Search results for " Cancer"

How to Report on Distal Resection Margins in Trials on Rectal Cancer Surgery

2018

Inequalities in the participation and outcomes of breast cancer screening programs in Valencia, Spain

2019

Abstract Background Breast cancer remains the most frequent tumour and first cancer related cause of death in the Valencian Community. Despite most of the population being aware of the existence of breast cancer screening programs (BCSP), there are great differences in uptake that are likely attributed to social determinants. The objective of this study, alligning with SDGs 3 and 10, is to assess inequalities in breast cancer screening uptake, diagnosis and treatment delay in the city of Valencia. Methods The population of study included 128 123 women invited to participate in the BCSP in the city of Valencia between 2014 and 2016. Uptake, diagnosis and treatment delay were assessed as outc…

Zonal Segmentation of Prostate T2W-MRI using Atrous Convolutional Neural Network

2019

The number of prostate cancer cases is steadily increasing especially with rising number of ageing population. It is reported that 5-year relative survival rate for man with stage 1 prostate cancer is almost 99% hence, early detection will significantly improve treatment planning and increase survival rate. Magnetic resonance imaging (MRI) technique is a common imaging modality for diagnosis of prostate cancer. MRI provide good visualization of soft tissue and enable better lesion detection and staging of prostate cancer. The main challenge of prostate whole gland segmentation is due to blurry boundary of central gland (CG) and peripheral zone (PZ) which lead to differential diagnosis. Sinc…

Colonoscopy, Tumors, and Inflammatory Bowel Disease - New Diagnostic Methods

2006

Accurate detection of premalignant lesions and early cancers in the colon is essential for curative endoscopic or surgical therapy, since the prognosis for the affected patients is closely related to the size and stage of the neoplastic lesion. Total colonoscopy is the accepted gold standard for screening and surveillance of colorectal cancer. This review summarizes recently published diagnostic developments and key findings in the areas of colonoscopy, colonic tumors, and inflammatory bowel diseases. Relevant findings have been reported for chromo-endoscopy in the diagnosis of colitis-associated neoplasia, as well as flat and depressed adenomas. Real-time Doppler capabilities have now been…

Endoscopic Management for Patients with Serrated Polyposis Syndrome is Feasible and Effective:

2014

Background and Study Aims: Serrated polyposis syndrome is a rare condition in which multiple serrated lesions develop all over the colon, which is thought to be associated with an increased risk for the development of cancer. The aim of this study was to investigate the feasibility of endoscopic treatment and standardised surveillance in patients with this increasingly recognised syndrome. Methods: From September 2010 to November 2013, consecutive patients were included in a prospective study. All patients underwent chromoendoscopy at first presentation and during surveillance. Follow-up examinations were carried out at 3 month intervals until complete clearance was achieved. Afterwards, pa…

Colorectal Polyps

2008

Publisher Summary Colorectal cancer (CRC) remains the second leading cause of cancer death for both women and men with more than 130,000 newly diagnosed cases and 50,000 deaths each year in the United States alone. Most colon cancers develop from nonmalignant colonic adenomas or polyps over a comparatively long time period ranging between 24 and 60 months. Reflecting this adenomatous pathogenesis of most colorectal cancers, polyp screening with subsequent polypectomy is used to constitute an effective approach for decreasing the incidence of this malignant tumor. Thus, colorectal screening for polyps may be considered one of the most promising preventive measures in medicine. Most available…

EP1299 Laparoscopic – laterally extended pelvic resection

2019

Introduction/Background Lateral isolated gynecological cancer infiltrating the pelvic side wall (PSW) has been considered as a not operable surgery with poor oncological outcome. The development of the laterally extended endopelvic resection (LEER) and surgical progress for disease overcoming the endopelvic fascia infiltrating muscles and nerves, have achieved the possibility to treat those patients with a curative intent. We describe for the first time the feasibility of laparoscopic laterally extended pelvic resection (L-LEPR), with complete removal of disease. Methodology LEPR was defined as an en bloc lateral resection of a pelvic tumor involving sidewall muscle, and/or bone, and/or maj…

Endometrial cancer: Robotic versus Laparoscopic treatment. Preliminary report

2015

Laparoscopic approach is today the standard treatment for benign and malignant gynecological pathologies. To traditional laparoscopic surgery in the last 10 years we can add the possibility to use a robotic platform. The adoption of this system allows undoubted advantages as the three-dimensional vision, the absence of the physiological tremor with enhanced ergonomics and possibility of using articulable tools. In this study we analyzed the results of 18 patients with endometrial cancer (Stage I) treated with robotic approach. The results were compared with a selected sample of 26 patients, with the same characteristics, treated with traditional laparoscopic approach in the same period by t…

Laparoscopic sentinel lymph node mapping and excision of the rectum using a radioactive tracer — a prospective experimental study

2009

Introduction: Patients with a low risk T1 rectal carcinoma can undergo the therapy of a local excision. In these patients the lymph node status remains unknown. There is a potential risk of up to 7% for nodal metastasis, in high risk cases it can rise up to 35%. To investigate the possibility of using the Sentinel lymph node (SLN) concept, which is anchored in the therapy of malignant melanoma and breast cancer, an experimental study on pigs was undertaken. The objective of the study was to laparoscopically identify and extract SLN’s from the rectum using a radioactive tracer (RT). Material und Methods: The experiment was conducted upon 30 pigs, because sample size calculation indicated tha…

Peut-on proposer un prélèvement du ganglion sentinelle en cas de chimiothérapie néoadjuvante dans les cancers du sein et à quel moment ?

2016

The main goal of preoperative chemotherapy is to reduce the size of the tumor and allow conservative treatment. Neoadjuvant treatment can affect axillary status with a downstaging in one third of the cases. For these patients, the benefit of axillary node dissection is questioned and the sentinel node biopsy (SLNB) seems to be a relevant option. However, the timing of performing SLNB is still debated especially for clinical negative patients with negative axillary ultrasound before preoperative chemotherapy. For axillary positive nodes proved by biopsy/cytology before preoperative chemotherapy, SLNB can be an option if there is a good clinical and radiological response.