Search results for " Combined Modality Therapy"

showing 6 items of 26 documents

Early endovascular aneurysm repair after percutaneous coronary interventions

2015

Objective The objective of this study was to report long-term results of early endovascular aortic aneurysm repair after percutaneous coronary intervention (PCI). Methods This was a retrospective analysis of all patients presenting with abdominal aortic aneurysm and coronary artery disease treated during the same hospitalization by endovascular aortic aneurysm repair performed soon after PCI. Primary outcomes were perioperative mortality, perioperative complications, survival after treatment, and freedom from reintervention. Results A total of 20 patients were included, and all completed both procedures. No deaths or abdominal aortic aneurysm ruptures occurred between the PCI and the aortic…

Malemedicine.medical_treatmentCoronary DiseaseComorbidityEndovascular aneurysm repairSettore MED/22 - Chirurgia VascolareCoronary artery diseaseAortic aneurysmPostoperative ComplicationsRisk FactorsRetrospective StudieCause of DeathMyocardial infarctionHospital MortalityAged; Aged 80 and over; Aortic Aneurysm Abdominal; Cause of Death; Combined Modality Therapy; Comorbidity; Coronary Disease; Follow-Up Studies; Hospital Mortality; Humans; Italy; Male; Middle Aged; Postoperative Complications; Reoperation; Retrospective Studies; Risk Factors; Survival Rate; Early Medical Intervention; Percutaneous Coronary Intervention; Cardiology and Cardiovascular Medicine; Surgery; Medicine (all)Aged 80 and overMedicine (all)Middle AgedCombined Modality TherapyAbdominal aortic aneurysm2746 SurgerySurvival RateItalycardiovascular systemCardiologyCardiology and Cardiovascular MedicineHumanReoperationmedicine.medical_specialty10216 Institute of Anesthesiology610 Medicine & health2705 Cardiology and Cardiovascular MedicineFollow-Up StudiePercutaneous Coronary InterventionInternal medicineEarly Medical InterventionmedicineHumanscardiovascular diseasesRetrospective StudiesAgedbusiness.industryRisk FactorPercutaneous coronary interventionPerioperativemedicine.disease10020 Clinic for Cardiac SurgerySurgeryConventional PCISurgeryPostoperative ComplicationbusinessFollow-Up StudiesAortic Aneurysm Abdominal
researchProduct

Minimally invasive secondary cytoreduction plus HIPEC for recurrent ovarian cancer: a case series.

2014

Objective To analyze the feasibility of laparoscopic/robotic secondary cytoreductive surgery and hyperthermic intraperitoneal intra-operative chemotherapy (SCS + HIPEC) in a retrospective series of isolated platinum sensitive recurrent ovarian cancer. Methods We retrospectively evaluated a consecutive series of ovarian cancer patients with isolated platinum sensitive relapse. Isolated relapse was defined as the presence of a single nodule, in a single anatomic site. In all cases the presence of isolated relapse was assessed at pre-operative FDG-PET/CT scan, and confirmed with staging laparoscopy performed immediately before SCS + HIPEC. Results 84 women with platinum sensitive relapse recei…

OVARIAN CANEROrganoplatinum Compoundsmedicine.medical_treatmentdrug therapy/pathology/surgery/therapyCarcinoma Ovarian EpithelialMultimodal ImagingCohort StudiesObstetrics and gynaecologyNeoplasmsAntineoplastic Combined Chemotherapy ProtocolsInfusions ParenteralNeoplasms Glandular and EpithelialLaparoscopyadministration /&/ dosageTomographyRandomized Controlled Trials as TopicOvarian Neoplasmsmedicine.diagnostic_testObstetrics and GynecologyGlandular and EpithelialMiddle AgedDebulkingCombined Modality TherapyIsolated platinum sensitive relapseX-Ray ComputedOxaliplatinPhase III as TopicOncologyFemalediagnostic usemedicine.drugmedicine.medical_specialtyInfusionsAged Antineoplastic Combined Chemotherapy Protocols; administration /&/ dosage Cisplatin; administration /&/ dosage Clinical Trials; Phase II as Topic Clinical Trials; Phase III as Topic Cohort Studies Combined Modality Therapy Female Fluorodeoxyglucose F18; diagnostic use Humans Hyperthermia; Induced; methods Infusions; Parenteral Middle Aged Minimally Invasive Surgical Procedures Multimodal Imaging Neoplasms; Glandular and Epithelial; drug therapy/pathology/surgery/therapy Organoplatinum Compounds; administration /&/ dosage Ovarian Neoplasms; drug therapy/pathology/surgery/therapy Positron-Emission Tomography Radiopharmaceuticals; diagnostic use Randomized Controlled Trials as Topic Retrospective Studies Tomography; X-Ray Computed ocal; pathologyocalmethodsClinical Trials Phase II as TopicMinimally invasive surgeryOvarian cancerFluorodeoxyglucose F18ParenteralmedicineHumansMinimally Invasive Surgical ProceduresClinical TrialsHyperthermiaAgedRetrospective StudiesCisplatinChemotherapySeries (stratigraphy)HIPECbusiness.industryPhase II as TopicInducedHyperthermia Inducedmedicine.diseaseOxaliplatinSurgeryRoboticSettore MED/40 - GINECOLOGIA E OSTETRICIAClinical Trials Phase III as TopicPositron-Emission TomographyLaparoscopypathologyNeoplasm Recurrence LocalCisplatinRadiopharmaceuticalsbusinessOvarian cancerTomography X-Ray Computed
researchProduct

