Search results for " DAP."

showing 10 items of 22 documents

Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-…

2017

Background Dapagliflozin is a sodium-glucose cotransporter-2 inhibitor approved for the treatment of type 2 diabetes. We aimed to assess the efficacy and safety of dapagliflozin as an add-on to adjustable insulin in patients with inadequately controlled type 1 diabetes. Methods DEPICT-1 was a double-blind, randomised, parallel-controlled, three-arm, phase 3, multicentre study done at 143 sites in 17 countries. Eligible patients were aged 18–75 years and had inadequately controlled type 1 diabetes (HbA1c between ≥7·7% and ≤11·0% [≥61·0 mmol/mol and ≤97·0 mmol/mol]) and had been prescribed insulin for at least 12 months before enrolment. After an 8 week lead-in period to optimise diabetes man…

MaleGlycated Hemoglobin AEndocrinology Diabetes and MetabolismType 2 diabetes030204 cardiovascular system & hematologySettore MED/13 - Endocrinologialaw.inventionchemistry.chemical_compound0302 clinical medicineEndocrinologydiabetes dapaglifozinGlucosidesRandomized controlled triallawInsulin03.02. Klinikai orvostanDapagliflozinMiddle AgedDiabetes and MetabolismTreatment OutcomeCombinationDrug Therapy CombinationFemaleType 1Adultmedicine.medical_specialtyDiabetic ketoacidosis030209 endocrinology & metabolismPlacebo03 medical and health sciencesDrug TherapyDiabetes managementDiabetes mellitusInternal medicineDiabetes MellitusInternal MedicinemedicineHumansHypoglycemic AgentsBenzhydryl CompoundsAdult; Benzhydryl Compounds; Body Weight; Diabetes Mellitus Type 1; Drug Therapy Combination; Female; Glucosides; Glycated Hemoglobin A; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Treatment OutcomeAdult; Benzhydryl Compounds; Body Weight; Diabetes Mellitus Type 1; Drug Therapy Combination; Female; Glucosides; Glycated Hemoglobin A; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Middle Aged; Treatment Outcome; Internal Medicine; Endocrinology Diabetes and Metabolism; EndocrinologyGlycated HemoglobinType 1 diabetesbusiness.industryBody Weightmedicine.diseaseHypoglycemiaSurgeryDiabetes Mellitus Type 1chemistrybusinessThe Lancet Diabetes & Endocrinology
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Daptomycin non-susceptible, vancomycin intermediate methicillin-resistant Staphylococcus aureus ST398 from a chronic leg ulcer, Italy

2010

To the Editor,Human infections caused by methicillin-resistant Staphylococcus aureus (MRSA) sequence type 398 (ST398) have been emerging in recent y in Europe [1–3]. Most studies have shown a stron...

Microbiology (medical)Settore MED/07 - Microbiologia E Microbiologia ClinicaMicrococcaceaeGeneral Immunology and Microbiologybiologymedicine.drug_classbusiness.industryAntibioticsGeneral Medicinebiochemical phenomena metabolism and nutritionbacterial infections and mycosesmedicine.disease_causebiology.organism_classificationMethicillin-resistant Staphylococcus aureusMicrobiologyInfectious DiseasesStaphylococcus aureusmedicineMRSA daptomycin drug resistanceVancomycinDaptomycinbusinessmedicine.drugAntibacterial agentStaphylococcal Skin InfectionsScandinavian Journal of Infectious Diseases
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Systemic lupus erythematosus and bullous pemphigoid with dramatic response to dapsone

2017

Patient: Female, 11 Final Diagnosis: Bullous pemphigoid in systemic lupus erythematosus Symptoms: Bullous lupus • photosensitive rash • synovitis Medication:— Clinical Procedure: Pharmacological treatment Specialty: Rheumatology Objective: Unusual clinical course Background: Bullous pemphigoid is an autoimmune blistering disease, with relapses, isolated or associated with other autoimmune diseases such as systemic lupus erythematosus (SLE). Joint manifestations rapidly respond to small or moderate doses of corticosteroids, whereas skin manifestations usually respond to antimalarial drugs. Case Report: We describe the clinical case of an 11-year-old girl with SLE. She showed bullous skin les…

Pemphigoidmedicine.medical_specialtyAntimalarials; Child; Dapsone; Female; Humans; Lupus Erythematosus Systemic; Pemphigoid BullousMild proteinuriaArthritisDapsoneAntimalarials030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineSettore MED/38 - Pediatria Generale E SpecialisticaPrednisoneimmune system diseasesPemphigoid BullousmedicineHumansChildskin and connective tissue diseases030203 arthritis & rheumatologyLupus erythematosusintegumentary systembusiness.industryMedicine (all)Dapsone; Lupus erythematosus systemic; Pemphigoid bullous; Medicine (all)ArticlesGeneral Medicinemedicine.diseasePemphigoid bullouDermatologyeye diseasesLupus erythematosus systemicFemaleBullous pemphigoidsense organsbusinessDapsonemedicine.drugPediatric population
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Ripensare l’alleanza terapeutica attraverso lo studio del processo terapeutico nella cura del panico. Due terapie ad orientamento psicodinamico.

