Search results for " Cardiovascular risk"

showing 10 items of 115 documents

Coffee components and cardiovascular risk: beneficial and detrimental effects

2014

Coffee consists of several biological active compounds, such as caffeine, diterpenes, chlorogenic acids, and melanoidins, which may affect human health. The intake of each compound depends on the variety of coffee species, roasting degree, type of brewing method and serving size. The bioavailability and the distribution of each compound and its metabolites also contribute to coffee mechanisms of action. The health benefits of coffee consumption regarding cardiovascular system and metabolism mostly depend on its antioxidant compounds. In contrast, diterpenes and caffeine may produce harmful effects by raising lipid fraction and affecting endothelial function, respectively. Studying the mecha…

AntioxidantSettore MED/09 - Medicina InternaPolymersmedicine.medical_treatmentLipid fractionCoffee consumptionBiologyHealth benefitsCardiovascular SystemCoffeeHuman healthchemistry.chemical_compoundAlkaloidsCaffeinemedicineHumansFood scienceSettore MED/49 - Scienze Tecniche Dietetiche ApplicatePlant ExtractsPolyphenolscoffee cardiovascular riskDiabetes Mellitus Type 2chemistryCardiovascular DiseasesChlorogenic AcidDiterpenesCaffeineFood Science
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Filling the gap between Guidelines and Real World in the cardiovascular approach to the diabetic patients: the need for a call to action

2020

Blood GlucoseAmerican diabetes associationmedicine.medical_specialtybusiness.industryLow density lipoprotein cholesterolCardiovascular outcome trials Cardiovascular prevention Cardiovascular risk Diabetes mellitus type 2 Glucose-lowering drugs Therapeutical targets Blood Glucose Humans Hypoglycemic Agents Cardiovascular Diseases Diabetes Mellitus Type 2 Sodium-Glucose Transporter 2 InhibitorsCall to actionProprotein Convertase Subtilisin/Kexin 9Diabetes Mellitus Type 2Cardiovascular preventionCardiovascular DiseasesHumansHypoglycemic AgentsMedicineCardiology and Cardiovascular MedicinebusinessIntensive care medicineSodium-Glucose Transporter 2 InhibitorsGlycated haemoglobin
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Levothyroxine and insulin requirement in autoimmune polyglandular type 3 syndrome: a real-life study

2020

Abstract Purpose To evaluate factors influencing the insulin and levothyroxine requirement in patients with autoimmune polyglandular syndrome type 3 (APS-3) vs. patients with type 1 diabetes mellitus (T1DM) and autoimmune hypothyroidism (AH) alone, respectively. Methods Fifty patients with APS-3, 60 patients with T1DM and 40 patients with AH were included. Anthropometric, clinical and biochemical parameters were evaluated in all patients. Insulin requirement was calculated in patients with APS-3 and T1DM, while levothyroxine requirement was calculated in APS-3 and AH. Results Patients with APS-3 showed higher age (p = 0.001), age of onset of diabetes (p = 0.006) and TSH (p = 0.004) and lowe…

Blood GlucoseMale0301 basic medicineendocrine system diseasesEndocrinology Diabetes and Metabolismmedicine.medical_treatmentAdipose tissueGastroenterologySettore MED/13 - Endocrinologia0302 clinical medicineEndocrinologyAutoimmune hypothyroidism Cardiovascular risk Irisin Type 1 diabetes mellitus Visceral adiposity indexInsulinPolyendocrinopathies AutoimmuneThyroid diseaseMiddle AgedPrognosisFemaleOriginal Articlemedicine.drugAdultIrisinmedicine.medical_specialtyWaistAdolescentLevothyroxineType 1 diabetes mellitus030209 endocrinology & metabolismHashimoto DiseaseYoung Adult03 medical and health sciencesInternal medicineDiabetes mellitusmedicineHumansHypoglycemic AgentsAgedType 1 diabetesAutoimmune hypothyroidismbusiness.industryInsulinThyroiditis AutoimmuneCardiovascular riskmedicine.diseaseVisceral adiposity indexThyroxineDiabetes Mellitus Type 1030104 developmental biologyAge of onsetbusinessBiomarkersFollow-Up StudiesJournal of Endocrinological Investigation
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Impact of a Mediterranean Dietary Pattern and Its Components on Cardiovascular Risk Factors, Glucose Control, and Body Weight in People with Type 2 D…

