Search results for " Covid"
showing 10 items of 513 documents
Vivere come donne in India: l'insolito genere delle comunità hijra
2021
The study aims to investigate the history and practices that characterize hijra communities in India in order to shed light on the specific reality of these heterogeneous communities of individuals who are placed outside the heteronormative identity codes, but who have historically been included within Indian society, with very specific roles, thanks to the elaboration of the notion of tṛtīya prakṛti (third gender). However, historical events, especially since the British colonial period, have made the position of hijras increasingly marginal: the various forms of discrimination and violence, which take place within the family of origin, the health system, and society in general, were furth…
Circulating histones contribute to monocyte and MDW alterations as common mediators in classical and COVID-19 sepsis
2022
Abstract Objective Histone proteins are physiologically involved in DNA packaging and gene regulation but are extracellularly released by neutrophil/monocyte extracellular traps and mediate thrombo-inflammatory pathways, associated to the severity of many human pathologies, including bacterial/fungal sepsis and COVID-19. Prominent and promising laboratory features in classic and viral sepsis emphasize monocyte distribution width (MDW), due to its ability to distinguish and stratify patients at higher risk of critical conditions or death. No data are available on the roles of histones as MDW modifiers. Design Comparison of MDW index was undertaken by routine hematology analyzer on whole bloo…
#IoRestosenzaCasa. La condizione delle persone senza dimora durante la pandemia
2020
To reach the identification of the serious marginality, in a moment of pandemic, is not a very simple operation considering the amplification of inequalities throughout the national territory, but also internationally. The Covid-19 pandemic has severely tested the resilience of States and social and health care systems. It is inevitable that the most affected by the lockdown, which marked the country from March to May 2020, were the homeless. When we talk about homeless people, issues, questions, difficulties arise immediately. The first limit is to have the count of the phenomenon in numerical terms. Data on the presence of homeless people in Italy date back to 2014 and estimate 50,724 hom…
Update I. A systematic review on the efficacy and safety of chloroquine/hydroxychloroquine for COVID-19
2020
Purpose To assess efficacy and safety of chloroquine (CQ)/hydroxychloroquine (HCQ) for treatment or prophylaxis of COVID-19 in adult humans. Materials and methods MEDLINE, PubMed, EMBASE and two pre-print repositories (bioRxiv, medRxiv) were searched from inception to 8th June 2020 for RCTs and nonrandomized studies (retrospective and prospective, including single-arm, studies) addressing the use of CQ/HCQ in any dose or combination for COVID-19. Results Thirty-two studies were included (6 RCTs, 26 nonrandomized, 29,192 participants). Two RCTs had high risk, two ‘some concerns’ and two low risk of bias (Rob2). Among nonrandomized studies with comparators, nine had high risk and five moderat…
National identity predicts public health support during a global pandemic
2022
Funder: Research Council of Norway through its Centres of Excellence Scheme, FAIR project No 262675
The impact of the coronavirus crisis on European societies. What have we learnt and where do we go from here? – Introduction to the COVID volume
2021
The coronavirus pandemic, which first impacted European societies in early 2020, has created a twofold crisis by combining a health threat with economic turmoil. While the crisis has affected all European societies very significantly, its impact varies across countries, social groups, and societal domains. In an effort to provide a first overview of the effect of the coronavirus crisis, in this editorial we discuss contributions of 58 papers published as part of this special issue. These early research papers illustrate the varied impact of the pandemic on various areas of social life. The first group of studies in this special issue analyzes the effect of the pandemic on social inequalitie…
Clinical Severity in Different Waves of SARS-CoV-2 Infection in Sicily: A Model of Smith’s “Law of Declining Virulence” from Real-World Data
2022
Background: The COVID-19 epidemic had a rapid spread worldwide with a continuous and fast mutation of the virus, resulting in the emergence of several variants of concern (VOC). The aim of this study was to evaluate the severity of each VOC among SARS-CoV-2 infected subjects by investigating deaths, ICU admissions, intubations, and severe critical symptoms. Methods: An ecological observational study was performed to evaluate mortality rates and clinical characteristics of 321,490 unvaccinated Sicilian SARS-CoV-2 cases observed from 2 March 2020 to 27 March 2022. Odds ratios (OR) and 95% confidence intervals (CI) were calculated by multivariate logistic regression analysis evaluating factors…
Acute Stroke Care during COVID-19: National Data.
2022
(1) Background: The pandemic of COVID-19 and subsequent lockdown strategies had a profound impact on many aspects of everyday life. During this time the world faced the unprecedented crisis of healthcare disrupting timely care delivery. This study was designed to evaluate the impact of the pandemic on the acute treatment of stroke in Poland. (2) Methods: The national data on hospitalizations with stroke as a primary diagnosis were obtained from the National Health Fund of Poland. Poisson regression was used to determine the significance of the change in hospital admissions. The differences between proportions were analyzed using the “N-1” Chi-squared test. (3) Results: During the COVID-19 p…
Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020
2020
8 páginas, 3 figuras
Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021
2021
COVID study groups - PORTUGAL: Portuguese Laboratory Network for the Diagnosis of COVID-19 and Public Health Department of the Health Administrative Regions, Physicians that provided data and samples from suspected cases and SARS-CoV-2 genetic characterization. INSA laboratory team for the diagnosis of SARS-CoV-2. Algarve Biomedical Center and Unilabs. We compared 19,207 cases of SARS-CoV-2 variant B.1.1.7/S gene target failure (SGTF), 436 B.1.351 and 352 P.1 to non-variant cases reported by seven European countries. COVID-19 cases with these variants had significantly higher adjusted odds ratios for hospitalisation (B.1.1.7/SGTF: 1.7, 95% confidence interval (CI): 1.0-2.9; B.1.351: 3.6, 95…