Search results for " Central"

showing 10 items of 560 documents

Clinical evaluation of neodymium-iron-boron (Ne2Fe14B) rare earth magnets in the treatment of mid line diastemas

2015

Background: To evaluate the closure of midline diastema using the Neodymium-Iron-Boron magnets and to compare the treatment duration of midline diastemas with the use of magnets compared to regular orthodontic treatment. Materials and Methods: Thirty patients with age group 12 to 30 years with the midline diastema ranging from 0.5 to 3mm were selected. These patients were divided into two groups. Diastema closure in one group was accomplished by conventional method, in other group was done with Ne 2 Fe 14 B magnets. These magnets were fitted to the labial surfaces of the maxillary central incisors such a way that the opposite poles of the magnets face each other. At each appointment, study …

Neodymium iron boronRare earthDentistryOrthodonticsOdontología02 engineering and technology03 medical and health sciences0302 clinical medicineMedicineMaxillary central incisorGeneral Dentistrybusiness.industryResearchSignificant difference030206 dentistry021001 nanoscience & nanotechnologyequipment and supplies:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludMagnetDiastemaUNESCO::CIENCIAS MÉDICASCalipers0210 nano-technologybusinessClinical evaluationhuman activities
researchProduct

Thyroid hormones and the central nervous system of mammals (Review)

2008

Abstract. The thyroid hormones (THs) L-thyroxine (T4) and L-triiodothyronine (T3) have a profound influence on the development and maturation of the mammalian brain, both before and after birth. Any impairment in the supply of THs to the developing nervous system leads to severe and irreversible changes in both the overall architecture and functions of the brain and causes, in humans, neurological and motor deficits known as cretinism. Pronounced neurological symptoms are also commonly observed in adult patients suffering from both hyperthyroidism and hypothyroidism, and it has recently emerged that certain symptoms might result from the reduced brain uptake, rather than the insufficient pr…

Nervous systemGene isoformeffetti non-genomiciCancer Researchmedicine.medical_specialtyCentral nervous systemBiologyormoni tiroidei; sviluppo del cervello; sistema nervoso centrale (CNS); recettori nucleari; effetti non-genomiciBiochemistryormoni tiroideiInternal medicineSettore BIO/10 - BiochimicaGeneticsmedicineTranscriptional regulationsistema nervoso centrale (CNS)ReceptorMolecular Biologymedicine.diseaseEndocrinologymedicine.anatomical_structureOncologyNuclear receptorsviluppo del cervelloMolecular MedicineCretinismrecettori nucleariHormone
researchProduct

Viaggi nell’immaginario: il turismo virtuale nel sito UNESCO di Tarragona

2023

Le nuove tecnologie hanno trasformato in modo radicale non solo la geografia come disciplina, ma anche le geografie del mondo. Il digitale ha assunto, infatti, un ruolo di mediazione sempre più pervasivo nella produzione dello spazio, come delle conoscenze e degli immaginari geografici. Le possibilità offerte dal virtuale, in particolare, offrono oggi un contributo decisivo nella comunicazione dei significati attribuiti ai luoghi e rispondono in modo sempre più efficace ai bisogni emergenti del settore turistico. Le esperienze di visita mediate dal digitale mirano a coinvolgere i sensi e risultano efficaci quando promuovono immersioni rigorosamente realistiche. Nel quadro di queste riflessi…

New technologies have radically transformed not only geography as a discipline but also the geographies of the world. Indeed the digital has assumed an increasingly pervasive mediating role in the production of space as of geographic knowledge and imaginaries. The possibilities offered by the virtual in particular now offer a decisive contribution in communicating the meanings attributed to places and respond increasingly effectively to the emerging needs of the tourism sector. Digitally mediated visitor experiences aim to engage the senses and are effective when they promote rigorously realistic immersions. Within the framework of these reflections the paper highlights the renewed relevance of authenticity both of the tourism experience and of cultural heritage in relation to its potential for attraction and proposes a contextualization of the theme in light of the unprecedented opportunities granted by technologies for the creation of virtual and augmented spaces. The proposed discussion is therefore also a journey aimed at exploring authenticity as a tool through which new technologies can effectively mediate a sense of place and foster brand communication of a destination. The case study is the UNESCO site of Tarragona whose most relevant image for urban policies is presented. This shared figuration spatially defined and rooted in a precise historical moment is reconstructed on the one hand through the analysis of functional documentation for the candidacy and on the other by means of a review of mobile applications developed for the promotion of the city's cultural heritage. The proposed journey and exploration of the place return in light of the research data and in conclusion the central role played by digital technologies in mediating the UNESCO imaginary. The forms of virtual tourism in Tarragona confirm that to travel is to experience a text enveloped in time and inscribed in space.Settore M-GGR/01 - Geografia
researchProduct

Oligodendrocyte ablation triggers central pain independently of innate or adaptive immune responses in mice.

