Search results for " Character"

showing 10 items of 1756 documents

Insight into the molecular sex dimorphism of ischaemic stroke in rat cerebral cortex: Focus on neuroglobin, sex steroids and autophagy

2020

Including sex is of paramount importance in preclinical and clinical stroke researches, and molecular studies dealing in depth with sex differences in stroke pathophysiology are needed. To gain insight into the molecular sex dimorphism of ischaemic stroke in rat cerebral cortex, male and female adult rats were subjected to transient middle cerebral artery occlusion. The expression of neuroglobin (Ngb) and other functionally related molecules involved in sex steroid signalling (oestrogen and androgen receptors), steroidogenesis (StAR, TSPO and aromatase) and autophagic activity (LC3B-II/LC3B-I ratio, UCP2 and HIF-1 alpha) was assessed in the ipsilateral ischaemic and contralateral non-ischae…

Malemedicine.medical_specialtysteroidogenesisNeuroprotectionBrain IschemiaRats Sprague-Dawley03 medical and health sciences0302 clinical medicineInternal medicineCortex (anatomy)sex steroid signallingmedicineAutophagyAnimalssex dimorphismAromataseStroke030304 developmental biologyIschemic StrokeCerebral Cortex0303 health sciencesSex Characteristicsischaemic strokebiologybusiness.industryGeneral NeuroscienceInfarction Middle Cerebral Arterymedicine.diseaseRatsAndrogen receptorStrokeDisease Models AnimalneuroglobinEndocrinologymedicine.anatomical_structureSex steroidCerebral cortexNeuroglobinbiology.proteinFemaleSteroidsbusiness030217 neurology & neurosurgery
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CBCT location of the fusion between the buccal and lingual cortical in the mandibular ramus : importance to sagittal split osteotomy

2016

Background Mandibular Sagittal Split Osteotomy (MSSO) is a popular technique in orthognathic surgery used both to advance and to retreat the mandible. However, MSSO may incur in important complications, such as bad splits and sensorineural injuries. Knowing the location of the fusion between the buccal and lingual cortical (FBLC) in the mandibular ramus and the bone thickness in the region where osteotomies will be performed is determinant in MSSO planning to avoid complications. The aim of this study was to document and evaluate possible differences between sexes regarding the location of the FBLC in relation to the superior cortical of mandibular foramen (MF) and bone thickness in the reg…

Malemedicine.medical_treatmentOsteotomy Sagittal Split RamusOrthognathic surgeryDentistryMandibular canalSagittal split osteotomyMandibleMandibular second molarYoung Adult03 medical and health sciences0302 clinical medicineTonguestomatognathic systemRegion of interestHumansMedicineGeneral DentistryMouthSex Characteristicsbusiness.industryResearchMandibular foramen030206 dentistryBuccal administrationTOMOGRAFIA COMPUTADORIZADA POR RAIOS XCone-Beam Computed Tomography:CIENCIAS MÉDICAS [UNESCO]stomatognathic diseasesmedicine.anatomical_structureOtorhinolaryngology030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASFemaleSurgeryOral SurgerybusinessBrazilMandibular ramus
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Low back pain during military service predicts low back pain later in life

2016

The aim of the present study was to assess associations between physician diagnosed unspecified low back pain (LBP) during compulsory military service and self-reported LBP and physical fitness measured on average four years after military service. From a total of 1155 persons who had been pass medical examination for military service and who had completed physically demanding military training between 1997 and 2007, 778 men participated in a refresher military training course and physical tests. In this study, the association between LBP during military service and LBP in later life in addition to the association between LBP and physical fitness were examined. A total of 219 out of 778 par…

