure adequate nutri…
Widening the applicability of AnMBR for urban wastewater treatment through PDMS membranes for dissolved methane capture: Effect of temperature and hy…
2021
[EN] AnMBR technology is a promising alternative to achieve future energy-efficiency and environmental-friendly urban wastewater (UWW) treatment. However, the large amount of dissolved methane lost in the effluent represents a potential high environmental impact that hinder the feasibility of this technology for full-scale applications. The use of degassing membranes (DM) to capture the dissolved methane from AnMBR effluents can be considered as an interesting alternative to solve this problem although further research is required to assess the suitability of this emerging technology. The aim of this study was to assess the effect of operating temperature and hydrodynamics on the capture of…
Photocatalytic ozonation under visible light for the remediation of water effluents and its integration with an electro-membrane bioreactor
2018
Abstract Photocatalysis and photocatalytic ozonation under visible light have been applied for the purification of a complex aqueous matrix such as the grey water of Masdar City (UAE), by using N-doped brookite-rutile catalysts. Preliminary runs on 4-nitrophenol (4-NP) solutions allowed to test the reaction system in the presence of a model pollutant and to afford the relevant kinetic parameters of the process. Subsequently, the remediation of grey water effluent has been evaluated in terms of the reduction of total organic carbon (TOC) and bacterial counts. The concentration of the most abundant inorganic ionic species in the effluent has been also monitored during reaction. Photocatalytic…
The fouling phenomenon in membrane bioreactors: Assessment of different strategies for energy saving
2013
Abstract Membrane fouling represents one of the major issues for a membrane bioreactor (MBR). Membrane fouling and high aeration requirements (for inducing shear stress to limit fouling) make MBR operation economically demanding due to high energy costs. Although several studies on MBR fouling have been performed, comprehensive knowledge on how to reduce membrane fouling and consequently save energy is still lacking. An integrated mathematical model for MBR is applied to a University of Cape Town membrane bioreactor with the final aim to reduce the energy costs. In particular, the influence of the aeration intensity, the duration of filtration/backwashing cycles, and the number of membrane …
Designing an AnMBR-based WWTP for energy recovery from urban wastewater: The role of primary settling and anaerobic digestion
2015
The main objective of this paper is to assess different treatment schemes for designing a submerged anaerobic membrane bioreactor (AnMBR) based WWTP. The economic impact of including a primary settling (PS) stage and further anaerobic digestion (AD) of the wasted sludge has been evaluated. The following operating scenarios were considered: sulphate-rich and low-sulphate urban wastewater (UWW) treatment at 15 and 30 ºC. To this aim, the optimum combination of design/operating parameters that resulted in minimum total cost (CAPEX plus OPEX) for the different schemes and scenarios was determined. The AnMBR design was based on both simulation and experimental results from an AnMBR plant featuri…
Cost-effectiveness analysis of sewer mining versus centralized wastewater treatment: Case study of the Arga river basin, Spain
2015
ABSTRACT:In the context of the EU Water Framework Directive, a Cost-Effectiveness Analysis (CEA) was performed to compare centralized and decentralized wastewater treatment strategies aimed to improve the ecological status of a Spanish river. The implementation of several hybrid membrane bioreactors within the urban framework for sewer mining (SM) was compared with the more common wastewater treatment plant enlargement option. The assessment ranked 6 alternatives based on 12 potential scenarios, aimed at narrowing the uncertainty of the CEA. The cost analysis illustrated that SM is the most expensive option regarding both investment and operation and maintenance costs. However, the effectiv…
comparing two start-up strategies for MBRs: experimental study and mathematical modelling
2012
Abstract The performance of a membrane bioreactor (MBR), and mechanisms of fouling formation, may differ due to the start-up. Therefore, the start-up can constitute an aspect that critically influences MBR performance during its lifespan. Indeed, the start-up can influence the mechanisms of membrane fouling, which is of paramount importance in an MBR. In order to gain insights on the effects of the start-up, both experimental and mathematical modelling studies were carried out on an MBR pilot plant. The MBR pilot plant constituted of a hollow fibre membrane module, in a submerged configuration, was fed by real wastewater. Two experimental periods were carried out, lasting 65 days each, char…
Variance-based sensitivity analysis for wastewater treatment plant modelling.
2014
Global sensitivity analysis (GSA) is a valuable tool to support the use of mathematical models that characterise technical or natural systems. In the field of wastewater modelling, most of the recent applications of GSA use either regression-based methods, which require close to linear relationships between the model outputs and model factors, or screening methods, which only yield qualitative results. However, due to the characteristics of membrane bioreactors (MBR) (non-linear kinetics, complexity, etc.) there is an interest to adequately quantify the effects of non-linearity and interactions. This can be achieved with variance-based sensitivity analysis methods. In this paper, the Extend…
Uncertainty assessment of a membrane bioreactor model using the GLUE methodology
2010
A mathematical model for the simulation of physical-biological organic removal by means of a membrane bioreactor (MBR) has been previously developed and tested. This paper presents an analysis of the uncertainty of the MBR model. Particularly, the research explores the applicability of the Generalised Likelihood Uncertainty Estimation (GLUE) methodology that is one of the most widely used methods for investigating the uncertainties in the hydrology and that now on is spreading in other research field. For the application of the GLUE methodology, several Monte Carlo simulations have been run varying the all model influential parameters simultaneously. The model was applied to an MBR pilot pl…
Instrumentation, control, and automation for submerged anaerobic membrane bioreactors
2015
A submerged anaerobic membrane bioreactor (AnMBR) demonstration plant with two commercial hollow-fibre ultrafiltration systems (PURON® , Koch Membrane Systems, PUR-PSH31) was designed and operated for urban wastewater treatment. An instrumentation, control, and automation (ICA) system was designed and implemented for proper process performance. Several single-input-single-output (SISO) feedback control loops based on conventional on off and PID algorithms were implemented to control the following operating variables: flow-rates (influent, permeate, sludge recycling and wasting, and recycled biogas through both reactor and membrane tanks), sludge wasting volume, temperature, transmembrane pr…