2014

Mechanisms underlying central neuropathic pain are poorly understood. Although glial dysfunction has been functionally linked with neuropathic pain, very little is known about modulation of pain by oligodendrocytes. Here we report that genetic ablation of oligodendrocytes rapidly triggers a pattern of sensory changes that closely resemble central neuropathic pain, which are manifest before overt demyelination. Primary oligodendrocyte loss is not associated with autoreactive T- and B-cell infiltration in the spinal cord and neither activation of microglia nor reactive astrogliosis contribute functionally to central pain evoked by ablation of oligodendrocytes. Instead, light and electron micr…

NociceptionSpinothalamic tractSpinal Cord Dorsal HornSpinothalamic TractsT-LymphocytesGeneral Physics and AstronomyAdaptive ImmunityGeneral Biochemistry Genetics and Molecular BiologyArticleMicemedicineAnimalsOligodendrocyte; central painB-LymphocytesMultidisciplinaryMicrogliabusiness.industryGeneral Chemistrymedicine.diseaseSpinal cordOligodendrocyteAxonsImmunity InnateAstrogliosisMicroscopy ElectronOligodendrogliamedicine.anatomical_structureNociceptionSpinal CordAstrocytesNeuropathic painNeuralgiaNeuralgiaMicrogliabusinessNeuroscienceNature communications
researchProduct

Fundamental Research in Oncology and Thrombosis 2 (FRONTLINE 2): A Follow‐Up Survey

2020

Abstract Background Fundamental Research in Oncology and Thrombosis (FRONTLINE) is a global survey of physicians' perceptions and practice in the management of venous thromboembolism (VTE) in patients with cancer. Materials and Methods The present survey, FRONTLINE 2, follows the original FRONTLINE survey (published in The Oncologist in 2003) and provides insights into how physicians perceive risk of VTE in cancer and approach its prophylaxis and treatment. Results Between November 2015 and February 2016, 5,233 respondents participated, representing cancer physicians and surgeons. Most believed that less than one in five patients with any cancer might be at risk of VTE, with a slightly high…

OncologyCancer Researchmedicine.medical_specialtymedicine.drug_classmedicine.medical_treatment26030204 cardiovascular system & hematologyFondaparinuxDabigatranVenous thromboembolism • Cancer-associated thrombosis • Deep vein thrombosis • Pulmonary embolism • Central venous catheter.03 medical and health sciences0302 clinical medicineInternal medicineSurveys and QuestionnairesVenous thromboembolism • Cancer‐associated thrombosis • Deep vein thrombosis • Pulmonary embolism • Central venous cathetermedicineHumansRivaroxabanbusiness.industryAnticoagulantWarfarinCancerAnticoagulantsThrombosisVenous ThromboembolismHeparin Low-Molecular-Weightmedicine.diseasePulmonary embolismOncologySymptom Management and Supportive Care030220 oncology & carcinogenesisbusinessCentral venous cathetermedicine.drugFollow-Up StudiesThe Oncologist
researchProduct

Elimination of Established Risk-Factors in Primary Central Nervous System Lymphoma - Impact of High-Dose Chemotherapy Followed by Autologous Stem-Cel…

2011

Abstract Abstract 3089 Introduction: High-dose chemotherapy (HDT) and autologous stem-cell transplantation (ASCT) demonstrated high efficacy in the treatment of newly-diagnosed primary CNS lymphoma (PCNSL) in eligible patients (pts). Prognosis of PCNSL is associated with several clinical and histopathological risk factors (RF). Early complete response (CR) during chemotherapy (CHT) was recently reported to be an additional independent prognostic factor in pts undergoing polychemotherapy without HDT+ASCT. In this analysis, we examined the extent to which known RF determined survival in pts who were treated with HDT-ASCT. We additionally investigated the impact of HDT-ASCT specific factors (e…

Oncologymedicine.medical_specialtyChemotherapyPerformance statusbusiness.industryProportional hazards modelmedicine.medical_treatmentImmunologyPrimary central nervous system lymphomaCell BiologyHematologyThioTEPAmedicine.diseaseBiochemistryChemotherapy regimenSurgeryTransplantationInternal medicineMedicineStem cellbusinessmedicine.drugBlood
researchProduct

The largest bilateral gemination of permanent maxillary central incisors: report of a case

2013

Gemination is defined as an attempt to make two teeth from one enamel organ. Bilateral presentation of this phenomenon is very rare, with prevalence of 0.01% to 0.04% in the primary, and 0.05% in the permanent dentition. This paper describes a rare case of huge bilateral gemination of permanent maxillary central incisors in a nine-year-old Iranian boy with poor aesthetic. The patient did not have history of anomaly in his primary dentition and in his family either. This type of dental anomaly can cause clinical problems in the form of malocclusion, poor aesthetic, and impaction of adjacent teeth, caries, and periodontal destruction. Key words:Gemination, central incisor, bilateral.