Malemilitary serivicesMedical DoctorsHealth Care ProvidersPhysical fitnesslcsh:MedicineMusculoskeletal symptomPathology and Laboratory Medicine0302 clinical medicineRisk FactorsMedicine and Health SciencesComputingMilieux_COMPUTERSANDEDUCATIONEthnicitiesPublic and Occupational Health030212 general & internal medicinelcsh:Scienceta315Musculoskeletal Systemlow back painMultidisciplinarypathological conditions signs and symptomspuolustusvoimatLow back painProfessionsMilitary personnelMilitary PersonnelLegsselkäpopulation characteristicsAnatomymedicine.symptomBehavioral and Social Aspects of HealthResearch ArticleAdultmedicine.medical_specialtyAdolescentMilitary serviceLower Back PainKirurgia anestesiologia tehohoito radiologia - Surgery anesthesiology intensive care radiologyPainback pain03 medical and health sciencesSigns and SymptomsDiagnostic MedicineselkäsairaudetPhysicianshealth services administrationIntensive careAnesthesiologymedicineHumansRisk factorbusiness.industryLimbs (Anatomy)lcsh:RBiology and Life ScienceskipuPhysical Activitynervous system diseasesHealth Carebody regionsPhysical FitnessPeople and PlacesPhysical therapyPopulation Groupingslcsh:QbusinessFinns030217 neurology & neurosurgeryFollow-Up StudiesPLOS ONE
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Tophaceous gout in the elderly: A clinical case review

2012

Gout is the most common cause of arthritis in the elderly. Its incidence among older people has risen worldwide due to an increase in risk factors such as renal diseases, metabolic syndrome, and a diet rich in purines. In older age, tophaceous gout may affect different joints from its classical presentation, due to other concomitant musculoskeletal diseases, but specific data on its epidemiology and clinical aspects in the elderly are limited to a few case reports. The present review focuses on the distinctive aspects of tophaceous gout in the elderly, revisiting all our clinical cases seen from 1990 to December 2011. Our findings indicate that: tophaceous gout can affect several joints in …

Malemusculoskeletal diseasesmedicine.medical_specialtyPediatricsGoutArthritisTophaceous goutRheumatologyRisk FactorsInternal medicineEpidemiologymedicineHumansAgedAged 80 and overSex CharacteristicsArthritis Goutybusiness.industryChronic gout Elderly Gender difference TophiIncidence (epidemiology)General Medicinemedicine.diseasehumanitiesRheumatologyGoutPhysical therapyFemaleMetabolic syndromebusinessSex characteristics
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Neighborhood Built Environment and Socioeconomic Status are Associated with Active Commuting and Sedentary Behavior, but not with Leisure-Time Physic…

2019

The role of neighborhood characteristics in promoting physical activity and sedentary behaviors (SB) has not been extensively studied in university students. The study purpose was to analyze the associations of neighborhood built environment and neighborhood socioeconomic status (SES) with active commuting, leisure-time physical activity (LTPA), and SB among university students. This is a cross-sectional study of 308 undergraduate students from two urban universities in Valencia, Spain. Participants&rsquo

MaleobesityHealth Toxicology and MutagenesisLeisure timelcsh:MedicineTransportationWalkingSocial Environment0302 clinical medicineResidence CharacteristicsSurveys and Questionnairesactive transportation030212 general & internal medicineBuilt EnvironmentBuilt environmentResidential environmentexerciseSedentary behaviorMiddle AgedWalkabilitypopulation characteristicsFemaleEducació físicaPsychologyAdultUniversitieseducationPhysical activityArticle03 medical and health sciencesYoung AdultHumansStudentsSocioeconomic statuswalkabilitylcsh:RSociologia urbanaPublic Health Environmental and Occupational Healthcollege students030229 sport sciencessocial sciencesurban environmentCross-Sectional StudiesResidential densitySocial ClassSpainGeographic Information SystemsRecreationSedentary Behaviorhuman activitiesDemographyInternational Journal of Environmental Research and Public Health
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Cross-sectional associations between the diversity of sport activities and the type of low back pain in adulthood

2020

Leisure-time physical activity has a complex relationship with low back pain (LBP). Thus, we aimed to investigate whether the diversity of sport activities is associated with the type of LBP. In the FinnTwin16 study, 4246 (55% females) Finnish twins at mean age 34.1 years replied to a health behaviour survey in 2010-2012. Based on the participation in different sport activities, we created two measures of diversity: quantity (i.e. the number of sport activities: 1, 2, 3, 4 and >= 5) and quality (i.e. the type of sport activity: endurance, strength, body care, etc.). Based on the frequency, duration and type of LBP, we created three groups: no history of LBP lasting more than one day, radiat…

