Search results for " Bone"

showing 10 items of 933 documents

Kinematics of the patellofemoral joint. Investigations on a computer model with reference to patellar fractures.

1990

Patellofemoral kinematics were studied on a computer model. The articulating point of the patella moves from distal to proximal during flexion, until the quadriceps tendon starts to turn around the femur tendo-femoral gliding. The pattern of patellofemoral movement consists of a gliding and rolling component, the latter at its maximum at the beginning of flexion. The pathway of the instant centers of motion moves from dorsal to ventral during flexion. Stress analysis shows that the contact area is at all times the area of maximum bending stress. The distal part of the patella is the part with mechanical stress at all angles of flexion. The conclusions to be drawn for treatment are that frac…

musculoskeletal diseasesmedicine.medical_specialtyKnee Jointmedicine.medical_treatmentMovementKinematicsModels BiologicalFractures BonemedicineInternal fixationHumansOrthopedics and Sports MedicineFemurComputer Simulationbusiness.industryBiomechanicsGeneral MedicineAnatomyPatellamusculoskeletal systemBiomechanical Phenomenamedicine.anatomical_structureOrthopedic surgerySurgeryPatellaQuadriceps tendonContact areabusinessArchives of orthopaedic and trauma surgery
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Long Term Leisure Time Physical Activity Has a Positive Effect on Bone Mass Gain in Girls

2009

The purpose of this 7-year prospective longitudinal study was to examine whether the level and consistency of leisure-time physical activity (LTPA) during adolescence affected the bone mineral content (BMC) and bone mineral density (BMD) attained at early adulthood. The study subjects were 202 Finnish girls who were 10 to 13 years of age at baseline. Bone area (BA), BMC, and BMD of the total body (TB), total femur (TF), and lumbar spine (L2–L4) were assessed by dual-energy X-ray absorptiometry (DXA). Scores of LTPA were obtained by questionnaire. Girls were divided into four groups: consistently low physical activity (GLL), consistently high (GHH), and changed from low to high (GLH) and fro…

musculoskeletal diseasesmedicine.medical_specialtyLongitudinal studyAdolescentEndocrinology Diabetes and MetabolismLeisure timePhysical activityPhysiologyPhysical exerciseMotor ActivityBone and BonesAbsorptiometry PhotonLeisure ActivitiesBone DensitymedicineHumansOrthopedics and Sports MedicineFemurProspective StudiesChildUltrasonographyBone mineralbusiness.industrymusculoskeletal systemCalcaneusPhysical therapyFemaleLumbar spinebusinessBone massJournal of Bone and Mineral Research
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Florid cemento-osseous dysplasia : report of 2 cases

2018

Introduction Florid cemento-osseous dysplasia is a non-neoplastic fibro-osseous lesion which often has an asymptomatic slow growth. Unfortunately, these lesions are usually diagnosed through routine radiographic examination. The aim of this study was to describe the main clinical, radiological and histological characteristics of two case reports diagnosed with florid cemento-osseous dysplasia. Case reports Two cases of florid cemento-osseous dysplasia with different clinical and radiological features were presented. Panoramic radiographs showed multiple radiopacities compatible with fibro-osseous lesions in distinct areas of the maxillary bones. The histological study revealed a sclerotic m…

musculoskeletal diseasesmedicine.medical_specialtyRadiographyCase ReportFibrous tissueMaxillary BonesAsymptomaticLesion03 medical and health sciences0302 clinical medicinestomatognathic systemmedicineOssosDisplàsia fibrosa òssia030223 otorhinolaryngologyGeneral DentistryOral Medicine and PathologyBonesbusiness.industry030206 dentistryFlorid cemento-osseous dysplasiamusculoskeletal systemmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Fibrous dysplasia of bonestomatognathic diseasesEstudi de casosDysplasiaUNESCO::CIENCIAS MÉDICASRadiologyCase studiesmedicine.symptombusinessGigantiform cementoma
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Distal Humerus Fractures

2014

Distal humerus fractures display seldom but severe injuries because of the complex distal humerus anatomy and often comminuted fracture types. They account for approximately 2–3 % of all fractures and for 17–30 % of fractures around the elbow. In younger patients, there is a predominance among males. The mechanism of accident is mostly a high-energy trauma in this population. In contrast, among elderly patients, distal humerus fractures concern mostly women with osteoporotic bone. Fractures are caused by a low-energy trauma such as a fall from standing height onto the outstretched or slightly flexed arm. These fractures are often severely comminuted. Because of the thin soft tissue envelope…

musculoskeletal diseasesmedicine.medical_specialtyeducation.field_of_studybusiness.industryElbowPopulationDistal humerusSoft tissueAnatomymusculoskeletal systemmedicine.diseaseSurgerymedicine.anatomical_structuremedicine.arterymedicineOsteoporotic boneHeterotopic ossificationBrachial arteryeducationbusinessFracture type
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Bestimmung der Knochenqualität vor Wirbelsäuleninstrumentation - Stellenwert verschiedener in vivo-Methoden