2018

This study evaluates the relation of a Mediterranean dietary pattern and its individual components with the cardiovascular risk factors profile, plasma glucose and body mass index (BMI) in people with type 2 diabetes. We studied 2568 participants at 57 diabetes clinics. Diet was assessed with the EPIC (European Prospective Investigation into Cancer and Nutrition) questionnaire, adherence to the Mediterranean diet was evaluated with the relative Mediterranean diet score (rMED). A high compared to a low score was associated with a better quality of diet and a greater adherence to the nutritional recommendations for diabetes. However, even in the group achieving a high score, only a small prop…

Blood GlucoseMaleMediterranean diet; cardiovascular risk; diabetes; glucose control; plasma lipids; relative Mediterranean diet score; Aged; Biomarkers; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mellitus Type 2; Female; Glycated Hemoglobin A; Humans; Lipids; Male; Middle Aged; Nutritive Value; Patient Compliance; Protective Factors; Recommended Dietary Allowances; Risk Factors; Body Mass Index; Diet Healthy; Diet Mediterranean; Feeding BehaviorGlycated Hemoglobin AMediterranean dietRecommended Dietary AllowanceCross-sectional studyHealthy DietSaturated fatBlood PressureType 2 diabetes030204 cardiovascular system & hematologyMediterraneanDiet MediterraneanDiabeteRecommended Dietary AllowancesSettore MED/13 - EndocrinologiaBody Mass Indexchemistry.chemical_compound0302 clinical medicineRisk FactorsCardiovascular Disease030212 general & internal medicineNutrition and DieteticsdiabetesLipidMiddle AgedLipidsEuropean Prospective Investigation into Cancer and NutritionCardiovascular DiseasesFemaleDiet Healthylcsh:Nutrition. Foods and food supplyNutritive ValueType 2Humancardiovascular riskCardiovascular risk; Diabetes; Glucose control; Mediterranean diet; Plasma lipids; Relative mediterranean diet score; Aged; Biomarkers; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mellitus Type 2; Female; Glycated Hemoglobin A; Humans; Lipids; Male; Middle Aged; Nutritive Value; Patient Compliance; Protective Factors; Recommended Dietary Allowances; Risk Factors; Body Mass Index; Diet Mediterranean; Feeding Behavior; Healthy Diet; Food Science; Nutrition and DieteticsPlasma lipidlcsh:TX341-641Article03 medical and health sciencesEnvironmental healthDiabetes mellitusMediterranean dietplasma lipidsmedicineDiabetes MellitusHumansProtective FactorAgedCross-Sectional StudieGlycated Hemoglobinglucose controlHealthybusiness.industryRisk FactorBiomarkerFeeding Behaviorrelative Mediterranean diet scoreProtective Factorsmedicine.diseaseDietCross-Sectional StudieschemistryDiabetes Mellitus Type 2Patient ComplianceGlycated hemoglobinbusinessBody mass indexBiomarkersFood Science
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Prevalence of 'borderline' values of cardiovascular risk factors in the clinical practice of general medicine in Italy: results of the BORDERLINE stu…

2011

Introduction: The prevalence of patients with 'borderline' levels of cardiovascular risk factors has been rarely investigated, being often reported in studies evaluating abnormal values of these parameters. The BORDERLINE study represents a pilot experience to primarily identify the prevalence of 'high-normal' conditions, such as pre-hypertension, lipid and glucose levels in the upper range of normality in the setting of general practice in Italy. Aim: The aim of this study was to evaluate the prevalence of patients with 'borderline' values of cardiovascular risk factors in Italy. Methods: Involved physicians were asked to evaluate the first 20 outpatients, consecutively seen in June 2009. …

Blood GlucoseMaleSettore MED/09 - Medicina InternaGeneral PracticeBlood PressurePilot ProjectsDiseasechemistry.chemical_compoundPrehypertensionRisk FactorsPrevalenceMedicineglucoseeducation.field_of_studycardiovascular risk factors general medicine borderline studiescardiovascular preventionMiddle AgedLipidsItalyCardiovascular Diseaseshigh-normal riskborderline risk high-normal risk cardiovascular prevention global cardiovascular risk blood pressure cholesterol glucoseFemaleCardiology and Cardiovascular Medicinemedicine.medical_specialtyCardiovascular risk factorsPopulationDiastoleRisk AssessmentPharmacotherapyInternal medicineInternal MedicineHumansborderline riskglobal cardiovascular riskeducationPsychiatryAgedDyslipidemiasGlucose Metabolism DisordersChi-Square Distributionbusiness.industryCholesterolcholesterolMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREborderline risk; high-normal risk; blood pressure; global cardiovascular risk; glucose; cardiovascular prevention; cholesterolHealth SurveysBlood pressurechemistryArterial Hypertension Epidemiology Cardiovascular RiskbusinessBody mass indexBiomarkers
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Subclinical atherosclerosis and history of cardiovascular events in Italian patients with rheumatoid arthritis: Results from a cross-sectional, multi…

