Search results for " CRA"

Buckling and post-buckling analysis of cracked composite plates via a single-domain Ritz approach

2018

Thin and moderately thick composite multi-layered plates are widely employed in many engineering applications, especially in naval and aerospace structures. These structural components can experience in service the presence of cracks, generated for example by corrosion, fatigue or accidental external causes. Cracks can affect the load carrying capability, buckling and post-buckling behaviour of plates; therefore, their effects need to be investigated and taken into account for fail safe or damage tolerant design. Additionally, attention should be devoted to the interaction of cracks with buckling and post-buckling behaviour, as the energy release rate in post-buckling regimes can be adverse…

PLASTICITA CEREBRALE

2007

Management of orphan symptoms: ESMO Clinical Practice Guidelines for diagnosis and treatment†

2020

### Highlights There is no clear definition of orphan symptoms. There is a group of symptoms that are seldom evaluated in most symptom assessment tools which can be considered as orphan symptoms.1 These are generally prevalent symptoms that are unaddressed in clinical practice, yet often not reported by the patients or by healthcare professionals.2 Orphan symptoms may be defined as symptoms not regularly assessed in clinical practice, and consequently little studied and not properly treated. No epidemiological or clinical studies generally exist to gauge the prevalence of the symptoms chosen; nevertheless, these symptoms are distressing for patients and their families. Orphan symptoms remai…

Secondary thyroid carcinoma after treatment for childhood cancer

1998

Background Second malignant neoplasms (SMNs) have become a primary concern in evaluating long-term effects of treatment in pediatric oncology. Thyroid carcinoma has proven to be a common SMN. Methods. In a multicenter study involving 58 hospitals in Germany, Austria and Switzerland, 18 of 239 (7.5%) SMNs documented following first malignant neoplasm (FMN) in childhood were thyroid carcinoma. Results. The age at diagnosis of FMN ranged from 1 to 15 years. Eleven patients were female. Six children had survived Hodgkin disease, seven acute leukemia, two Ewing sarcoma and three various other tumors. Fifteen of the 18 patients had been treated with radiotherapy to the head and neck region. The t…

Pharmacogenomics of Cameroonian traditional herbal medicine for cancer therapy

2011

Abstract Ethnopharmacological relevance A socio-economic burden associated with cancers is reported in Africa. Ethnopharmacological usages such as immune and skin disorders, inflammatory, and others chould be considered when selecting plants used to treat cancer, since these reflect disease states bearing relevance to cancer or a cancer symptoms. Materials and methods Documented compounds of Cameroonian medicinal plants were used as keywords in the National Cancer Institute (NCI) database to establish a library of cytotoxic compounds. Cellular and pharmacogenomic profiling was then performed for the 10 most cytotoxic natural products. By COMPARE and hierarchical cluster analyses, candidate …

Provisional list of succulent species of the Mediterranean Region

1997

Succulent plants are relatively scarce in the Mediterranean Region, and dominant in a few areas. Most species belong to genera of Crassulaceae widespread in the boreal Regions. The main threat for succulents in the area is habitat modification and destruction. Industrial and touristic development, grazing, dams and mining activities are relevant factors of risk, as well as fires and invasive species.

Microstructure-specific carbon isotopic signatures of organic matter from ∼3.5 Ga cherts of the Pilbara Craton support a biologic origin.

2016

21 pages; International audience; The ∼3.5 Ga Dresser Formation from the North Pole Dome of the Pilbara Craton (Western Australia) contains some of the oldest evidence for life on Earth. Here, we present a detailed study of microstructure-specific carbon isotopic composition of organic matter (OM) preserved in Dresser Formation bedded cherts and hydrothermal chert vein using in situ Secondary-Ion Mass Spectrometry (SIMS). The OM in these rocks occurs mainly as clots that, together with minor fine OM layers and laminae, are considered primary textures formed prior to host rock lithification. Other than rare OM-rich stylolites, no evidence was found for later OM migration beyond the micromete…

A kinetic study of the cracking, isomerization, and disproportionation of n-heptane on a chromium-exchanged Y zeolite

1982

The kinetic rate constants for the cracking, isomerization, and disproportionation of n-heptane over a CrHNaY (32% chromium exchanged) zeolite catalyst at 400, 450, and 470 °C have been calculated. The interaction of n-heptane with a model Lewis acid such as BF3 and progress along the reaction coordinate have been studied by means of molecular orbital calculations. From the kinetic results, i.e., activation energies and frequency factors, and the theoretical calculations, it can be concluded that the controlling step in these reactions is not the formation of the carbonium ion, but the subsequent transformation of this carbonium ion. In addition, the theoretical calculations show that the a…

Looking for Feminist Pragmatist Roots of Degrowth Ideas: Jane Addams, Charlotte Perkins Gilman, Caroline Bartlett Crane

2022

The aim of the paper is a search of feminist pragmatist roots of degrowth ideas. The starting point is the question of whether in views of the members of the Progressive Movement the idea of progress has always implied the economic (and industrial) growth. Searching for counter-examples leads me to ideas of ecofeminism and feminist critics of capitalism in the previous turn of the centuries. The ideas of ecofeminism were developed by women associated with the Department of Sociology at the University of Chicago and the social settlement Hull House. They observed a link between the exploitation of subordinate members of a society and the degradation of nature in Western cultural values. The …

The emergence of Vibrio pathogens in Europe : ecology, evolution, and pathogenesis (Paris, 11-12th March 2015)

2015

Global change has caused a worldwide increase in reports of Vibrio-associated diseases with ecosystem-wide impacts on humans and marine animals. In Europe, higher prevalence of human infections followed regional climatic trends with outbreaks occurring during episodes of unusually warm weather. Similar patterns were also observed in Vibrio-associated diseases affecting marine organisms such as fish, bivalves and corals. Basic knowledge is still lacking on the ecology and evolutionary biology of these bacteria as well as on their virulence mechanisms. Current limitations in experimental systems to study infection and the lack of diagnostic tools still prevent a better understanding of Vibrio…