2008

OBJECTIVE: The present investigation should elucidate which assessment technique for bone quality is most appropriate to estimate preoperatively fixation strength of instrumental spine fusions. METHODS: VDS-screw fixation strength in 50 human cadaveric vertebral bodies was approximated by means of pullout force assessment. Bone quality was assessed by Dual Energy X-ray Absorptiometry (DEXA), Quantitative Computed Tomography (QCT), MRT and histomorphometry. For each of these techniques, correlation with axial pull out force strength was investigated. RESULTS: Highest correlation was found for cancellous bone density (QCT) (r = 0.72; p < 0.001) and DEXA (r = 0.70; p < 0.001). MRT, cortical bo…

musculoskeletal diseasesmedicine.medical_specialtymedicine.diagnostic_testBone densitybusiness.industrymedicine.medical_treatmentmusculoskeletal systemSurgerymedicine.anatomical_structureSpinal fusionmedicineOrthopedics and Sports MedicineSurgeryCortical boneQuantitative computed tomographyNuclear medicinebusinessCadaveric spasmCancellous boneDual-energy X-ray absorptiometryFixation (histology)Zeitschrift für Orthopädie und ihre Grenzgebiete
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sport nutrition: from Lab to the field held

2018

nutrition bone metabolism markers
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Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03%

2020

Background Exfoliative and erosive cheilitis, may be a source of speech and chewing discomfort, but may also be an aesthetic issue for the patients affected. Such a clinical presentation may implicate a variety of inflammatory conditions, including atopic (eczematous) cheilitis. Topical and systemic agents, e.g. corticosteroids, have been used to treat inflammatory lip conditions. Topical tacrolimus has also been used in some inflammatory lip conditions. Material and Methods We performed a retrospective clinical analysis of atopic cheilitis patients. Results Between 2015 and 2020, we addressed 7 (seven) patients with atopic dermatitis affecting only lips and were diagnosed as atopic-eczemat…

osseodensificationprimary stabilitymedicine.medical_specialtyAdministration TopicalEsthetics DentalTacrolimuslow density boneAtopymedicineHumansGeneral DentistryUNESCO:CIENCIAS MÉDICASRetrospective StudiesrfaOral Medicine and PathologyClinical pathologybusiness.industryResearchAtopic dermatitisTopical tacrolimusmedicine.diseaseDermatologyLipTacrolimusbody regionsstomatognathic diseasesTreatment OutcomeCheilitisOtorhinolaryngologyConcomitantSurgerybusinessImmunosuppressive AgentsMedicina Oral Patología Oral y Cirugia Bucal
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Onset of MRONJ in Breast Cancer Patients after Switching from Low to High Dose of Bone Modifying Agents Due to Bone Metastases Development: A Single …

2022

Background: Medication-Related Osteonecrosis of the Jaw (MRONJ) is an adverse drug reaction mainly associated to bone modifying agents (BMAs). Breast cancer (BC) is the most frequent cancer worldwide. Its therapy can cause cancer treatment-induced bone loss (CTIBL), commonly treated with BMAs. The aims of this retrospective study are: to describe characteristics of BC patients under BMAs for CTIBL; to record any switch to high-dose BMAs; to assess MRONJ onset and to identify any factors associated with it. Patients: Authors included patients referred for MRONJ prevention to the Unit of Oral Medicine (University Hospital of Palermo). Results: Fourteen female BC patients under low-dose BMAs f…

osteonecrosis of the jawbisphosphonatebreast cancerBPosteonecrosis of the jaw; MRONJ; cancer treatment-induced bone loss; CTIBL; breast cancer; osteoporosis; bone metastases; bisphosphonates; BPs; denosumabcancer treatment-induced bone loosteoporosidenosumabPharmacology (medical)MRONJCTIBLbone metastaseOral; Volume 2; Issue 4; Pages: 274-285
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Cell-cycle control in cell-biomaterial interactions

2000

Current biocompatibility testing involves the demonstration of cell proliferation, which is usually interpreted as a sign of positive biocompatibility when the materials sustain cell proliferation. As the field of biomaterials research is rapidly moving toward tissue-engineered devices and hybrid organs, control of cell function has become a main topic. Cell function, which involves specific differentiation pathways, cannot be separated from cell-cycle control. The study of cell-cycle control is an important extension of routine proliferation assays and has extensive roots in developmental and tumor biology. We studied the expression of the tumour suppressor gene p53 and the proliferation-a…

p53BiocompatibilityBiomedical EngineeringFOCAL ADHESION KINASEHUMAN BONEPROTEINBiologyFlow cytometryBiomaterialsFocal adhesionbiomaterials testing methodsmedicineKI-67BREAST-CANCERmedicine.diagnostic_testCell growthINDUCTIONPROLIFERATIONBiomaterialCell cycleCell biologyAPOPTOSISEndothelial stem cellFibronectinDNA-DAMAGEImmunologybiology.proteinendothelial cellcell cycleGROWTH ARRESTJournal of Biomedical Materials Research
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Aetosaur pes from the Upper Triassic of Krasiejów (Poland), with remarks on taxonomy of isolated bones

2021

The incomplete, articulated, right pes of an aetosaur, extracted from the lower bone-bearing horizon of the Krasiejów Late Triassic site, is larger than any other, known from among the Aetosauria. Its individual bones resemble those of at least three genera: Desmatosuchus (astragalus), Typothorax (ungual phalanges), and Stagonolepis (metatarsals). This underscores the highly speculative nature of the taxonomical classification of isolated postcranial bones and makes it impossible to assign the limb to any particular genus. The phalangeal formula is 2-3-4-5-?; for the fifth finger: 2/3/4 is possible. The anatomy of the pes indicates adaptation for digging.

pesAetosauriaStratigraphyEconomic GeologyGeologypostcranial bonesLate TriassicAnnales Societatis Geologorum Poloniae
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