Search results for " Color"

showing 10 items of 770 documents

Reduced-dose of doublet chemotherapy combined with anti-EGFR antibodies in vulnerable older patients with metastatic colorectal cancer: Data from the…

2022

Abstract Objectives To assess the toxicity patterns and effectiveness of doublet chemotherapy when administered at reduced doses of 20% (FOLFOX or FOLFIRI) in combination with anti-EGFR antibodies (cetuximab or panitumumab) in old, vulnerable patients with metastatic colorectal cancer (mCRC). Patients and methods We performed a retrospective observational study of RAS and BRAF wild-type, vulnerable patients aged ≥70 years with previously untreated mCRC. The primary endpoint was safety, and secondary endpoints were overall response rate (ORR), progression-free survival (PFS), and overall survival (OS). Results One hundred and eighteen patients were collected from 14 selected Italian centres.…

medicine.medical_specialtyReduced doseColorectal cancerLeucovorinCetuximabNeutropeniaGastroenterologyFOLFOXInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineClinical endpointHumansPanitumumabDoublet chemotherapyAnti-EGFRAgedCetuximabMetastatic colorectal cancerRectal Neoplasmsbusiness.industryPanitumumabAnti-EGFRs Doublet chemotherapy Metastatic colorectal cancer Reduced doses Vulnerable older patientsExanthemamedicine.diseaseRashVulnerable older patients.OncologyColonic NeoplasmsFOLFIRIFluorouracilGeriatrics and Gerontologymedicine.symptomColorectal Neoplasmsbusinessmedicine.drugJournal of Geriatric Oncology
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Expression pattern of receptor activator of NFκB (RANK) in a series of primary solid tumors and related bone metastases.

2011

Receptor activator of NFκB ligand (RANKL), RANK, and osteoprotegerin (OPG) represent the key regulators of bone metabolism both in normal and pathological conditions, including bone metastases. To our knowledge, no previous studies investigated and compared RANK expression in primary tumors and in bone metastases from the same patient. We retrospectively examined RANK expression by immunohistochemistry in 74 bone metastases tissues from solid tumors, mostly breast, colorectal, renal, lung, and prostate cancer. For 40 cases, tissue from the corresponding primary tumor was also analyzed. Sixty-six (89%) of the 74 bone metastases were RANK-positive and, among these, 40 (59.5%) showed more than…

medicine.medical_specialtySettore MED/06 - Oncologia MedicaPhysiologyClinical Biochemistrycolorectal cancerBone NeoplasmsBone remodelingMetastasisProstate cancerbreast cancerOsteoprotegerinInternal medicinemedicineHumansbone metastasibiologyReceptor Activator of Nuclear Factor-kappa Bbusiness.industryMedicine (all)Bone metastasisCell Biologymedicine.diseasePrimary tumorbone metastasis; breast cancer; colorectal cancerImmunohistochemistryEndocrinologyBone Neoplasms; Humans; Immunohistochemistry; Receptor Activator of Nuclear Factor-kappa B; Medicine (all); Physiology; Clinical Biochemistry; Cell BiologyRANKLCancer researchbiology.proteinImmunohistochemistrybusinessJournal of cellular physiology
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Milestones in robotic colorectal surgery development: an historical overview

2020

The present article is a historical review intended to trace the most important phases in the development of robotic surgical technology, with a special focus on colorectal surgery. The initial section considers the origin and some etymological aspects of the word “robot”. Then, a historical overview traces the development of robotic technology in industry and its implementation within the operating theatres. Finally, the first publications concerning robot-assisted colon and rectal surgery are reported together with a brief state of the art about this issue.

medicine.medical_specialtySettore MED/18 - Chirurgia Generalebusiness.industryGeneral surgerymedicineRobotic surgeryRobotic surgery colorectal surgery historybusinessColorectal surgery
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Toothguide Training Box for Dental Color Choice Training

2011

The purpose of this study was to evaluate the use of the Toothguide Training Box (TTB) for training dental students in color identification. The seventy-four volunteers who took part in the study attended a seminar on the Vita 3D Master Guide (MG) and the TTB system as well as a demonstration of the equipment before training began. At the end of the training they took the TTB final test. In addition, the participants were asked to recognize ten MG shade tabs in a blind manner before and after TTB training. The training times and percentages of correct answers were compared using the paired t-test. Variations in scores with training times and percentages of correct answers before and after t…

medicine.medical_specialtyTime FactorsAudiovisual AidsProsthesis Coloringbusiness.industryeducationAnova testTraining (meteorology)DentistryEquipment DesignGeneral MedicineEsthetics DentalPositive correlationChoice BehaviorTest (assessment)Young AdultMicrocomputersPhysical therapymedicineHumansEducational MeasurementbusinessPsychologyEducation DentalLighting
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Screening of colorectal cancer: present and future

2017

Colorectal cancer (CRC) is the third most common cancer in males and second in females, and the fourth most common cause of cancer death worldwide. Currently, about 60-70% of diagnosed cases in symptomatic patients are detected at an advanced stage of disease. Earlier stage detection through the use of screening strategies would allow for better outcomes in terms of reducing the disease burden. Areas covered: The aim of this paper is to review the current published evidence from literature which assesses the performance and effectiveness of different screening tests for the early detection of CRC. Expert commentary: Adequate screening strategies can reduce CRC incidence and mortality. In th…

medicine.medical_specialtyTime FactorsColorectal cancerSettore MED/12 - GASTROENTEROLOGIAEarly detectionDisease03 medical and health sciences0302 clinical medicinemedicineHumansMass ScreeningPharmacology (medical)Stage (cooking)Intensive care medicineEarly Detection of CancerNeoplasm StagingGynecologygFOBTCrc screeningbusiness.industryIncidence (epidemiology)screeningAdvanced stageCancerColonoscopycolonscopymedicine.diseaseFITColorectal cancercolonscopy; Colorectal cancer; FIT; gFOBT; screening; surveillance; Colonoscopy; Colorectal Neoplasms; Early Detection of Cancer; Humans; Mass Screening; Neoplasm Staging; Practice Guidelines as Topic; Time Factors; Oncology; Pharmacology (medical)Oncology030220 oncology & carcinogenesisPractice Guidelines as Topicsurveillance030211 gastroenterology & hepatologybusinessColorectal Neoplasms
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Recommendations for Multimodal Noninvasive and Invasive Screening for Detection of Extracranial Venous Abnormalities Indicative of Chronic Cerebrospi…

