Search results for " Bone"

showing 10 items of 933 documents

Mandibular connective tissue pedicle flaps in implant dentistry: report of three cases.

2007

Abstract An increase in soft tissues and alveolar bone in the anterior mandibular area between the canines is necessary to achieve a good esthetic result. The present article describes a technique for gaining bone volume and soft tissue to cover bone defects that would otherwise compromise the final result of prosthetic implant restoration in the anterior mandible. Three patients with anterior mandibular atrophy caused by loss of the mandibular incisors are presented. Particulate autologous bone grafting, the raising of a pediculate connective tissue flap to increase soft tissue, and implant placement were carried out simultaneously. After 2 years of follow-up, the implants were in good cli…

AdultMaleAlveolar Bone LossGingivaDentistryConnective tissueMandibleEsthetics DentalTransplantation AutologousSurgical FlapsAtrophyOsseointegrationmedicineHumansDental alveolusOrthodonticsDental ImplantsBone TransplantationImplant dentistrybusiness.industryMandibleSoft tissueAlveolar Ridge AugmentationMiddle Agedmedicine.diseaseIncisormedicine.anatomical_structureConnective TissueFemaleImplantOral SurgeryAtrophybusinessBone volumeFollow-Up StudiesThe Journal of oral implantology
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Treatment of malar and midfacial fractures with osteoconductive forged unsintered hydroxyapatite and poly-L-lactide composite internal fixation devic…

2013

Purpose To evaluate the internal fixation of malar and midfacial fractures, long-term results, and biocompatibility of osteoconductive internal fixation devices composed of a forged composite of unsintered hydroxyapatite and poly-L-lactide (F-u-HA/PLLA). Materials and Methods From January 2006 to June 2010, 29 patients (24 males and 5 females; age 33 ± 15 years) were included in the present prospective study. The fracture type was malar in 24 patients, midfacial in 5, isolated orbital floor blowout in 2, and frontal sinus, cranial base in 2 patients. The fractures were fixed with internal fixation devices; these were plates and screws composed of F-u-HA/PLLA. The 24 patients with malar frac…

AdultMaleBiocompatibilityAdolescentRadiographymedicine.medical_treatmentPolyestersDentistryFractures BoneFracture fixationmedicineInternal fixationHumansProspective StudiesBone growthFrontal sinusZygomabusiness.industryUltrasoundMiddle Agedmedicine.diseaseInternal Fixatorsmedicine.anatomical_structureDurapatiteOtorhinolaryngologyFaceSurgeryFemaleOral SurgeryForeign bodybusinessTomography X-Ray ComputedJournal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
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Herpes Simplex I virus impairs regenerative outcomes of periodontal regenerative therapy in intrabony defects: a pilot study.

2011

Aim To evaluate the impact of herpesvirus type-1 and -2 on the clinical outcomes of periodontal regenerative procedures in isolated deep intrabony pockets, in an experimental population with no detectable periodontal pathogens. Materials and Methods Seventeen periodontal intraosseous defects in 17 moderate-to-advanced periodontitis patients were treated with regenerative therapy and amelogenins. Microbiological evaluation was performed at baseline (after the completion of initial therapy) and at 1 year to exclude the presence of periodontal pathogens. Herpesviruses-1 and -2 DNA were quantified in the pocket tissues associated to the intrabony defect using molecular assays. Clinical attachme…

AdultMaleBone RegenerationCONTROLLED CLINICAL-TRIALHerpesvirus 2 HumanHEALING RESPONSEPopulationAlveolar Bone LossDentistryHerpesvirus 1 HumanACCESS FLAPStatistics NonparametricYoung AdultDental Enamel ProteinsEnamel matrix derivativemedicineAggressive periodontitisHumansPeriodontal PocketGingival RecessionYoung adulteducationBone regenerationGingival recessionGUIDED TISSUE REGENERATIONBONY DEFECTSPeriodontitiseducation.field_of_studybusiness.industryAGGRESSIVE PERIODONTITISMiddle Agedmedicine.diseaseMICROBIOTAHUMAN HERPESVIRUSESPREVALENCEGUIDED TISSUE REGENERATION MINIMALLY INVASIVE SURGICAL TECHNIQUE CONTROLLED CLINICAL-TRIAL AGGRESSIVE PERIODONTITIS HUMAN HERPESVIRUSES HEALING RESPONSE BONY DEFECTS ACCESS FLAP PREVALENCE MICROBIOTAReal-time polymerase chain reactionTreatment OutcomeChronic PeriodontitisDNA ViralGuided Tissue Regeneration PeriodontalPeriodonticsFemaleMINIMALLY INVASIVE SURGICAL TECHNIQUEmedicine.symptombusinessJournal of clinical periodontology
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TNF-α in CRPS and 'normal' trauma--significant differences between tissue and serum.