2017

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Blood GlucoseMalerheumatoid arthritisCross-sectional studyType 2 diabetesTriglycerideArthritis Rheumatoid0302 clinical medicineRisk FactorsCardiovascular DiseasePrevalence030212 general & internal medicineMyocardial infarctionStrokeSubclinical infectionAged 80 and overMetabolic SyndromeMetabolic Syndrome XGeneral MedicineMiddle Agedinflammatory processCholesterolItalyCardiovascular DiseasesRheumatoid arthritisAtherosclerosiHypertensionComputingMethodologies_DOCUMENTANDTEXTPROCESSINGFemaleHumanResearch ArticleAdultmedicine.medical_specialtyAdolescentsubclinical atherosclerosisObservational Study03 medical and health sciencesYoung Adultcardiovascular eventsInternal medicinemedicineHumansTriglyceridesAged030203 arthritis & rheumatologyCross-Sectional Studiebusiness.industryRisk Factor6900medicine.diseaseAtherosclerosisCross-Sectional StudiesDiabetes Mellitus Type 2Physical therapyMetabolic syndromebusinessRheumatismtraditional cardiovascular risk factorMedicine
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Prognostic Value of Ambulatory Blood Pressure Monitoring in Refractory Hypertension : A Prospective Study

1998

The objective of this study was to establish whether ambulatory blood pressure offers a better estimate of cardiovascular risk than does its clinical blood pressure counterpart in refractory hypertension. This prospective study assessed the incidence of cardiovascular events over time during an average follow-up of 49 months (range, 6 to 96). Patients were referred to specialized hypertension clinics (86 essential hypertension patients who had diastolic blood pressure >100 mm Hg during antihypertensive treatment that included three or more antihypertensive drugs, one being a diuretic). Twenty-four-hour ambulatory blood pressure monitoring (ABPM) was performed at the time of entrance. End-or…

Blood pressure monitoring ambulatory ; Hypertension refractory ; Cardiovascular risk ; Prognosis:CIENCIAS MÉDICAS ::Medicina interna [UNESCO]UNESCO::CIENCIAS MÉDICASHypertension refractoryCardiovascular riskPrognosis:CIENCIAS MÉDICAS [UNESCO]Blood pressure monitoring ambulatoryUNESCO::CIENCIAS MÉDICAS ::Medicina interna
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Polyvascular subclinical atherosclerosis in familial hypercholesterolemia: The role of cholesterol burden and gender

2019

International audience; BACKGROUND AND AIM:Heterozygous familial hypercholesterolemia (HeFH) is a genetic disease characterized by a heterogeneous phenotype. The assessment of cardiovascular (CV) risk is challenging for HeFH. Cholesterol burden (CB) allows to estimate the lifelong exposure to high levels of cholesterol. The aim of this study was to analyze the distribution of subclinical atherosclerosis and the relationship between atherosclerosis and the CB in a sample of HeFH patients, focusing on sex-related differences.METHODS AND RESULTS:154 asymptomatic HeFH subjects underwent coronary-artery-calcium score (CACs) and Doppler ultrasound of carotid and femoral arteries. Yearly lipid pro…

Carotid Artery DiseasesMaleCarotid atherosclerosisPeripheral arterial atherosclerosisTime Factors[SDV]Life Sciences [q-bio]Endocrinology Diabetes and MetabolismMedicine (miscellaneous)Coronary Artery DiseaseDiseaseFamilial hypercholesterolemia030204 cardiovascular system & hematologySeverity of Illness Indexchemistry.chemical_compound0302 clinical medicineRisk FactorsAtherosclerosis; Calcium score; Cardiovascular disease; Cardiovascular risk; Cholesterol burden; Coronary artery calcium; Familial hypercholesterolemia; Peripheral arterial atherosclerosis; Adult; Aged; Asymptomatic Diseases; Biomarkers; Carotid Artery Diseases; Cholesterol; Coronary Artery Disease; Cross-Sectional Studies; Female; Femoral Artery; Genetic Predisposition to Disease; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Paris; Peripheral Arterial Disease; Phenotype; Prevalence; Prognosis; Risk Assessment; Risk Factors; Severity of Illness Index; Sex Factors; Time Factors; Young AdultPrevalenceMedicineNutrition and Dietetics[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolismMiddle AgedPrognosisCardiovascular diseaseCalcium score3. Good healthFemoral ArteryCholesterol burdenCholesterolPhenotypeAtherosclerosiCardiologyPopulation studyFemalemedicine.symptomCardiology and Cardiovascular MedicineAdultParismedicine.medical_specialtyFamilial hypercholesterolemia030209 endocrinology & metabolismRisk AssessmentAsymptomaticCoronary artery calciumHigh cholesterolHyperlipoproteinemia Type IIPeripheral Arterial DiseaseYoung Adult03 medical and health sciencesSex Factors[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemInternal medicineHumansGenetic Predisposition to DiseaseAgedbusiness.industryCholesterolAtherosclerosismedicine.diseaseCardiovascular riskCross-Sectional StudieschemistrySubclinical atherosclerosisAsymptomatic DiseasesbusinessBiomarkers
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Impact of preclinical carotid atherosclerosis on global cardiovascular risk stratification and events in a 10-year follow-up: comparison between the …

