Search results for " Coronaviru"
showing 10 items of 730 documents
Delaying surgery for patients with a previous SARS-CoV-2 infection
2020
With at least 28 elective million operations delayed during the first three months of the COVID-19 pandemic, the number of patients who will require surgery after a previous SARS-CoV-2 infection is likely to increase rapidly1. Operating on patients with an active perioperative SARS-CoV-2 infection is now known to carry a very high pulmonary complication and mortality rate2. Urgent information is needed to guide whether postponing surgery in patients with a previous SARS-CoV-2 infection leads to a clinical benefit, and the optimal length of delay.
Fear of Coronavirus, Stress and Fear of Childbirth in Polish Pregnant Women during the COVID-19 Pandemic
2021
The COVID-19 pandemic is the largest pandemic of an aggressive coronavirus in the human population in the 21st century. The pandemic may have a negative emotional impact on pregnant women, causing fear and stress. Negative feelings during pregnancy later affect fear of childbirth. Our study aimed to determine the relationship between fear of COVID-19, stress and fear of childbirth. We assume that fear of COVID-19 will be a mediator of the relationship between perceived stress and fear of childbirth. A total of 262 Polish pregnant women participated in this study. Perceived Stress Scale (PSS-10), Fear of COVID-19 Scale (FOC-6) and Labour Anxiety Questionnaire (KLP II) were used in the study.…
SARS-CoV-2 Antibody Screening in Healthcare Workers in Non-Infectious Hospitals in Two Different Regions of Southern Poland (Upper Silesia and Opole …
2021
(1) Background: Detection of asymptomatic or subclinical human coronavirus SARS-CoV-2 infection in healthcare workers (HCWs) is crucial for understanding the overall prevalence of the new coronavirus and its infection potential in public (non-infectious) healthcare units with emergency wards. (2) Methods: We evaluated the host serologic responses, measured with semi-quantitative ELISA tests (IgA, IgG, IgM abs) in sera of 90 individuals in Hospital no. 4 in Bytom, 84 HCWs in the University Hospital in Opole and 25 in a Miasteczko Śląskie local surgery. All volunteers had negative RT-PCR test results or had not had the RT-PCR test performed within 30 days before sampling. The ELISA test was m…
COVID-19, 'FAKE NEWS' Y VACUNACIÓN: LA NECESIDAD DE INMUNIZAR A LA SOCIEDAD DE LA DUDA VACUNAL
2021
One of the keys to overcoming the COVID-19 pandemic is the development of the vaccine in order to immunize the population. In addition to the medical complications to obtain the vaccine, we highlight the presence of other problems, such as the dissemination of fake news that add difficulties to overcoming the global problem, especially due to its incidence in the field of anti-vaccine movements, which have developed, with special presence in Italy in recent years. For this, we warn of the need to be prepared to overcome the two pandemics that are developing in parallel, the one caused by the virus and the one generated by the fake news.
Migrations, Populisms and Emergencies: A Sicilian Case Study
2022
The contemporary political situation has been characterized, in recent years, by the emergence of multiple forms of populism. Since populist discourses have often used migrants and migrations instrumentally, one should clarify what populism, souverainism and the ‘spatialization of fear’ actually mean. In this sense, many European states have ambiguously wavered between the rejection of supranational entities (as in the case of the United Kingdom with the Brexit, or the first version of Marine Le Pen’s Front National) and the desire to strengthen European borders, considered culturally homogeneous, against the ‘threat’ of foreigners arriving from Africa and Asia. Ever since the coronavirus e…
The relationship between fear of COVID-19 and intention to get vaccinated. The serial mediation roles of existential anxiety and conspiracy beliefs
2021
Abstract Today, we witness the progress toward global COVID-19 vaccinations organized by countries worldwide. Experts say a mass vaccination plan is the only effective antidote against the spread of SARS-COV-2. However, a part of the world population refuses vaccination. The present study aimed to understand the impact of some individual variables on the intention to get vaccinated. Through a serial mediation model, we tested the influence of fear of COVID-19 on the intention to get vaccinated and the serial mediating effect of existential anxiety and conspiracy beliefs. Via a cross-sectional design this research was conducted with the participation of 223 French adults (Female: 69.5%; Male…
Differing kinetics of anti-spike protein IgGs and neutralizing antibodies against SARS-CoV-2 after Comirnaty (BNT162b2) immunization
2022
Abstract Aims Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection has had a serious worldwide impact on human health. On December 2020, an immunization campaign with a COVID-19 mRNA vaccine (Comirnaty-BNT162b2 Pfizer-BioNTech) was started in Italy, first targeting healthcare workers (HCWs). This study aims to investigate the antibodies that are response against SARS-CoV-2 vaccine. Methods and Results The kinetics and the persistence of both anti-S1/S2 IgGs and neutralizing antibodies (Nt-Abs) were investigated in 76 HCWs through a 4-month follow-up with multiple testing points starting at the first dose. Temporal analysis of SARS-CoV-2 Abs titre kinetics showed three diff…
Diffusion modeling of COVID-19 under lockdown
2021
Viral immune evasion by sequence variation is a significant barrier to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine design and coronavirus disease-2019 diffusion under lockdown are unpredictable with subsequent waves. Our group has developed a computational model rooted in physics to address this challenge, aiming to predict the fitness landscape of SARS-CoV-2 diffusion using a variant of the bidimensional Ising model (2DIMV) connected seasonally. The 2DIMV works in a closed system composed of limited interaction subjects and conditioned by only temperature changes. Markov chain Monte Carlo method shows that an increase in temperature implicates reduced virus diffusi…
Suitability of two rapid lateral flow immunochromatographic assays for predicting SARS‐CoV‐2 neutralizing activity of sera
2020
Purpose: Assessment of commercial SARS-CoV-2 immunoassays for their capacity to provide reliable information on sera neutralizing activity is an emerging need. We evaluated the performance of two commercially-available lateral flow immunochromatographic assays (LFIC) (Wondfo SARS-CoV-2 Antibody test and the INNOVITA 2019-nCoV Ab test) in comparison with a SARS-CoV-2 neutralization pseudotyped assay for COVID-19 diagnosis in hospitalized patients, and investigate whether the intensity of the test band in LFIC associates with neutralizing antibody (NtAb) titers. Patients and Methods: Ninety sera were included from 51 patients with moderate to severe COVID-19. A green fluorescent protein (GFP)…
Does SARS-CoV-2 Trigger Stress-InducedAutoimmunity by Molecular Mimicry? A Hypothesis.
2020
Viruses can generate molecular mimicry phenomena within their hosts. Why shouldsevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) not be considered one of these?Information in this short review suggests that it might be so and, thus, encourages research aimingat testing this possibility. We propose, as a working hypothesis, that the virus induces antibodiesand that some of them crossreact with host’s antigens, thus eliciting autoimmune phenomena withdevasting consequences in various tissues and organs. If confirmed, by in vitro and in vivo tests,this could drive researchers to find effective treatments against the virus.