2009

Il Disturbo da Attacchi di Panico (DAP) è, sul piano clinico, una sindrome acuta e cronica, ad alta incidenza epidemiologica, che costituisce oggi, insieme alla fobia sociale e alla depressione, una delle tre maggiori cause d’invalidità della popolazione e, conseguentemente, una delle maggiori fonti di costi sociali, medici e psichiatrici (DSM-IV-TR, 2000). In questo articolo, assumendo il concetto di relazione come elemento caratterizzante il trattamento terapeutico, si cerca di connettere la manifestazione fenomenologica del panico alle modalità relazionali del soggetto e al loro significato. Si cerca di adottare questo “sguardo” anche in una prospettiva di ricerca, attraverso la “lente” …

Processo terapeutico Allenza Terapeutica DAP Terapie Psicodinamiche
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AUTOPHAGY AND APOPTOSIS MODULATION BY AQUEOUS EXTRACTS FROM LEAVES AND RHIZOMES OF Posidonia oceanica ON HEPG2 HEPATOCARCINOMA CELLS

2023

Settore CHIM/10 - Chimica Degli Alimenticell biology caspases LC3 Beclin-1 p62/SQSTM1 hsp60 BCL2 BAX BAD FOS JUN DAPK western blot flow cytometry real time PCR acidic vesicular organelles annexin bindingSettore BIO/05 - ZoologiaSettore BIO/06 - Anatomia Comparata E Citologia
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Alleanza terapeutica, Meccanismi di difesa ed Esiti nel trattamento del DAP. Analisi di una interruzione di trattamento. Uno studio single-case

2008

Settore M-PSI/08 - Psicologia ClinicaSettore M-PSI/07 - Psicologia DinamicaAlleanza terapeutica Meccanismi di difesa DAP Esiti Valutazione psicoterapia
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Sexual abuse and maltratment on child: protocols, cooperation strategies, daphne II - V.eR.S.O. (Violenza e reti sanitarie operative) Project- our ex…

2008

Sexual abuse maltratment on child daphne II - V.eR.S.O.
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Recensione di: "Longus, Daphnis and Chloe", edited by E. Bowie, Cambridge 2019

2022

Review to the volume "Longus, Daphnis and Chloe"

Textual criticism Greek novel Daphnis and Chloe Longo Sofista
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Interessos: Assignació de polítiques dels Estats jurídiques entre universalisme i regionalisme

2012

Xerrada sobre interessos deslocalitzats donada en el congrés sobre lleis regionals i internacionals realitzat a València del 13 al 15 de setembre.

conferencia ESIL SEDI law biennial conference 2012 european society of international law regional interests allocating legal policies universalism Ricardo Gosalbo Narinder Singh Andres Rönquist Daphna Shraga.5901 Ciències Polítiques
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SGLT2 inhibitors in T2D and associated comorbidities - differentiating within the class

2019

Abstract Background For patients with type 2 diabetes (T2D), cardiovascular disease (CVD) is the single most common cause of mortality. In 2008 and 2012, the Federal Drug Administration (FDA) and the European Medicines Agency (EMA) respectively mandated cardiovascular outcomes trials (CVOTs) on all new anti-diabetic agents, as prospective trials statistically powered to rule out excess cardiovascular risk in patients with T2D. Unexpectedly, some of these CVOTs have demonstrated not only cardiovascular safety, but also cardioprotective effects, as was first shown for the SGLT2 inhibitor empagliflozin in EMPA-REG OUTCOME. Expert opinion To debate newly available CVOT data and to put them into…

medicine.medical_specialtyDiabetes mellitus type 2 ; drug therapy ; Cardiovascular diseases ; drug therapy ; Canagliflozin ; therapeutic use ; Benzhydryl compounds ; therapeutic use ; Glucosides ; therapeutic use ; Sodium-Glucose Transporter 2 Inhibitors ; therapeutic useEndocrinology Diabetes and MetabolismEmpagliflozin610 Medicine & health030209 endocrinology & metabolismContext (language use)ComorbidityType 2 diabetesDiseaseCanagliflozin ; Cardiovascular disease ; Dapagliflozin ; Empagliflozin ; SGLT2 inhibitor ; Type 2 diabetes.lcsh:Diseases of the endocrine glands. Clinical endocrinology03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDiabetes mellitusCorrespondenceEmpagliflozinHumansMedicine030212 general & internal medicineCanagliflozinDapagliflozinIntensive care medicineSodium-Glucose Transporter 2 InhibitorsCanagliflozinlcsh:RC648-665business.industryIncidence616.379-008.64 [udc]Type 2 diabetesSGLT2 inhibitorGeneral MedicineDapagliflozinCardiovascular diseasePrognosismedicine.disease3. Good healthEastern europeanDiabetes Mellitus Type 2chemistryCardiovascular Diseasesbusinessmedicine.drug
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