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showing 10 items of 519 documents

Development of artemisinin resistance in malaria therapy

2019

Malaria affects 200 million people worldwide. Today, the most successful treatments are artemisinin-based combination therapies (ACT). Resistance has already been described for the elder anti-malarials chloroquine, sulfadoxine-pyrimethamine and mefloquine. Unfortunately, over the last few years there has also been an emerging resistance to the successfully used drug artemisinin, especially in African and Asian countries. A systematic PubMed literature research was conducted for studies published between January 2002 and December 2018. Despite ACTs continue to be first line treatment, the number of studies is rising reporting on artemisinin resistance mutations. Most publications reported on…

0301 basic medicinemedicine.medical_specialtyDrug ResistanceAntimalarials03 medical and health sciences0302 clinical medicineChloroquineparasitic diseasesAsian countryAnimalsHumansMedicineArtemisininIntensive care medicinePharmacologyPolymorphism Geneticbusiness.industryMefloquineArtemisinin resistancemedicine.diseaseArtemisininsTreatment efficacyMalariaFirst line treatment030104 developmental biology030220 oncology & carcinogenesisMutationbusinessMalariamedicine.drugPharmacological Research
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Pan-Asian adapted ESMO Clinical Practice Guidelines for the management of patients with intermediate and advanced/relapsed hepatocellular carcinoma: …

2020

The most recent version of the European Society for Medical Oncology (ESMO) Clinical Practice Guidelines for the diagnosis, treatment and follow-up of hepatocellular carcinoma (HCC) was published in 2018, and covered the diagnosis, management, treatment and follow-up of early, intermediate and advanced disease. At the ESMO Asia Meeting in November 2018 it was decided by both the ESMO and the Taiwan Oncology Society (TOS) to convene a special guidelines meeting immediately after the Taiwan Joint Cancer Conference (TJCC) in May 2019 in Taipei. The aim was to adapt the ESMO 2018 guidelines to take into account both the ethnic and the geographic differences in practice associated with the treat…

0301 basic medicinemedicine.medical_specialtyESMO guidelinesDrug availability03 medical and health sciences0302 clinical medicineAdvanced diseaseAsian countryconsensuMedicineHCCReimbursementESMO guidelinePan-Asianbusiness.industryCancer conferenceRelapsed Hepatocellular CarcinomaHematologyhepatocellular carcinomaClinical Practice030104 developmental biologyOncologyconsensus030220 oncology & carcinogenesisFamily medicinebusiness
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Motivations for Business Start-up: Are There any Differences Between Disabled and Non-disabled Microfinance Clients?

2015

We use an Ecuadorian sample to investigate if there are differences in motivations for business start-up between persons with and without disabilities. Generally, we do not document significant differences. The reason might be that we use a sample selected among customers of the microfinance bank Banco D-MIRO. Without targeted incentives, disabled microfinance customers must resemble non-disabled customers. Copyright © 2015 John Wiley & Sons, Ltd.

030506 rehabilitationEconomic growthEntrepreneurshipMicrofinance05 social sciencesGeography Planning and DevelopmentDeveloping countrySample (statistics)DevelopmentStart uplaw.inventionPeer review03 medical and health sciencesIncentivelaw0502 economics and businessEconomicsMarketing0305 other medical science050203 business & managementJournal of International Development
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Balance Perturbations as a Measurement Tool for Trunk Impairment in Cross-Country Sit Skiing

2018

In cross-country sit-skiing, the trunk plays a crucial role in propulsion generation and balance maintenance. Trunk stability is evaluated by automatic responses to unpredictable perturbations; however, electromyography is challenging. The aim of this study was to identify a measure to group sit-skiers according to their ability to control the trunk. Seated in their competitive sit-ski, 10 male and 5 female Paralympic sit-skiers received 6 forward and 6 backward unpredictable perturbations in random order. k-means clustered trunk position at rest, delay to invert the trunk motion, and trunk range of motion significantly into 2 groups. In conclusion, unpredictable perturbations might quantif…