Malephysical activitylumbagoliikuntaLogistic regressionRunning0302 clinical medicineOdds RatioOrthopedics and Sports Medicinekohorttitutkimuslow back painexerciseConfoundingGeneral MedicineLow back pain3142 Public health care science environmental and occupational healthPREVALENCEpopulation characteristicsselkäFemalemedicine.symptomCohort studyfyysinen aktiivisuusSportsCohort studyAdultmedicine.medical_specialtyPhysical activity030209 endocrinology & metabolismPhysical Therapy Sports Therapy and Rehabilitationiskias03 medical and health sciencesSex FactorsDiseases in Twinsmedicinecohort studyHumanssciaticabusiness.industryDISABILITYHealth behaviourkipu030229 sport sciencesOdds ratioBicyclingnervous system diseasesLogistic ModelsPHYSICAL-ACTIVITYPhysical EndurancePhysical therapybusinesshuman activitiesDiversity (business)
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Perception of Dating Violence in Teenage Couples: A Cross Validation Study in Spain and Colombia

2020

Background: dating violence, or violence in teenage couples, is a socially interesting topic, due to its prevalence and its possible use in predicting violence in adult couples. The perception of violence, or the detection of abusive behaviors by teenagers and young people (which can be considered as equivalent concepts), is essential to prevent violence itself. Therefore, the main objective of this research is to determine which behaviors are identified as abusive by teenagers and young people, and the severity that they attribute to them&mdash

Malerisk profilesAdolescentHealth Toxicology and Mutagenesismedia_common.quotation_subjectPsychological interventionlcsh:MedicineIntimate Partner Violence050109 social psychologySample (statistics)dating violenceColombiaSocial issuesAdolescentsArticleDevelopmental psychologySex FactorsPerceptionSurveys and QuestionnairesHumans0501 psychology and cognitive sciencesInterpersonal RelationsInternal validityPsychological abusemedia_commonFamily Characteristics05 social scienceslcsh:RPublic Health Environmental and Occupational HealthCountry of originTest (assessment)SpainFemaleadolescencesexismViolència juvenilPsychology050104 developmental & child psychology
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Contrasting parental roles shape sex differences in poison frog space use but not navigational performance

2022

Sex differences in vertebrate spatial abilities are typically interpreted under the adaptive specialization hypothesis, which posits that male reproductive success is linked to larger home ranges and better navigational skills. The androgen spillover hypothesis counters that enhanced male spatial performance may be a byproduct of higher androgen levels. Animal groups that include species where females are expected to outperform males based on life-history traits are key for disentangling these hypotheses. We investigated the association between sex differences in reproductive strategies, spatial behavior, and androgen levels in three species of poison frogs. We tracked individuals in natura…

Malesammakotsukupuolierotpaikkatietoanalyysi000 Computer science knowledge & systemseläinten käyttäytyminenGeneral Biochemistry Genetics and Molecular BiologyAnimals; Male; Female; Sex Characteristics; Poisons; Androgens; Anura; Spatial NavigationSex Factorsddc:630Animals000 Informatik Wissen SystemeGeneral Immunology and MicrobiologylisääntymiskäyttäytyminenBehavior AnimalGeneral NeuroscienceGeneral Medicineddc:elinpiirit (biologia)adaptive specialization hypothesis ; Allobates femoralis ; amphibians ; Dendrobates tinctorius ; ecology ; evolutionary biology ; Oophaga sylvatica ; testosterone spilloverAndrogens570 Life sciences; biology590 Animals (Zoology)FemaleAnura570 Biowissenschaften; Biologie
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The Independent Effects of Psychosocial Stressors on Subclinical Psychosis: Findings from the Multinational EU-GEI Study

2021

The influence of psychosocial stressors on psychosis risk has usually been studied in isolation and after the onset of the disorder, potentially ignoring important confounding relationships or the fact that some stressors that may be the consequence of the disorder rather than preexisting. The study of subclinical psychosis could help to address some of these issues. In this study, we investigated whether there was (i) an association between dimensions of subclinical psychosis and several psychosocial stressors including: childhood trauma, self-reported discrimination experiences, low social capital, and stressful life experiences, and (ii) any evidence of environment-environment (ExE) inte…