2011

Posttraumatic TNF-alpha signaling may be one of the factors responsible for pain and hyperalgesia in complex regional pain syndromes (CRPS). In order to further specify the role of TNF-alpha we investigated tissue (skin) and serum concentrations in three different patient groups: patients with osteoarthritis and planned surgery, with acute traumatic upper limb bone fracture waiting for surgery, and with CRPS I. Thirty patients (10 in each group) were recruited. Mean CRPS duration was 36.1 ± 8.1 weeks (range 8- 90 weeks). Skin punch biopsies were taken at the beginning of the surgery in osteoarthritis and fracture patients and from the affected side in CRPS patients. Blood samples were taken…

AdultMaleBone pathologyEnzyme-Linked Immunosorbent AssayPilot ProjectsOsteoarthritisFractures BoneOsteoarthritismedicineHumansAgedSkinAged 80 and overmedicine.diagnostic_testbusiness.industryTumor Necrosis Factor-alphaBone fractureMiddle Agedmedicine.diseaseUp-RegulationAnesthesiology and Pain Medicinemedicine.anatomical_structureComplex regional pain syndromeNeurologyAnesthesiaSkin biopsyHyperalgesiaAcute DiseaseUpper limbWounds and InjuriesTumor necrosis factor alphaFemaleNeurology (clinical)medicine.symptombusinessComplex Regional Pain SyndromesPainReferences
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Influence of bone parameters on peri-implant bone strain distribution in the posterior mandible

2014

Objectives: The success rate of dental implants depends on the type of bone at the implant site. The purpose of the present study was to investigate the effects of the bone parameters at the implant-placement site on peri-implant bone strain distributions. Study Design: The morphologies and bone densities of seventy-five potential implant sites in the posterior man - dible were measured using computed tomography (CT). Based on the CT data, we defined bone parameters (low and high in terms of cancellous-bone density and crestal-cortical bone density, and thin and thick in terms of crestal-cortical bone thickness), and we constructed finite-element models simulating the various bone types. A …

AdultMaleBone thicknessMaterials scienceBone densityDentistryOdontologíaMandiblePeri implant boneHounsfield scalemedicineHumansGeneral Dentistryhealth care economics and organizationsAgedDental ImplantsOrthodonticsPosterior mandiblebusiness.industryResearchMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludBiomechanical Phenomenamedicine.anatomical_structureOtorhinolaryngologyStrain distributionUNESCO::CIENCIAS MÉDICASFemaleSurgeryImplantTomography X-Ray ComputedbusinessImplantologyhuman activitiesCancellous boneMedicina Oral Patología Oral y Cirugia Bucal
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Contrast-enhanced transcranial Doppler ultrasonography in the diagnosis of brain death

2013

The diagnosis of brain death (BD) is based on clinical criteria including deep coma, brain stem areflexia and apnoea. Depending on different local guidelines, confirmatory technical tests are sometimes mandatory.1 Since the 1990s, transcranial Doppler sonography (TCD) has found its place in these circumstances and fulfils most of the criteria of an ‘ideal test’ in confirming BD. To confirm intracranial circulatory arrest (CA) with Doppler sonography, typical flow patterns must be recorded in bilateral intracranial and extracranial brain-supplying arteries.2 A completely absent intracranial flow signal is not a reliable sign to determine CA because this can be due to transmission problems. I…

AdultMaleBrain Deathmedicine.medical_specialtyAdolescentSystoleUltrasonography Doppler TranscranialContrast MediaPhysical examinationYoung AdultEvoked Potentials SomatosensoryIntensive careTemporal bonemedicineHumansChildAgedAged 80 and overBrain deadMicrobubblesmedicine.diagnostic_testbusiness.industryHead injuryUltrasoundElectroencephalographyMiddle Agedmedicine.diseaseTranscranial Doppler ultrasonographyPsychiatry and Mental healthDoppler sonographyCerebrovascular CirculationFemaleSurgeryNeurology (clinical)RadiologybusinessJournal of Neurology, Neurosurgery & Psychiatry
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Outcome of COVID19 in Patients With Osteogenesis Imperfecta: A Retrospective Multicenter Study in Saudi Arabia

2022

BackgroundAlthough genetic diseases are rare, children with such conditions who get infected with COVID-19 tend to have a severe illness requiring hospitalization. Osteogenesis imperfecta (OI) is a rare genetic disorder of collagen resulting in fractures and skeletal deformities. Kyphoscoliosis, restrictive lung disease, and pneumonia worsen the prognosis of patients with OI. The use of bisphosphonate improves bone mineral density (BMD) and reduces fractures in OI. There is no literature describing the impact of COVID-19 in patients with OI.MethodologyA retrospective multi-center study was performed in three hospitals in Jeddah and Riyadh, Saudi Arabia, from March 1st, 2020, until August 31…

