Search results for " Consensus"
showing 10 items of 150 documents
Methods report on the development of the 2013 revision and update of the EAACI/GA2 LEN/EDF/WAO guideline for the definition, classification, diagnosi…
2014
GA2LEN EAACI This methods report describes the process of guideline development in detail. It is the result of a systematic literature review using the 'Grading of Recommendations Assessment, Development and Evaluation' (GRADE) methodology and a structured consensus conference held on 28 and 29 November 2012, in Berlin. It is a joint initiative of the Dermatology Section of the European Academy of Allergy and Clinical Immunology (EAACI), the EU-funded network of excellence, the Global Allergy and Asthma European Network (GA(2)LEN), the European Dermatology Forum (EDF), and the World Allergy Organization (WAO) with the participation of delegates of 21 national and international societies. Th…
Hepatocellular carcinoma: one world, one cancer—different guidelines?
2018
Hepatocellular carcinoma (HCC) is a healthcare challenge in virtually all parts of the world. Therefore, it is no wonder that different guidelines have been developed reflecting expert consensus on the management of HCC in different regions, namely guidelines from the American Association for the Study of Liver Diseases (AASLD) for the USA (1,2), the Asian Pacific Association for the Study of the Liver (APASL) for the Asia-Pacific region (3), the European Association for the Study of the Liver (EASL) for Europe (4), and the Japan Society of Hepatology (JSH) for Japan (5,6). In 2018 an update of the EASL clinical practice guidelines (CPG) will appear.
Fit-for-Discharge Criteria after Esophagectomy: An International Expert Delphi Consensus
2021
Summary There are no internationally recognized criteria available to determine preparedness for hospital discharge after esophagectomy. This study aims to achieve international consensus using Delphi methodology. The expert panel consisted of 40 esophageal surgeons spanning 16 countries and 4 continents. During a 3-round, web-based Delphi process, experts voted for discharge criteria using 5-point Likert scales. Data were analyzed using descriptive statistics. Consensus was reached if agreement was ≥75% in round 3. Consensus was achieved for the following basic criteria: nutritional requirements are met by oral intake of at least liquids with optional supplementary nutrition via jejunal fe…
Determination of the Time Window of Event-Related Potential Using Multiple-Set Consensus Clustering
2020
Clustering is a promising tool for grouping the sequence of similar time-points aimed to identify the attention blocks in spatiotemporal event-related potentials (ERPs) analysis. It is most likely to elicit the appropriate time window for ERP of interest if a suitable clustering method is applied to spatiotemporal ERP. However, how to reliably estimate a proper time window from entire individual subjects’ data is still challenging. In this study, we developed a novel multiset consensus clustering method in which several clustering results of multiple subjects were combined to retrieve the best fitted clustering for all the subjects within a group. Then, the obtained clustering was processed…
Determination of the Time Window of Event-Related Potential Using Multiple-Set Consensus Clustering
2020
Clustering is a promising tool for grouping the sequence of similar time-points aimed to identify the attention blocks in spatiotemporal event-related potentials (ERPs) analysis. It is most likely to elicit the appropriate time window for ERP of interest if a suitable clustering method is applied to spatiotemporal ERP. However, how to reliably estimate a proper time window from entire individual subjects’ data is still challenging. In this study, we developed a novel multiset consensus clustering method in which several clustering results of multiple subjects were combined to retrieve the best fitted clustering for all the subjects within a group. Then, the obtained clustering was processed…
Antineoplastic dosing in overweight and obese cancer patients: an Associazione Italiana Oncologia Medica (AIOM)/Associazione Medici Diabetologi (AMD)…
2021
Most anticancer molecules are administered in body-size-based dosing schedules, bringing up unsolved issues regarding pharmacokinetic data in heavy patients. The worldwide spread of obesity has not been matched by improved methods and strategies for tailored drug dosage in this population. The weight or body surface area (BSA)-based approaches may fail to fully reflect the complexity of the anthropometric features besides obesity in cancer patients suffering from sarcopenia. Likewise, there is a lack of pharmacokinetic data on obese patients for the majority of chemotherapeutic agents as well as for new target drugs and immunotherapy. Therefore, although the available findings point to the …
Genetic relationship between clinical and environmental Vibrio cholerae isolates in Tanzania: A comparison using repetitive extragenic palindromic (R…
2015
The bacterium causing cholera, Vibrio cholerae, is a marine organism and coastal waters are important reservoirs of the organism. There are more than 200 serogroups of V. cholerae, of which serogroups O1 and O139 are known to be the causative agent of the cholera. The main virulent factor in V. cholerae is cholera toxin gene (ctx) that is found from the epidemic O1 and O139 strains, but may also be found in some strains other than O1 and O139 (non-O1 and non-O139). In this study, 48 V. cholerae strains isolated from three estuaries of Tanzania and 20 stool isolates were characterized in terms of their serogroups and possession of ctx gene and then compared using two PCR based fingerprinting…
Platelet cut-off for anticoagulant therapy in thrombocytopenic patients with blood cancer and venous thromboembolism: an expert consensus
2019
Background. Management of venous thromboembolism (VTE) in patients with haematologic malignancies and thrombocytopenia is clinically challenging due to the related risks. No prospective studies or clinical trials have been carried out and, therefore, no solid evidence on this compelling issue is available. Methods. Given this, an expert panel endorsed by the Gruppo Italiano Malattie Ematologiche dell'Adulto Working Party on Thrombosis and Haemostasis was set up to produce a formal consensus, according to the RAND method, in order to issue clinical recommendations about the platelet (PLT) cut-off for safe administration of low molecular weight heparin (LMWH) in thrombocytopenic (PLT <100×…
Weighted and unweighted distances based decision tree for ranking data
2018
Preference data represent a particular type of ranking data (widely used in sports, web search, social sciences), where a group of people gives their preferences over a set of alternatives. Within this framework, distance-based decision trees represent a non-parametric tool for identifying the profiles of subjects giving a similar ranking. This paper aims at detecting, in the framework of (complete and incomplete) ranking data, the impact of the differently structured weighted distances for building decision trees. The traditional metrics between rankings don’t take into account the importance of swapping elements similar among them (element weights) or elements belonging to the top (or to …
Il "linguaggio" della Corte costituzionale: note sparse su alcuni aspetti dell'esperienza recente
2023
Wittgenstein's theories offer the starting point for looking at the socio-political implications of the language spoken by the institutions in the various historical phases: the communication system with which they relate to the outside world is functional in conveying the sense and scope of their action, building a precise relationship with public opinion. Starting from this assumption, the contribution takes into consideration some aspects of the recent practice of the Constitutional Court, with particular regard to press releases, and proposes an interpretation of the communication breakthrough pursued in recent years, relating it to the exercise of the function of warranty.