Search results for " Colon Cancer"

SICILIAN MANGO PEEL INDUCES CELLULAR STRESS ACCOMPANIED TO MITOCHONDRIAL DYSFUNCTION IN COLON CANCER CELLS

2021

Currently, cellular stresses as the oxidative, metabolic and genotoxic stress are considered the cause of many different human pathologies as neurodegenerative diseases (e.g.,Alzheimer’s, Parkinson’s, amyotrophic lateral sclerosis), alcoholic liver disease, chronic obstructive pulmonary disease, and also cancer. Although the role of cellular stress has been largely debated in cancer, nowadays some therapies aim to target the intracellular pro-oxidant/anti-oxidant balance triggering the tumor commitment to cell death. Therefore, it has become more necessary an improved understanding of cancer response to cellular stress that could be advantageous to develop cancer tailored therapies. In this…