AdultMaleCOVID - 19bisphosphonateAdolescentEndocrinology Diabetes and MetabolismSaudi Arabiaosteogenesis imperfectaDiseases of the endocrine glands. Clinical endocrinologyFractures BoneYoung AdultEndocrinologyBone DensityHypothesis and TheoryHumansChildRetrospective StudiesDiphosphonatesSARS-CoV-2COVID-19PrognosisRC648-665HospitalizationfractureoutcomeFemaleFollow-Up StudiesFrontiers in Endocrinology
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[18F]5-fluoro-2-deoxyuridine-PET for imaging of malignant tumors and for measuring tissue proliferation

2003

The nucleoside 5-fluoro-2-deoxyuridine is a pyrimidine analogue accumulating in proliferative cells. We prospectively evaluated biodistribution of the PET tracer [(18)F]5-fluoro-2-deoxyuridine (FdUrd), its value for imaging malignant tumors, and its correlation to both [(18)F]2-fluoro-2-deoxyglucose (FDG)-PET findings and histological proliferation indices. In 11 previously untreated patients (5 lung carcinoma; 3 soft tissue sarcoma; 2 gastrointestinal carcinoma; 1 non-Hodgkin lymphoma [NHL]), mean doses of 290 MBq FdUrd and 390 MBq FDG were administered intravenously on subsequent days. Static PET scans were initiated 50-70 min after administration and the mean standardized uptake values (…

AdultMaleCancer ResearchPathologymedicine.medical_specialtyLung NeoplasmsProliferation indexUrinary BladderKidneyBone and BonesPyrimidine analogueFluorodeoxyglucose F18NeoplasmsmedicineCarcinomaHumansTissue DistributionRadiology Nuclear Medicine and imagingProspective StudiesAgedGastrointestinal NeoplasmsNeoplasm StagingPharmacologymedicine.diagnostic_testbusiness.industryLymphoma Non-HodgkinSoft tissue sarcomaKidney metabolismSarcomaGeneral MedicineMiddle Agedmedicine.diseaseLymphomaKi-67 AntigenLiverOncologyPositron emission tomographyFemaleSarcomaRadiopharmaceuticalsbusinessNuclear medicineCell DivisionTomography Emission-Computed
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Cross-sectional human study of soft tissue chin (STC) thickness in adult patients in relation to sex, facial pattern and skeletal class

2017

Abstract Purpose The aim of this study was to study the relations between the soft tissue chin (STC) and sex, skeletal class, and facial pattern; and to describe the shape and behavior of the STC. Methods 385 non-growing patients were selected, 206 women and 179 men, with a mean age of 28.8 years (SD 4.2). Patients were divided into groups by skeletal class (class I, II or III) and facial pattern (brachyfacial, mesofacial or dolichofacial). STC thicknesses were measured at pogonion (Pg), soft pogonion (Pg′), gnathion (Gn), soft gnathion (Gn′), menton (Me) and soft menton (Me′) in the CBCTs. Results Sexual dimorphism was observed at Pg-Pg′ and Me-Me′. STC thickness was not related to skeleta…

AdultMaleChinMandibular symphysismedicine.medical_treatmentOrthognathic surgeryDentistryFacial BonesYoung Adult03 medical and health sciences0302 clinical medicinemedicineHumans030216 legal & forensic medicineSex Characteristicsbusiness.industryMandibleSoft tissue030206 dentistrySkeletal classChinSexual dimorphismCross-Sectional Studiesmedicine.anatomical_structureOtorhinolaryngologyFaceFemaleSurgeryOral SurgerybusinessSex characteristicsJournal of Cranio-Maxillofacial Surgery
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Analyzing the teeth next to the alveolar cleft: Examination and treatment proposal prior to bone grafting based on three-dimensional versus two-dimen…

2016

Abstract Purpose The objective was to evaluate the diagnostic and prognostic value of three-dimensional (3D) cone beam computed tomography (CBCT) on information about the cleft and alignment of cleft neighboring teeth. Materials and methods Panoramic X-rays, small-volume CBCTs, and study casts of 20 patients with a total of 22 alveolar clefts were analyzed prior to secondary bone grafting. Six maxillofacial surgeons and 6 orthodontists rated the following parameters: visibility of alveolar cleft expansion, position and probability of alignment of cleft neighbored teeth. Two-dimensional (2D) X-rays and casts were rated first; CBCT and casts followed at least 4 weeks later. Radiologic bone he…

AdultMaleCone beam computed tomographyDental radiographyAdolescentmedicine.medical_treatmentTreatment outcomeDentistryBone graftingCohort StudiesYoung Adult03 medical and health sciencesImaging Three-Dimensional0302 clinical medicinePreoperative CareRadiography PanoramicHumansMedicineSurgical preparationBone heightChild030223 otorhinolaryngologyRetrospective StudiesOrthodonticsMaxillofacial surgeonsmedicine.diagnostic_testAlveolar Bone Graftingbusiness.industry030206 dentistryCone-Beam Computed TomographyCleft PalateOtorhinolaryngologyFemaleSurgeryOral SurgeryAlveolar bone graftingbusinessToothJournal of Cranio-Maxillofacial Surgery
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