Search results for " Cell"

Effects of ectopic expression of NGAL on doxorubicin sensitivity.

2012

Neutrophil gelatinase-associated lipocalin (NGAL, a.k.a Lnc2) is a member of the lipocalin family which has diverse roles including stabilizing matrix metalloproteinase-9 from auto-degradation and as siderocalins which are important in the transport of iron. NGAL also has important biological functions involved in immunity and inflammation as well as responses to kidney damage. NGAL expression has also been associated with certain neoplasia and is important in the metastasis of breast cancer. Many advanced cancer patients have elevated levels of NGAL in their urine and it has been proposed that NGAL may be a prognostic indicator for certain cancers (e.g. breast, brain, and others). NGAL exp…

UPTAKE OF SILICA COVERED QUANTUM DOTS ON LIVING CELLS: LONG TERM VITALITY AND MORPHOLOGY STUDY ON HYALURONIC ACID BIOMATERIALS

2015

In this work we prepared colloidal CdSe-CdS core-shell nanocrystal emitting @625 nm and, by a micro-emulsion procedure of water in oil inverse micelle, we encapsulated a single dot inside each silica sphere. In this way the nanoparticles became biocompatible, are simply to prepare and could be used also in a water based environment. Moreover, the silica shield is transparent to the wavelengths of interest.

Skin Immunomodulation during Regeneration: Emerging New Targets

2021

Adipose-Derived Stem Cells (ADSC) are present within the hypodermis and are also expected to play a pivotal role in wound healing, immunomodulation, and rejuvenation activities. They orchestrate, through their exosome, the mechanisms associated to cell differentiation, proliferation, and cell migration by upregulating genes implicated in different functions including skin barrier, immunomodulation, cell proliferation, and epidermal regeneration. ADSCs directly interact with their microenvironment and specifically the immune cells, including macrophages and T and B cells, resulting in differential inflammatory and anti-inflammatory mechanisms impacting, in return, ADSCs microenvironment and …

Hopes and Limits of Adipose-Derived Stem Cells (ADSCs) and Mesenchymal Stem Cells (MSCs) in Wound Healing

2020

Adipose tissue derived stem cells (ADSCs) are mesenchymal stem cells identified within subcutaneous tissue at the base of the hair follicle (dermal papilla cells), in the dermal sheets (dermal sheet cells), in interfollicular dermis, and in the hypodermis tissue. These cells are expected to play a major role in regulating skin regeneration and aging-associated morphologic disgraces and structural deficits. ADSCs are known to proliferate and differentiate into skin cells to repair damaged or dead cells, but also act by an autocrine and paracrine pathway to activate cell regeneration and the healing process. During wound healing, ADSCs have a great ability in migration to be recruited rapidly…

Maturation of Epidermal Langerhans Cells In Vitro Is Accompanied by Downregulation of 4F2 (CD98) as Determined by Differential Display

1998

Following short-term culture, Langerhans cells mature morphologically and functionally into potent immunostimulatory cells. As regulation of gene expression accompanies this maturation process, it is likely that differentially expressed genes are involved in the maturation events. Using the recently described method of differential display, we generated cDNA expression patterns starting with mRNA of murine epidermal Langerhans cells isolated either directly (fLC) or following 3 d cultivation (cLC). Five hundred putative differentially expressed cDNA fragments were recovered from the gel. For a part of the fragments differential expression was confirmed by dot blot and Southern hybridization…

Advanced performance monitoring for self-healing cellular mobile networks

2015

This dissertation is devoted to development and validation of advanced per- formance monitoring system for existing and future cellular mobile networks. Knowledge mining techniques are employed for analysis of user specific logs, collected with Minimization of Drive Tests (MDT) functionality. Ever increas- ing quality requirements, expansion of the mobile networks and their extend- ing heterogeneity, call for effective automatic means of performance monitoring. Nowadays, network operation is mostly controlled manually through aggregated key performance indicators and statistical profiles. These methods are are not able to fully address the dynamism and complexity of modern mobile networks. Se…

Fabrication and Characterization of Dye-Sensitized Solar Cells

2014

Among the next-generation solar cells, a predominant role is played by Dye sensitized solar cells (DSSC) based on ruthenium complexes as sensitizers. They take advantage of a photoelectrochemical system to transform solar radiation into electric energy. In fact, DSSCs represent a cost-effective alternative to traditional silicon-based photovoltaic devices and they do not require expensive and sophisticated apparatus for their fabrication. In this work, we have produced and tested ruthenium DSSCs. In particular, we have measured the main parameters of these cells, such as the electrical and power performances and the efficiency levels, at different irradiance levels and at different incident…

Interfacial Engineering in Vacuum-Deposited Perovskite Solar Cells for Improved Performance and Space Stability

2021

Perovskite solar cells are an emerging technology that is evolving rapidly, with power conversion efficiency values that compete with traditional materials such as silicon. In this type of solar cells the photons are absorbed in the perovskite and the charges are extracted using transport materials. By sandwiching the perovskite between a material with and excess of negative (N) or positive (P) charge, one can fabricate a P-i-N or N-i-P structure depending on the deposition order of the materials. Perovskite solar cells have several advantages, mainly the possibility of being very thin thanks to the high absorption coefficient of the perovskite and the wide range of deposition techniques, c…

NANOWIRES AND THIN FILMS OF CIS/CIGS OBTAINED BY ELECTRODEPOSITION AS ABSORBER FOR SOLAR CELLS

2011

CuInSe2/Zn(S,O,OH) junction by electrochemical and chemical route for photovoltaic applications (GE 2014)

2014

Electrodeposition is a convenient technique for the development of low cost materials for photovoltaic (PV) device processing. Using a single step electrodeposition route, several groups have fabricated CIS (CuInSe) and CIGS (CuInGaSe) films. One of the most important requirements for successful application of one-step electrodeposition film formation is the ability to control composition of the deposited films and to develop polycrystalline microstructures with a low surface roughness and high sintered density.