Search results for " Control"

showing 10 items of 7691 documents

Pharmacological interventions for somatoform disorders in adults

2014

BACKGROUND: Somatoform disorders are characterised by chronic, medically unexplained physical symptoms (MUPS). Although different medications are part of treatment routines for people with somatoform disorders in clinics and private practices, there exists no systematic review or meta-analysis on the efficacy and tolerability of these medications. We aimed to synthesise to improve optimal treatment decisions.OBJECTIVES: To assess the effects of pharmacological interventions for somatoform disorders (specifically somatisation disorder, undifferentiated somatoform disorder, somatoform autonomic dysfunction, and pain disorder) in adults.SEARCH METHODS: We searched the Cochrane Depression, Anxi…

Adultmedicine.medical_specialtylow-quality evidencemedicine.medical_treatmentPsychiatry and PsychologyAntidepressive Agents TricyclicCochrane LibraryPlaceboInternal medicineMedicine and Health SciencesmedicineHumansPharmacology (medical)somatoform disorderSomatoform DisordersAntipsychoticPsychiatryinterventionRandomized Controlled Trials as TopicPain disorderMedically unexplained physical symptomsbusiness.industrytrialsMiddle Agedmedicine.diseaseClinical trialPsychological Phenomena and ProcessesTolerabilityMeta-analysisAntidepressive Agents Second-GenerationbusinessSelective Serotonin Reuptake InhibitorsAntipsychotic AgentsCochrane Database of Systematic Reviews
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Uterine effects of clomiphene citrate in women with polycystic ovary syndrome: a prospective controlled study

2006

Background Previous data on the efficacy of clomiphene citrate, the most commonly used drug for treating anovulatory infertility in patients with polycystic ovary syndrome (PCOS), have shown a discrepancy between ovulation and pregnancy rates. In the present subanalysis (of a larger previously published randomized controlled trial), the effect of clomiphene citrate on several ultrasonographic markers of uterine receptivity in PCOS patients who ovulated under treatment was studied. Methods Thirty-three PCOS women who ovulated under 150 mg daily clomiphene citrate and 33 healthy controls were studied. Uterine, subendometrial and endometrial blood flows, endometrial thickness and pattern were …

Adultmedicine.medical_specialtymedia_common.quotation_subjectEarly Pregnancy LossUterusanovulation; clomiphene citrate; Doppler; PCOS; velocimetryBiologyClomiphenelaw.inventionAnovulationRandomized controlled trialPregnancyReference ValueslawClomifeneclomiphene citratemedicinePCOSHumansOvulationUltrasonographymedia_commonGynecologyPregnancyvelocimetryObstetricsRehabilitationEstrogen AntagonistsPregnancy OutcomeDopplerObstetrics and GynecologyGenitalia Femalemedicine.diseasePolycystic ovaryTreatment Outcomemedicine.anatomical_structureReproductive Medicinepolycystic ovary syndromeanovulationFemalemedicine.drug
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Low-molecular-weight heparin to prevent recurrent venous thromboembolism in pregnancy: Rationale and design of the Highlow study, a randomised trial …

2016

Summary Background Women with a history of venous thromboembolism (VTE) have a 2% to 10% absolute risk of VTE recurrence during subsequent pregnancies. Therefore, current guidelines recommend that all pregnant women with a history of VTE receive pharmacologic thromboprophylaxis. The optimal dose of low-molecular-weight heparin (LMWH) for thromboprophylaxis is unknown. In the Highlow study (NCT 01828697; www.highlowstudy.org ), we compare a fixed low dose of LMWH with an intermediate dose of LMWH for the prevention of pregnancy-associated recurrent VTE. We present the rationale and design features of this study. Methods The Highlow study is an investigator-initiated, multicentre, internation…

Adultmedicine.medical_specialtymedicine.drug_classPregnancy Complications CardiovascularLow molecular weight heparinHemorrhage030204 cardiovascular system & hematologylaw.inventionYoung Adult03 medical and health sciencesClinical trials0302 clinical medicineRandomized controlled trialRecurrencePregnancylawInternal medicineVenous thrombosisSecondary PreventionHumansMedicinecardiovascular diseasesPregnancy030219 obstetrics & reproductive medicineProphylaxisbusiness.industryPostpartum PeriodAbsolute risk reductionAnticoagulantsVenous ThromboembolismHematologyHeparinHeparin Low-Molecular-Weightmedicine.diseaseequipment and suppliesLMWHSurgeryClinical trialVenous thrombosisTreatment OutcomeGestationFemalebusinessmedicine.drug
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Different strategies for sports injury prevention in an America's Cup yachting crew.