2019

Background The aim of the study was to compare three widely used algorithms for stratification of the global cardiovascular risk (GCVR): the Framingham Heart Study (FHS) score, the European systemic coronary risk estimation (SCORE) and the Italian 'Progetto Cuore' (heart project) score. It was also investigated how preclinical carotid atherosclerosis (pre-ATS) might influence the incidence and improve the risk prediction of cerebrovascular and cardiovascular events. Methods Subjects (n = 358) without previous history of cardiovascular disease (CVD) were recruited and the GCVR was calculated for each patient. An ultrasound evaluation of the carotid arteries was also performed. Results Accord…

Carotid Artery DiseasesMaleTime Factorsintima-media thickening (IMT)Predictive Value of TestDisease030204 cardiovascular system & hematologyCarotid Intima-Media ThicknessDecision Support Technique0302 clinical medicineFramingham Heart StudyRisk FactorsProspective Studies030212 general & internal medicineProspective cohort studyasymptomatic carotid plaque (ACP)education.field_of_studyIncidence (epidemiology)IncidenceGeneral MedicineMiddle AgedPrognosisPlaque AtheroscleroticAlgorithmItalypreclinical carotid atherosclerosis (pre-ATS)Predictive value of testsCerebrovascular DisorderDisease ProgressionFemalemedicine.symptomRisk assessmentCardiology and Cardiovascular MedicineAlgorithmAlgorithmsHumanAdultTime FactorPrognosiPopulationglobal cardiovascular risk (GCVR)AsymptomaticRisk AssessmentDecision Support TechniquesFollow-Up Studie03 medical and health sciencesPredictive Value of TestsCarotid Intima-Media ThicknemedicineHumanseducationAgedAsymptomatic DiseaseCarotid Artery Diseasebusiness.industryRisk Factoralgorithms of cardiovascular riskCerebrovascular DisordersProspective StudieAsymptomatic DiseasesbusinessFollow-Up Studies
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An assessment of the hemorheological profile in patients with subclinical carotid atherosclerosis divided in relation to the number of cardiovascular…

2021

We present a cohort of 100 subjects [43 men and 57 women; median age 66.00(25)] who were tested using carotid ultrasound to identify subclinical carotid atherosclerosis (SCA). We have evaluated the behaviour of whole blood viscosity (WBV) at high (450 s–1) and low (0.51 s–1) shear rates, plasma viscosity (450–1), hematocrit and mean erythrocyte aggregation. When compared to normal control subjects, using the Mann-Whitney test, we observed in SCA patients a significant increase in WBV only. The results were substantial after having divided the SCA subjects according to the cardiovascular risk factors (CRFs) and the degree of insulin resistance; the research was performed using two surrogate …

Carotid Artery DiseasesMalemedicine.medical_specialtyPhysiologyCardiovascular risk factors030204 cardiovascular system & hematologyHematocritFibrinogenErythrocyte aggregation030218 nuclear medicine & medical imaging03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInsulin resistanceuric acidRisk FactorsPhysiology (medical)Internal medicinemedicineHumanstraditional cardiovascular risk factorsSubclinical infectionAgedSubclinical carotid atherosclerosismedicine.diagnostic_testbusiness.industryhemorheological determinantsHematologymedicine.diseaseBlood ViscositychemistryCardiovascular DiseasesHeart Disease Risk FactorsCohortCardiologyUric acidFemaleInsulin Resistanceinsuline-resistenceCardiology and Cardiovascular Medicinebusinessmedicine.drugClinical hemorheology and microcirculation
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