Search results for " Border"
showing 10 items of 142 documents
Granice zewnętrzne Unii Europejskiej a bezpieczeństwo narodowe państw członkowskich w kontekście współczesnego kryzysu migracyjnego
2016
Unia Europejska jest miejscem, w którym swoboda obywateli wyrażona jest poprzez możliwość przemieszania się, podróżowania, pracy,nauki lub życia w wybranym kraju UE. Realizacja tej wolności była wynikiem zniesienia kontroli na granicach wewnętrznych Unii. Jednak dla członka UE ceną tej wolności jest konieczność zapewnienia bezpieczeństwa narodowego, co sprawia, że ochronę granic zewnętrznych postrzega się jako specjalne zadanie. Unia Europejska, za pośrednictwem układu z Schengen, tworzy instytucje w zakresie ochrony granic zewnętrznych, w zakresie zapewnienia bezpieczeństwa narodowego państw członkowskich. Obecny kryzys migracyjny jest weryfikacją skuteczności tych instytucji.
Transnational heritage work and commemorative rituals across the Finnish-Russian border in the old Salla region
2019
Reduced levels of membrane-bound alkaline phosphatase in Vip3Aa-resistant Heliothis virescens
2020
ABSTRACTThe Vip3Aa insecticidal protein fromBacillus thuringiensis(Bt) is produced by specific transgenic corn and cotton varieties for efficient control of target lepidopteran pests. The main threat to this technology is the evolution of resistance in targeted insect pests, thus understanding the mechanistic basis of resistance is crucial to deploy the most appropriate strategies for resistance management. In this work, a laboratory-selected colony ofHeliothis virescens(Vip-Sel) highly resistant to the Vip3Aa protein was used to test whether an alteration of membrane receptors in the insect midgut might explain the resistance phenotype. Binding of125I-labeled Vip3Aa to brush border membran…
Borders on the old maps of Jizera Mountain
2019
Abstract Old maps, mainly from the period between 1890 and 1940, have been collected in the framework of the project “Old Maps of the Jizera Mountains”. These maps provide us with a complex picture, mainly of tourism, in this currently Czech–Polish territory. The territory of the Jizera Mountains was inhabited mainly by a German-speaking population on both sides of the border until 1945. Yet it is interesting to examine how the border between the two states – in those times Czechoslovakia and Germany, now Czechia and Poland – was illustrated on these old maps. This article argues that the border was not perceived as a barrier as such until later on, mainly due to the ethnic change in the bo…
Dual effect of 1-deoxymannojirimycin on the mannose uptake and on the N-glycan processing of the human colon cancer cell line HT-29.
1990
International audience; 1-Deoxymannojirimycin (dMM), a specific alpha-mannosidase I inhibitor, completely blocks the conversion of Man9-8GlcNAc2 into Man7-5-GlcNAc2 in both differentiated and undifferentiated human adenocarcinoma HT-29 cells. Besides this well known effect on N-glycan trimming, we describe here a novel effect of this inhibitor on the D-[2-3H]mannose uptake that is exclusively observed in differentiated intestinal cells, i.e. cells that display a functional apical brush border membrane. This inhibition of D-[2-3H]mannose uptake was shown to be dose-dependent and reversible. Moreover, using microsomal fractions we showed that this effect depends only on the integrity of the b…
Reduced membrane-bound alkaline phosphatase does not affect binding of Vip3Aa in a Heliothis virescens resistant colony
2020
The Vip3Aa insecticidal protein from Bacillus thuringiensis (Bt) is produced by specific transgenic corn and cotton varieties for efficient control of target lepidopteran pests. The main threat to this technology is the evolution of resistance in targeted insect pests and understanding the mechanistic basis of resistance is crucial to deploy the most appropriate strategies for resistance management. In this work, we tested whether alteration of membrane receptors in the insect midgut might explain the >
Exome sequencing in a child with neurodevelopmental disorder and epilepsy: Variant analysis of the AHNAK2 gene
2022
Background The AHNAK2 gene encodes a large nucleoprotein expressed in several tissues, including brain, squamous epithelia, smooth muscle, and neuropil. Its role in calcium signaling has been suggested and to date, clear evidence about its involvement in the pathogenesis of clinical disorders is still lacking. Methods Here, we report a female 24-year-old patient diagnosed with a cardio-facio-cutaneous-like phenotype (CFC-like), characterized by epilepsy, psychomotor development delay, atopic dermatitis, congenital heart disease, hypotonia, and facial dysmorphism, who is compound heterozygote for two missense mutations in the AHNAK2 gene detected by exome sequencing. Results This patient had…
The pronephros of the early ammocoete larva of lampreys (Cyclostomata, Petromyzontes): Fine structure of the renal tubules
1991
The renal tubules of the paired pronephros in early larvae (ammocoetes) of two lamprey species, Lampetra fluviatilis and Petromyzon marinus, were studied by use of light-, scanning- and transmission electron microscopy. They consist of (1) a variable number of pronephric tubules (3 to 6), and (2) an excretory duct. By fine-structural criteria, the renal tubules can be divided into 6 segments. Each pronephric tubule is divided into (1) the nephrostome and (2) the proximal tubule, the excretory duct consisting of (3) a common proximal tubule followed by (4) a short intermediate segment, and then by a pronephric duct composed of (5) a cranial and (6) a caudal section. The epithelium of the nep…
Landscape in transition in the shadow of 2022 Russia’s invasion in Ukraine – notes from Hungary
2022
This research note focuses on two phenomena: the transformations in the landscape in Hungary as an effect of Russia’s invasion in Ukraine and the welcome/help centers that were established to channel mobility and provide a temporary safe space. I suggest that liminality (which serves as a main explanatory category) is characteristic of both. It is stated that in this context that the bodies of refugees are reminders of the existence of the (state) border, which gets reaffirmed by the process of welcoming and hosting and is also reflected in the visual reminders in the landscape. I also divide the management of the refugee crisis into three phases: spontaneous action, institutionalization, a…
Binding analyses of Cry1Ab and Cry1Ac with membrane vesicles from Bacillus thuringiensis-resistant and -susceptible Ostrinia nubilalis.
2004
The binding properties of Bacillus thuringiensis toxins to brush border membrane vesicles of Dipel-resistant and -susceptible Ostrinia nubilalis larvae were compared using ligand-toxin immunoblot analysis, surface plasmon resonance (SPR), and radiolabeled toxin binding assays. In ligand-toxin immunoblot analysis, the number of Cry1Ab or Cry1Ac toxin binding proteins and the relative toxin binding intensity were similar in vesicles from resistant and susceptible larvae. Surface plasmon resonance with immobilized activated Cry1Ab toxin indicated that there were no significant differences in binding with fluid-phase vesicles from resistant and susceptible larvae. Homologous competition assays …