2009

PURPOSE:: To analyze the effectiveness in reducing the number of sport injuries after application of different strategies of preventive physiotherapy during competition periods in an America's Cup yachting crew. METHODS:: A prospective physiotherapy intervention study during competition periods for three seasons was conducted on an America's Cup yachting race crew of 30 professional sailors. In the first two acts (2004), athletes did not receive any preventive physiotherapy. In the two acts celebrated in 2005, preventive intervention (phase 1) consisted of stretching exercises before the yacht race and preventative taping. During the four acts corresponding to the 2006 season, the physiothe…

Adultmedicine.medical_specialtymedicine.medical_treatmentCrewPoison controlPhysical Therapy Sports Therapy and RehabilitationAthletic PerformanceSuicide preventionCompetition (economics)Young AdultInjury preventionMedicineHumansOrthopedics and Sports MedicineProspective StudiesExercisePhysical Therapy ModalitiesShipsYachtingRehabilitationbiologybusiness.industryAthletesMiddle Agedbiology.organism_classificationAthletic InjuriesPhysical therapybusinessMedicine and science in sports and exercise
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Comparison of the effect of ginger and aloe vera mouthwashes on xerostomia in patients with type 2 diabetes: A clinical trial, triple-blind

2021

Background Ginger and aloe vera are two medicinal herbs mostly used to produce mouthwash. This study aimed to compare the effects of ginger and aloe vera mouthwashes on the xerostomia in patients referred to Bandar Abbas diabetes clinic (Iran). Material and Methods In this triple-blind clinical trial, three groups (n=35 patients in each group) were studied. One group was given aloe vera mouthwash, the other group used ginger mouthwash, and the control group was only given normal saline. All the mouthwashes were used 20 ccs three times daily for 14 consecutive days. The symptoms and severity of xerostomia were measured before and after the intervention by the questionnaire proposed by Fox et…

Adultmedicine.medical_specialtymedicine.medical_treatmentMouthwashesType 2 diabetesGingerIranXerostomiaAloe veralaw.inventionMcNemar's testbone regenerationstomatognathic systemRandomized controlled triallawInternal medicineDiabetes mellitusHumansMedicineIn patientthird molarxenograftAloeGeneral DentistrySalineUNESCO:CIENCIAS MÉDICASAgedtooth extractionOral Medicine and Pathologybiologybusiness.industryResearchMiddle Agedbiology.organism_classificationmedicine.diseaseClinical trialDiabetes Mellitus Type 2OtorhinolaryngologySurgerybusinessMedicina Oral Patología Oral y Cirugia Bucal
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How Technology Can Impact Surgeon Performance: A Randomized Trial Comparing 3-Dimensional versus 2-Dimensional Laparoscopy in Gynecology Oncology

2016

This randomized clinical trial (Canadian Task Force classification I) aimed to compare 2-dimension (2-D) versus 3-dimensional (3-D) laparoscopic hysterectomy and pelvic lymphadenectomy in endometrial and cervical cancer patients. Between December 2014 and March 2015, 90 patients were enrolled: 29 (32.2%) with early or locally advanced cervical cancer after neoadjuvant treatment and 61 (67.8%) with early-stage endometrial cancer. Patients were randomly assigned to undergo 2-D (Group A, n = 48 [53.3%]) or 3-D (Group B, n = 42 [46.7%)]) laparoscopy. Baseline characteristics were superimposable in the 2 groups. Median operative time was similar in the 2 groups. Median estimated blood loss durin…

Adultmedicine.medical_specialtymedicine.medical_treatmentOperative TimeUterine Cervical NeoplasmsHysterectomylaw.invention03 medical and health sciencesImaging Three-DimensionalPostoperative Complications0302 clinical medicineRandomized controlled trialEndometrial cancerlawThree-dimensional laparoscopicmedicineHumansLaparoscopyNeoadjuvant therapyCervical cancer; Endometrial cancer; Three-dimensional laparoscopicAgedSurgeonsGynecologyCervical cancerHysterectomymedicine.diagnostic_testbusiness.industryEndometrial cancerGeneral surgeryObstetrics and GynecologyPerioperativeMiddle Agedmedicine.diseaseNeoadjuvant TherapyEndometrial NeoplasmsSurgery030220 oncology & carcinogenesisCervical cancerLymph Node ExcisionFemaleLaparoscopy030211 gastroenterology & hepatologyLymphadenectomyClinical CompetenceCervical cancer; Endometrial cancer; Three-dimensional laparoscopic; Obstetrics and Gynecologybusiness
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Prospective randomized comparison of conventional instruments and the Harmonic Focus(®) device in breast-conserving therapy for primary breast cancer.