Management and treatment of triple-negative breast cancer patients from the NEMESI study: An Italian experience

2011

Abstract Aims Triple-negative breast cancers (TNBCs) lack expression of oestrogen, progesterone, and Human Epidermal Growth Factor 2 receptors. The NEMESI study described current Italian treatment practices in patients with operable, early-stage breast cancer (EBC). Patients and methods Retrospective, observational study involving 63 Italian oncology centres. Eligible patients were aged ⩾18 years with EBC (stage I–II) who had undergone surgery, received ⩾1 cycle of adjuvant chemotherapy and/or adjuvant hormonal therapy and attended an oncology centre between 1 January 2008 and 30 June 2008. This subanalysis focused on patients with TNBC. Variables evaluated included: demographic data/clinic…

OncologyCancer ResearchSettore MED/06 - Oncologia MedicaReceptor ErbB-2receptormedicine.medical_treatmentreceptorsGuidelineClinical practicechemotherapyAntineoplastic Combined Chemotherapy ProtocolsestrogenMedicineStage (cooking)Triple-negative breast cancerAdjuvant therapy Clinical practice Guidelines Italy National register Triple-negative breast cancer --------------------------------------------------------------------------------Middle AgedCombined Modality TherapyReceptors EstrogenItalyOncologyChemotherapy AdjuvantHormonal therapyFemaleReceptors Progesteronemedicine.medical_specialtyNational registerBreast NeoplasmsprogesteroneGuidelinesAdjuvant therapyBreast canceradjuvantTriple-negative breast canceradjuvant therapy; clinical practice; guidelines; italy; national register; triple-negative breast cancer; aged; antineoplastic combined chemotherapy protocols; breast neoplasms; chemotherapy adjuvant; combined modality therapy; female; humans; italy; middle aged; radiotherapy adjuvant; receptor erbb-2; receptors estrogen; receptors progesterone; retrospective studiesInternal medicineAdjuvant therapyHumansradiotherapyAgedRetrospective StudiesChemotherapybusiness.industryTriple-negative breast cancer --------------------------------------------------------------------------------medicine.diseaseRadiation therapyAged Antineoplastic Combined Chemotherapy Protocols; therapeutic use Breast NeoplasmsRadiotherapy AdjuvantObservational studybusinesserbb-2
researchProduct

Economic evaluation of sublingual immunotherapy vs. symptomatic treatment in allergic asthma.

2009

Background The worldwide increased prevalence of allergic diseases, and especially of respiratory allergy, is paralleled by increased health costs. This requires consideration of the cost to efficacy ratio of the available treatment to identify the optimal choice. Objective To compare the different economic relevance, over a long evaluation time, of symptomatic pharmacologic therapy and sublingual immunotherapy (SLIT) in patients with allergic asthma. Methods Seventy patients with perennial allergic asthma, sensitized to dust mites, were enrolled; 50 of these patients were treated with SLIT against house dust mites and 20 were treated with symptomatic drugs. The patients were evaluated for …

Pulmonary and Respiratory MedicineAdultMalemedicine.medical_specialtyAllergyAdolescentCost-Benefit AnalysisImmunologyPopulationAdministration SublingualFollow-Up StudieSublingual administrationDrug TherapyImmunopathologyInternal medicinemedicineImmunology and AllergyHumansCost-Benefit AnalysieducationChildAsthmaeducation.field_of_studyDrug Therapy; Combined Modality Therapy; Immunotherapy; Humans; Asthma; Child; Health Care Costs; Cost-Benefit Analysis; Adult; Middle Aged; Follow-Up Studies; Adolescent; Administration Sublingual; Male; Femalebusiness.industryRespiratory diseaseHealth Care CostsMiddle Agedmedicine.diseaseSlitCombined Modality TherapyAsthmaSurgeryHealth Care CostObservational studyFemaleImmunotherapybusinessHumanFollow-Up StudiesAnnals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology
researchProduct