030506 rehabilitationmedicine.medical_specialtyComputer sciencek-meanstasapainoPhysical Therapy Sports Therapy and RehabilitationElectromyographyRandom order03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationcore stabilitymedicineParalympicsBalance (ability)selkäydinvammatparalympialaisetCross countryParalympics spinal cord injurymedicine.diagnostic_testCore stability030229 sport scienceshiihtoautomatic responses core stability k-means Paralympics spinal cord injuryTrunkspinal cord injuryautomatic responses0305 other medical scienceRange of motionhuman activities
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Do Large European Banks Differ in their Derivative Disclosure Practices? A Cross-country Empirical Study.

2019

Risk disclosure has strategic importance for the efficiency of financial markets and overall financial stability. It plays a pivotal role in strengthening market discipline and building trust to improve relationships with stakeholders in banking. Risk reporting has taken a growing importance in banking over the last years. The topic of this paper is derivative reporting in banking. The authors employ content analysis to conduct an empirical study on a sample of large European banks. The authors propose a hybrid scoring model for the assessment of derivative disclosure in banking institutions. The methodology employed in this research is able to capture a considerable amount of information b…

050208 financeCross countryderivatives risk reporting risk disclosure banking risk management financial regulation.Settore SECS-P/11 - Economia Degli Intermediari Finanziari05 social sciencesSample (statistics)050201 accountingQualitative analysisEmpirical researchDerivative (finance)Content analysisAccounting0502 economics and businessEconometricsBusinessGeneral Economics Econometrics and Finance
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ICT Barriers and Critical Success Factors in Developing Countries

2013

Since the early 1990s, Information and Communication Technology (ICT) has been perceived as a catalyst for development. However, the UNICEF State of the World’s Children Report 2011 acknowledges that the poor in many developing countries remain largely excluded from ICT and its benefits. This paper aims to address three issues. Firstly, identify ICT barriers in the literature from 2000 to 2011. Secondly, identify ICT barriers through empirical findings and thirdly, categorize these barriers into critical success factors. These aims are achieved by comparing the findings in the literature to our recent empirical results. Two methodologies are used in this study, namely, a systematic literatu…

050208 financebusiness.industry05 social sciencesDeveloping countryInternet exchange pointPublic relationsSystematic reviewCategorizationRankingInformation and Communications TechnologyPolitical science0502 economics and businessCritical success factor050207 economicsbusinessCitationInformation SystemsThe Electronic Journal of Information Systems in Developing Countries
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Methodology and trends for an intelligent transport system in developing countries

2018

Abstract Increasingly, the technologies that are used in telecommunications contribute to improve intelligent transport systems. These technologies are systems that offer several concepts like vehicular ad hoc networks, which allow reduction of traffic accidents, traffic congestion and consequently increase road safety and the comfort of road users. Developing countries in general and those of sub-Sahara in particular do not have telecommunication infrastructures, even road infrastructures for the implementation of an intelligent transport system. Moreover, with the serious increase in vehicles in these countries, the problem of traffic regulation arise especially in the inter-urban context…

050210 logistics & transportationGeneral Computer ScienceWireless ad hoc networkComputer science05 social sciencesTransport network1. No povertyDeveloping country020206 networking & telecommunicationsContext (language use)02 engineering and technology[INFO.INFO-AI]Computer Science [cs]/Artificial Intelligence [cs.AI][INFO.INFO-NI]Computer Science [cs]/Networking and Internet Architecture [cs.NI]Risk analysis (engineering)Traffic congestion11. Sustainability0502 economics and business0202 electrical engineering electronic engineering information engineeringIntelligent transportElectrical and Electronic EngineeringIntelligent transportation systemComputingMilieux_MISCELLANEOUSRoad user
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Competition and cooperation for intermodal container transhipment: A network optimization approach