2011

Abstract Background In recent years, surgeons have utilized Harmonic instruments to perform breast cancer resection. Retrospective and prospective studies have demonstrated that the use of this surgical device for mastectomy and axillary dissection can reduce perioperative blood loss, seroma formation, and duration and total amount of drainage. No study has analyzed the feasibility of Harmonic instruments in breast-conserving surgery. We conducted a prospective, randomized clinical trial comparing Harmonic instrument and conventional surgery in the performance of breast-conserving surgery and axillary procedures to determine differences in surgical procedures, postoperative outcome, and com…

Adultmedicine.medical_specialtymedicine.medical_treatmentUltrasonic TherapyBreast NeoplasmsMastectomy SegmentalRisk AssessmentStatistics Nonparametriclaw.inventionBreast cancerPostoperative ComplicationsRandomized controlled triallawGermanymedicineBreast-conserving surgeryHumansNeoplasm InvasivenessProspective StudiesProspective cohort studyAgedNeoplasm StagingPostoperative CareAcademic Medical CentersChi-Square Distributionbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseSurgical InstrumentsSurvival AnalysisSurgeryLogistic ModelsSeromaTreatment OutcomeOncologySeromaMultivariate AnalysisSurgeryFemaleNeoplasm Recurrence LocalComplicationbusinessChi-squared distributionMastectomyFollow-Up StudiesEuropean journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
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Does the use of fibrin glue prevent seroma formation after axillary lymphadenectomy for breast cancer? A prospective randomized trial in 159 patients.

2010

Background Seroma formation frequently occurs in patients who have undergone axillary lymphadenectomy. The aim of the study was to evaluate the effect of fibrin glue in the prevention of seroma formation after axillary lymphadenectomy. Materials and Methods Hundred fifty-nine breast cancer patients about to undergo quadrantectomy or mastectomy plus axillary lymphadenectomy were enrolled in the study and randomized into two groups. Fibrin glue spray applied to the axillary fossa plus placement of closed suction drainage were used in 80 patients (group A); placement of closed suction drainage was only used in 79 patients (group B). Results Group A patients showed a slight advantage with regar…

Adultmedicine.medical_specialtymedicine.medical_treatmentseroma formationBreast NeoplasmsFibrin Tissue AdhesiveSuctionlaw.inventionbreast cancerBreast cancerPostoperative ComplicationsRandomized controlled triallawmedicineHumansIn patientProspective StudiesFibrin glueMastectomyAgedAged 80 and overbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseSurgeryfibrin glueSettore MED/18 - Chirurgia Generalesurgical procedures operativeSeromaOncologyAxillary LymphadenectomySeromaAxillaLymph Node ExcisionSurgeryFemaleTissue Adhesivesaxillary lymphadenectomybusinessQuadrantectomyMastectomyJournal of surgical oncology
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Validity and Reliability of the Spanish Version of the "Abuse Assessment Screen" among Pregnant Women.

2016

Objective: To assess the reliability, accuracy, and construct validity of the Spanish Abuse Assessment Screen (AAS) among pregnant women using the Spanish version of Index of Spouse Abuse (ISA) as a reference standard. Design and Sample: Cross-sectional survey. A total of 1,329 pregnant women were selected in nine primary care centers during 2008-2009. Measures: The Spanish ISA was self-administered first, followed by the AAS, administered by the midwife. Sensitivity, specificity, and predictive values of the Spanish AAS were compared with the Spanish version of the ISA as a reference standard. Results: Percentage of agreement between initial and retest administration of the Spanish AAS was…

Adultmedicine.medical_specialtyvalidityPsychometricsintimate partner violenceValidityPoison control03 medical and health sciences0302 clinical medicinePregnancySurveys and QuestionnairesInjury preventionMedicineHumans030212 general & internal medicinePsychiatryPsychological abusereproducibilityGeneral Nursing030219 obstetrics & reproductive medicinebusiness.industryscreeningPublic Health Environmental and Occupational HealthConstruct validityReproducibility of ResultsTranslatingPhysical abuseCross-Sectional StudiesSpouseSpainSpouse AbuseDomestic violenceFemalepregnancyPregnant WomenbusinessPublic health nursing (Boston, Mass.)
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Long-term use of high-heeled shoes alters the neuromechanics of human walking

2012

Human movement requires an ongoing, finely tuned interaction between muscular and tendinous tissues, so changes in the properties of either tissue could have important functional consequences. One condition that alters the functional demands placed on lower limb muscle-tendon units is the use of high-heeled shoes (HH), which force the foot into a plantarflexed position. Long-term HH use has been found to shorten medial gastrocnemius muscle fascicles and increase Achilles tendon stiffness, but the consequences of these changes for locomotor muscle-tendon function are unknown. This study examined the effects of habitual HH use on the neuromechanical behavior of triceps surae muscles during w…

Adultmusculoskeletal diseasesMuscle fasciclemedicine.medical_specialtyHeelKnee JointPhysiologyPoison controlStrain (injury)WalkingAchilles TendonPhysiology (medical)HumansMedicineGround reaction forceMuscle SkeletalGaitAchilles tendonMuscle fatigueElectromyographyFootbusiness.industrymedicine.diseaseGaitBiomechanical PhenomenaShoesmedicine.anatomical_structurePhysical therapyFemaleHeelbusinessAnkle JointJournal of Applied Physiology
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