Surgical sphincter saving approach and topical nifedipine for chronic anal fissure with hypertonic internal anal sphincter

2020

PURPOSE The role of augmented internal anal sphincter (IAS) tone in the genesis of posterior chronic anal fissure (CAPF) is still unknown. Lateral internal sphincterotomy is the most employed surgical procedure, nevertheless it is burdened by high risk post-operative anal incontinence. The aim of our study is to evaluate results of sphincter saving procedure with post-operative pharmacological sphincterotomy for patients affected by CAPF with IAS hypertonia. Methods: We enrolled 30 patients, undergone fissurectomy and anoplasty with V-Y cutaneous flap advancement; all patients received topical administration of nifedipine 0.3% and lidocaine 1.5% ointment-based therapy before and for 15 days…

medicine.medical_specialtyLidocaineNifedipinemedicine.medical_treatmentAdministration TopicalAnal CanalSurgical FlapsInternal anal sphincterFissurectomyOintmentsMuscle HypertoniaNifedipineMuscle HypertoniamedicineHumansProspective StudiesAnesthetics LocalAnestheticsAnal fissureAnal fissure Anoplasty Fissurectomy Lidocaine Nifedipine Proctology Administration Topical Anal Canal Anesthetics Local Calcium Channel Blockers Chronic Disease Combined Modality Therapy Humans Lidocaine Muscle Hypertonia Ointments Prospective Studies Surgical Flaps Treatment Outcome Fissure in Ano Nifedipinebusiness.industryLidocaineAnal canalAnoplastymedicine.diseaseCalcium Channel BlockersCombined Modality TherapySurgerymedicine.anatomical_structureTreatment OutcomeTopicalLocalAdministrationChronic DiseaseHypertoniaSurgeryFissure in Anomedicine.symptomAnal fissureProctologyLateral internal sphincterotomybusinessmedicine.drug
researchProduct

Tubular carcinoma of the breast: Outcome and loco-regional recurrence in 307 patients

2005

Abstract Purpose The aim of this study is to describe the University of Florence experience in evaluating clinical, pathologic and treatment factors as they are related to the outcome and loco-regional recurrence in patients with tubular breast carcinoma. Material and methods Three hundred and seven patients (median age 56.4 years, range 26–91 years) with histological verified tubular carcinoma of the breast were consecutively treated at University of Florence from 1976 to 2001. All patients were followed for a median of 8.4 years (range 3 months to 20 years). Thirty-seven women underwent mastectomy and 270 underwent breast conserving surgery. Positive axillary nodes were found in 15% of pa…

medicine.medical_treatmentDiseaseSegmentalMastectomy SegmentalBreast cancerDuctalBreast-conserving surgery80 and overBreastAdjuvantMastectomyAged 80 and overCarcinoma Ductal BreastTubular carcinomaGeneral MedicineMiddle AgedCombined Modality TherapyTreatment OutcomeBreast cancer; Radiotherapy; Tubular carcinoma; Adenocarcinoma; Adult; Aged; Aged 80 and over; Antineoplastic Agents Hormonal; Axilla; Breast Neoplasms; Carcinoma Ductal Breast; Chemotherapy Adjuvant; Combined Modality Therapy; Female; Humans; Lymphatic Metastasis; Mastectomy; Mastectomy Segmental; Middle Aged; Neoplasm Recurrence Local; Proportional Hazards Models; Radiotherapy Adjuvant; Survival Analysis; Tamoxifen; Treatment Outcome; Oncology; SurgeryLocalOncologyChemotherapy AdjuvantLymphatic MetastasisFemaleMastectomymedicine.drugAdultmedicine.medical_specialtyAntineoplastic Agents HormonalAntineoplastic AgentsBreast NeoplasmsAdenocarcinomaBreast cancermedicineChemotherapyHumansAgedProportional Hazards ModelsChemotherapyRadiotherapyHormonalbusiness.industryCarcinomamedicine.diseaseSurvival AnalysisSurgeryRadiation therapyTamoxifenNeoplasm RecurrenceAxillaRadiotherapy AdjuvantSurgeryTubular carcinomaNeoplasm Recurrence LocalbusinessTamoxifen
researchProduct