Search results for " CC"
showing 10 items of 188 documents
Hormonal and embryonic regulation of chemokines IL-8, MCP-1 and RANTES in the human endometrium during the window of implantation.
2002
Chemokines are a family of small polypeptides which specialize in the attraction of leukocytes. The presence of specific leukocyte subsets at the implantation site is an important element of the complex, and not completely understood, process of embryonic implantation. This report includes the investigation of the in-vivo immunolocalization and hormonal regulation of interleukin (IL)-8, monocyte chemotactic protein (MCP)-1 and RANTES (regulated upon activation normal T-cell expressed and secreted) in the human endometrium during hormone replacement therapy cycles for oocyte recipients in an IVF programme. In addition, we have analysed the embryonic regulation of these endometrial epithelial…
Elevated serum eotaxin levels in patients with inflammatory bowel disease.
2002
OBJECTIVE: Eotaxin is a recently characterized chemokine with potent and selective chemotactic activity for eosinophils. Previous studies indicating that eosinophils accumulate and become activated in inflammatory bowel disease (IBD) led us to hypothesize that eotaxin is potentially involved in the pathophysiology of IBD and, therefore, that eotaxin would be increased in the serum of patients with IBD. The objective of this study was to test those assumptions. METHODS: We investigated 72 patients with IBD, 35 with ulcerative colitis, and 37 with Crohn’s disease. A total of 27 patients had active and 45 inactive disease; 26 were receiving corticosteroids. Eotaxin serum levels were determined…
En torno al artículo 76.2 del código civil : Comentario a la sap barcelona núm. 21/2020, de 15 de enero
2021
Nullity of marriage due to the spouse´s mistake regarding a significant personal quality of her spouse (art. 73.4º CC) (transvestism). The validation itself requires a conjugal life ininterrupted for a year after the error´s disappearance
Análisis de parámetros biomecánicos durante la recepción en colchonetas y su influencia en los mecanismos de lesión en gimnasia deportiva
2004
Introducción.Entre las acciones técnicas más realizadas en gimnasia deportiva, cabe destacar la recepción sobre la colchoneta, la cual se realiza desde elevadas alturas, generando fuerzas de impacto entre 10 y 18 veces el peso corporal (McNitt-gray. 1993). Pese a la existencia de normas que establecen los criterios a cumplir por una colchoneta, las lesiones durante la recepción tras un salto o salida de un aparato no disminuyen. En este sentido, el Objetivo de esta tesis doctoral fue el de analizar los mecanismos de lesión en gimnasia y su relación con los criterios normativos de las colchonetas. Material y métodos. Los diferentes tipos de estudios planteados fueron: - Estudio de opinión, e…
Evaluación de habilidades cognitivas en la resolución de problemas matemáticos.
2004
En el contexto de la orientación escolar y ante el creciente y significativo porcentaje de alumnos que no superan los objetivos de matemáticas, hemos estudiado, desde el rigor del conocimiento científico y siguiendo el modelo del procesamiento de la información, las variables componenciales que están incidiendo significativamente en el desarrollo de las habilidades cognitivas que intervienen en la resolución de los problemas matemáticos, derivados de los objetivos del primer ciclo de la ESO. Al mismo tiempo, también hemos estudiado la incidencia, en el desarrollo de estas habilidades, de otras variables de tipo personal, experiencial y contextual del alumno. Todo ello, con la finalidad de p…
Histopathology of Skeletal Muscle in a Distal Motor Neuropathy Associated with a Mutant CCT5 Subunit: Clues for Future Developments to Improve Differ…
2023
Genetic chaperonopathies are rare but, because of misdiagnosis, there are probably more cases than those that are recorded in the literature and databases. This occurs because practitioners are generally unaware of the existence and/or the symptoms and signs of chaperonopathies. It is necessary to educate the medical community about these diseases and, with research, to unveil their mechanisms. The structure and functions of various chaperones in vitro have been studied, but information on the impact of mutant chaperones in humans, in vivo, is scarce. Here, we present a succinct review of the most salient abnormalities of skeletal muscle, based on our earlier report of a patient who carried…
Differential diagnosis of cytomegalovirus infection and acute rejection by serum CC-Chemokine measurement after orthotopic liver transplantation
2003
The viral chemokine MCK-2 of murine cytomegalovirus promotes infection as part of a gH/gL/MCK-2 complex.
2013
Human cytomegalovirus (HCMV) forms two gH/gL glycoprotein complexes, gH/gL/gO and gH/gL/pUL(128,130,131A), which determine the tropism, the entry pathways and the mode of spread of the virus. For murine cytomegalovirus (MCMV), which serves as a model for HCMV, a gH/gL/gO complex functionally homologous to the HCMV gH/gL/gO complex has been described. Knock-out of MCMV gO does impair, but not abolish, virus spread indicating that also MCMV might form an alternative gH/gL complex. Here, we show that the MCMV CC chemokine MCK-2 forms a complex with the glycoprotein gH, a complex which is incorporated into the virion. We could additionally show that mutants lacking both, gO and MCK-2 are not ab…
Structure and function of the vacuolar Ccc1/VIT1 family of iron transporters and its regulation in fungi
2020
Iron is an essential micronutrient for most living beings since it participates as a redox active cofactor in many biological processes including cellular respiration, lipid biosynthesis, DNA replication and repair, and ribosome biogenesis and recycling. However, when present in excess, iron can participate in Fenton reactions and generate reactive oxygen species that damage cells at the level of proteins, lipids and nucleic acids. Organisms have developed different molecular strategies to protect themselves against the harmful effects of high concentrations of iron. In the case of fungi and plants, detoxification mainly occurs by importing cytosolic iron into the vacuole through the Ccc1/V…
Ordinamento professionale e mutamento di mansioni nel lavoro pubblico e privato: uno sguardo d'insieme
2021
Il saggio analizza la disciplina del mutamento di mansioni nel lavoro pubblico e privato, con particolare riferimento al rapporto tra lo ius variandi orizzontale e i sistemi di classificazione professionale di fonte contrattual-collettiva. La tesi è che la tecnica del rinvio all’autonomia collettiva, oggi delegata a definire l’area della mobilità orizzontale tanto nel settore pubblico quanto in quello privato, non esclude la sindacabilità delle scelte operate dalle parti sociali, a tutela dei valori costituzionali in cui si invera l’identità professionale del prestatore e contro il rischio di un’eccessiva dilatazione del debito negoziale.