2014

Under the auspices of the International Society for Neurovascular Disease (ISNVD), four expert panel committees were created from the ISNVD membership between 2011 and 2012 to determine and standardize noninvasive and invasive imaging protocols for detection of extracranial venous abnormalities indicative of chronic cerebrospinal venous insufficiency (CCSVI). The committees created working groups on color Doppler ultrasound (US), magnetic resonance (MR) imaging, catheter venography (CV), and intravascular US. Each group organized a workshop focused on its assigned imaging modality. Non-ISNVD members from other societies were invited to contribute to the various workshops. More than 60 neuro…

medicine.medical_specialtyVascular MalformationsVenographyVertebral veinMultimodal ImagingNOmedicineHumansRadiology Nuclear Medicine and imagingVascular DiseasesUltrasonography Doppler ColorUltrasonography Interventionalmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingInterventional radiologyPhlebographyVascular surgeryNeurovascular bundlemedicine.diseaseMagnetic Resonance ImagingCerebrovascular DisordersCatheterChronic cerebrospinal venous insufficiencyVenous InsufficiencyRadiology Nuclear Medicine and imagingRadiologybusinessCardiology and Cardiovascular MedicineJournal of Vascular and Interventional Radiology
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Photoaging evaluation by RGB images using a smartphone for photodynamic therapy assessment

2017

In this study was evaluated the photoaging of patients' skins by the processing of RGB images acquired with an optical system based on a smartphone. Two groups were approached: a younger and an older.

medicine.medical_specialtybusiness.industrymedicine.medical_treatmentPhotoagingPhotodynamic therapyImage processingmedicine.diseaseDermatologyReflectivitymedicineRGB color modelComputer visionArtificial intelligencebusiness
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Histology and Fine Structure of the Iris and Outflow System Following Latanoprost Therapy

2002

Latanoprost therapy can lead to iris darkening in susceptible individuals, particularly those with hazel eyes. Concerns have been raised about whether latanoprost, and for that matter other prostanoids, may have a harmful effect on the iris. In addition, it is unknown whether latanoprost causes increased pigmentation of the outflow pathways that might eventually lead to blockage and a type of pigmentary glaucoma. The present study summarizes findings from the authors' own laboratories on the effects of latanoprost as seen by light and electron microscopy of the iris and outflow tissues and reviews the as yet limited, relevant literature. The findings support the proposal that latanoprost-in…

medicine.medical_specialtygenetic structuresEye diseasemedicine.medical_treatmentIrisGlaucomaMelanocyteMelaninchemistry.chemical_compoundTrabecular MeshworkOphthalmologymedicineHumansTrabeculectomyIris (anatomy)LatanoprostAntihypertensive AgentsIntraocular PressureMelaninsEye Colorbusiness.industryfungiGlaucomamedicine.diseaseHyperpigmentationeye diseasesSurgeryOphthalmologymedicine.anatomical_structureIris DiseaseschemistryProstaglandins F SyntheticLatanoprostMelanocytessense organsmedicine.symptombusinessPigmentation DisordersSurvey of Ophthalmology
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Tree Species Identification Using 3D Spectral Data and 3D Convolutional Neural Network

2018

In this study we apply 3D convolutional neural network (CNN) for tree species identification. Study includes the three most common Finnish tree species. Study uses a relatively large high-resolution spectral data set, which contains also a digital surface model for the trees. Data has been gathered using an unmanned aerial vehicle, a framing hyperspectral imager and a regular RGB camera. Achieved classification results are promising by with overall accuracy of 96.2 % for the classification of the validation data set. nonPeerReviewed

medicine.medical_specialtyhahmontunnistus (tietotekniikka)010504 meteorology & atmospheric sciencesComputer scienceUAV0211 other engineering and technologiesconvolutional neural network02 engineering and technologyneuroverkot01 natural sciencesConvolutional neural networkpuulajitmedicine3D-mallinnusSpectral data021101 geological & geomatics engineering0105 earth and related environmental sciencesbusiness.industryspektrikuvausHyperspectral imagingPattern recognitionSpectral imagingRGB color modelArtificial intelligencebusinessDigital surfaceTree species3D
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RGB mapping of hemoglobin distribution in skin

2011

An experimental RGB imaging system based on commercial color camera was constructed, and its potential for mapping of hemoglobin distribution in skin was studied. Two types of LEDs (RGB and white “warm” LEDs) were compared as illuminators for acquiring images of vascular and pigmented skin malformations. A novel approach for studies of skin capillary refill by RGB analysis has been proposed and discussed.

medicine.medical_specialtyintegumentary systemmedicine.diagnostic_testComputer sciencebusiness.industryMultispectral imageSkin capillaryCapillary refilllaw.inventionSpectral imagingLED lampOpticslawmedicineRGB color modelComputer visionArtificial intelligencePigmented skinbusinessLight-emitting diode
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