Malestressful life eventsSchizotypypositive subclinical symptomEthnic groupSocial Environmentsubclinical psychosispositive subclinical symptoms0302 clinical medicineAdverse Childhood ExperiencesSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.SINTOMAS PSÍQUICOSsubclinical psychosi10. No inequalityCOMMUNITY ASSESSMENTSubclinical infectionGENERAL-POPULATIONpsychotic symptomDepressionConfoundingSocial Discriminationdepressive subclinical symptomstressful life eventETHNIC-GROUPS3. Good healthPsychiatry and Mental healthNEIGHBORHOOD CHARACTERISTICSADULT PSYCHIATRIC-DISORDERSpsychotic symptomsAdverse Childhood ExperienceFemalepsychosocial stressPsychologyPsychosocialHumanClinical psychologynegative subclinical symptompsychosocial streAdultPsychosisSiblingLIFE EVENTSschizotypyPsychotic Disorder03 medical and health sciencesCommunity Assessment of Psychic Experiences (CAPE)THREATENING EXPERIENCESmedicineHumansEuropean UnionSiblingSettore MED/25 - Psichiatriachildhood traumaSiblingsStressormedicine.diseasePERCEIVED DISCRIMINATIONnegative subclinical symptoms030227 psychiatryPSYCHOMETRIC PROPERTIESPsychotic Disorders[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental healthdis criminationsocial capitaldepressive subclinical symptomsStress Psychological030217 neurology & neurosurgeryRegular Articlesdiscrimination
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Pan-cancer analysis of whole genomes

2020

Publisher's version (útgefin grein)

Maletert promoter mutationsCancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2]DNA Mutational AnalysisNormal tissuesystematic analysisGermlineTranscriptome0302 clinical medicineAetiologyCàncerCellular SenescenceCancer0303 health sciencesdna-damageMassive parallel sequencingPan cancerREARRANGEMENTSHigh-Throughput Nucleotide SequencingGenomicsSciences bio-médicales et agricolesTelomereCOMPREHENSIVE3. Good healthTERT PROMOTER MUTATIONSsignatures030220 oncology & carcinogenesisScience & Technology - Other TopicsErfðarannsóknirHuman:Informàtica::Aplicacions de la informàtica::Bioinformàtica [Àrees temàtiques de la UPC]EvolutionRNA SplicingGenomicsArticleEvolution MolecularStructural variationRC025403 medical and health sciencesSDG 3 - Good Health and Well-beingGeneticgenomicsSYSTEMATIC ANALYSISGeneticsGenomics--Databases.HumansGenetic TestingMolecular BiologySIGNATURESWhole genome sequencing1000 MultidisciplinaryChromothripsisScience & TechnologyRC0254 Neoplasms. Tumors. Oncology (including Cancer)Information DisseminationResearchInstitutes_Networks_Beacons/mcrcPreventionBiology and Life SciencesMolecularOncogenesCloud Computingmedicine.diseaseGenòmicaCompute cloudsMutation570 Life sciences; biologyCOMPREHENSIVE CHARACTERIZATIONGenèticaWhole Genome Sequencing--methodsBackground informationDNA Mutational Analysis ; Evolution ; Genetic / genetics ; Genome ; Genomics ; Germ-Line Mutation / genetics ; High-Throughput Nucleotide Sequencing ; Human / genetics ; Humans ; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumMedizinGenomeWhole-genomeGenome mappingNeoplasms2.1 Biological and endogenous factorsPromoter Regions GeneticCàncer -- Aspectes genèticsTelomeraseGeneticsWomen's cancers Radboud Institute for Molecular Life Sciences [Radboudumc 17]MultidisciplinaryChromothripsisGenomeManchester Cancer Research Centregenomics cancer profiling3rd-DAS10124 Institute of Molecular Life SciencesWomen's cancers Radboud Institute for Health Sciences [Radboudumc 17]Multidisciplinary SciencesParallel sequencingICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumFemaleprofilingMedical GeneticsEngineering sciences. TechnologyBiotechnologyGeneral Science & TechnologyThe Cancer Genome Atlas610 Medicine & healthComputational biologyQH426 GeneticsBiologyConsortium of the International Cancer Genome ConsortiumPromoter RegionsGermline mutationPan-cancer analysisKrabbameinsrannsóknirmedicinecancerddc:610QH426Germ-Line MutationMedicinsk genetikKrabbamein030304 developmental biologyCell ProliferationLANDSCAPEGenome Humancomprehensive characterizationPan-cancer analysis of whole genomesPoint mutationHuman GenomeCancerReproducibility of ResultsSOMATIC MUTATIONSEVOLUTIONCancer sequencing Chromothripsis telomereDNA-DAMAGEMutagenesisPATTERNS3111 BiomedicineCHARACTERIZATION
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