Oral Medicine and PathologyDentitionbusiness.industryImpactionPermanent dentitionEnamel organDentistryCase ReportOdontologíamedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludstomatognathic diseasesstomatognathic systemGeminationUNESCO::CIENCIAS MÉDICASMedicineMaxillary central incisorPresentation (obstetrics)MalocclusionbusinessGeneral Dentistry
researchProduct

Relationship between pulp-tooth volume ratios and chronological age in different anterior teeth on CBCT

2017

Background The CBCT imaging technique exhibits proper accuracy to determine the internal anatomy of teeth. Therefore, this technique can use to estimate age by measuring the amount of decrease in the volume of the pulpal cavity of teeth. The aim of the present study was to evaluate the correlation between chronological age and pulp-to-tooth volume ratios in anterior teeth with the use of the CBCT technique and to determine a regression model to estimate human age. Material and methods In this present descriptive-analytical study, 122 subjects (46 males and 76 females), with an age range of 13-70 years, were evaluated. The MIMICS software program was used to determine the pulp-to-tooth volum…

Oral Medicine and Pathologybusiness.industryResearchForensic dentistryDentistryRegression analysis030206 dentistryChronological age:CIENCIAS MÉDICAS [UNESCO]03 medical and health sciencesstomatognathic diseases0302 clinical medicinemedicine.anatomical_structurestomatognathic systemAge estimationUNESCO::CIENCIAS MÉDICASDentinMedicinePulp (tooth)Maxillary central incisor030216 legal & forensic medicinebusinessGeneral DentistryAnterior teethJournal of Clinical and Experimental Dentistry
researchProduct

Adenomatoid odontogenic tumor : case series of 14 with wide range of clinical presentation

2017

Background To present 14 cases of adenomatoid odontogenic tumor (AOT), highlighting their clinical, radiographic, and histologic characteristics. Material and Methods Fourteen cases of AOT were retrieved from the archives of the Oral Pathology Biopsy Service (OPBS). Clinical, radiologic, and histologic findings are described. Results Fourteen AOT cases were reviewed, of which 12 were intraosseous and two were peripheral (gingiva). The cases came from eight females and six males with an age range of 11-30. Of the 12 intraosseous cases, nine were follicular (associated with impacted teeth), while three were extra-follicular (present between teeth). Six of the 12 cases were in the maxilla, and…

Oral Medicine and Pathologymedicine.diagnostic_testbusiness.industryAdenomatoid odontogenic tumorRadiographyResearchMandibleDentistry030206 dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Dentigerous cyst03 medical and health sciencesstomatognathic diseases0302 clinical medicinestomatognathic system030220 oncology & carcinogenesisMaxillaOral and maxillofacial pathologyBiopsyUNESCO::CIENCIAS MÉDICASmedicineMaxillary central incisorbusinessGeneral Dentistry
researchProduct

Miniscrew-supported distal jet versus conventional distal jet appliance: A pilot study

2019

Background Maxillary molar distalization is the most frequently used nonextraction treatment in the correction of Class II malocclusion. The use of traditional intra-oral devices shows unreliable results. Nowadays the use of miniscrew-supported appliances helps prevent anchorage loss. The aim of this pilot study is to compare the amount of upper first molar distalization and the dentoalveolar side effects using traditional distal jet appliance and miniscrew-supported distal jet appliance. Material and methods 20 patients were randomly assigned to receive a treatment with miniscrew-supported distal jet appliance (Group A) or with traditional distal jet appliance (Group B). To ensure a safe a…

Orthodontics3d printedJet (fluid)3D printed surgical guide; distal jet appliance; miniscrew; molar distalization; skeletal anchoragebusiness.industryResearchLateral cephalogramsOrthodontics030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseMandibular first molar03 medical and health sciences0302 clinical medicinestomatognathic systemUNESCO::CIENCIAS MÉDICASMaxillary first molarmedicineMaxillary molarMaxillary central incisor030212 general & internal medicineMalocclusionbusinessGeneral DentistryJournal of Clinical and Experimental Dentistry
researchProduct