2018

Abstract This study presents an analysis of cross-border competition and cooperation between ports in Bangladesh and India. Nepal and Bhutan are countries without access to seaports — two landlocked countries in South Asia, depending solely on the Indian port of Kolkata for their international seaborne trade. Alternatives do exist in the Bangladeshi ports of Chittagong and Mongla but these are not exploited, in spite of trade agreements that allow access to a third country's port, and/or crossing the land of a third, intermediate, country. We formulate a mixed integer linear programming optimization model to find the optimum economic benefit of port users (serving Bhutan, Nepal and Northeas…

050210 logistics & transportationSouth asiaStrategy and Management05 social sciencesEconomics Econometrics and Finance (miscellaneous)General Decision SciencesTransportation010501 environmental sciencesManagement Science and Operations Research01 natural sciencesPort (computer networking)Competition (economics)Tourism Leisure and Hospitality Management0502 economics and businessContainer (abstract data type)BusinessBusiness and International ManagementLandlocked countryRobustness (economics)Integer programmingSensitivity analysesIndustrial organization0105 earth and related environmental sciencesResearch in Transportation Business & Management
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Russian-Speaking Immigrant Teachers in Finnish Classrooms: <i>Views and lived experiences in Finnish education</i>

2017

Success of integration depends, amongst other things, on immigrants’ involvement in the host country’s education. Educational differences between home and host countries can either promote or hinder academic progress of immigrants and, consequently, overall process of their integration. The goal of this study is to investigate what effect differences between educational systems of Finland and neighbouring Russia may have on professional induction of Russian-speaking immigrant teachers in Finland. This is done through researching experiences of Russian-speaking teachers in Finnish education. Their views and interpretations of their own eligibility and Finnish schooling practices lay foundati…

060201 languages & linguisticsmedia_common.quotation_subjectLived experience05 social sciencesImmigration050301 education06 humanities and the artsHost country0602 languages and literaturePedagogySociology0503 educationEducational systemsmedia_commonNordic Journal of Migration Research
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La patria potestad prorrogada y la patria potestad rehabilitada en el nuevo proyecto de ley de reforma de la legislación civil y procesal para el apo…

2021

It is intended to analyze and reflect in the present work about the institution of the extension of parental authority and parental authority rehabilitated in the new regulation in the Draft Law that reforms the civil and procedural legislation to support people with disabilities in the exercise of their legal capacity. In this project, the extended parental authority and the rehabilitated parental authority are eliminated from the scope of disability, following a criterion that demands the treatment of people with disabilities with the attention that their specific situation requires, eliminating a regime that seems contrary to the system of promoting the autonomy of adults with disabiliti…

:CIENCIAS JURÍDICAS [UNESCO]parental authorityrehabilitacióneliminating a regime that seems contrary to the system of promoting the autonomy of adults with disabilities. This study is linked and addressedas they will be affected by the reform and by the effect of the structural deficiencies suffered by the Justice system of our country. the present work about the institution of the extension of parental authority and parental authority rehabilitated in the new regulation in the Bill of Law that reforms the civil and procedural legislation to support people with disabilities in the exercise of its legal capacity. In this projectelimination 236 251eliminaciónrehabilitationPablo It is intended to analyze and reflect in the present work about the institution of the extension of parental authority and parental authority rehabilitated in the new regulation in the Draft Law that reforms the civil and procedural legislation to support people with disabilities in the exercise of their legal capacity. In this projectprojectproyectoUNESCO::CIENCIAS JURÍDICASthe extended parental authority and the rehabilitated parental authority are eliminated from the scope of disabilitypatria potestadExtensionwith the characteristics and needs of people with a severe intellectual disabilityas they will be affected by the reform and by the effect of the structural insufficiencies suffered by the Justice system of our country. Prórroga2070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055222 La patria potestad prorrogada y la patria potestad rehabilitada en el nuevo proyecto de ley de reforma de la legislación civil y procesal para el apoyo a las personas con discapacidad (actual ley 8/2021) Tortajada Chardífollowing a criterion that demands the treatment of people with disabilities with the attention that their specific situation requireshealth care economics and organizations
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