Search results for " Cyclic"
showing 3 items of 163 documents
Parameterizing 'lexical subject-finite verb' inversion across Verb Second languages: On the role of Relativized Minimality at the vP edge
2020
By discussing novel data from two Dolomitic Ladin languages spoken in Northern Italy, Badiotto and Gardenese, we show that in these Verb-second languages subject-finite verb inversion i) is constrained by the syntactic (adverb or object) and discourse (focus or topic) nature of the sentence-initial constituent, and by the discourse status of the DP subject. We demonstrate that in both varieties subjects in inversion either appear in a FocusP of the vP periphery (Belletti 2004, Poletto 2010) or in an A position in the IP layer, and that the observed distribution of inversion follows from two universal constraints of movement affecting extraction through the vP edge: a) cyclicity (extraction …
Tumor targeting of baculovirus displaying a lymphatic homing peptide.
2008
Background Tumor-associated cells and vasculature express attractive molecular markers for site-specific vector targeting. To attain tumor-selective tropism, we recently developed a baculovirus vector displaying the lymphatic homing peptide LyP-1, originally identified by ex vivo/in vivo screening of phage display libraries, on the viral envelope by fusion to the transmembrane anchor of vesicular stomatitis virus G-protein. Methods In the present study, we explored the specificity and kinetics of viral binding and internalization as well as in vivo tumor homing of the LyP-1 displaying virus to elucidate the applicability of baculovirus for targeted therapies. Results We demonstrated that th…
Three existence theorems for weak contractions of Matkowski type
2010
We prove three generalizations of Matkowski’s fixed point theorems for weakly contractions.