Search results for " DELIVERY"

showing 10 items of 1045 documents

Muscle Oxygen Delivery in the Forearm and in the Vastus Lateralis Muscles in Response to Resistance Exercise: A Comparison Between Nepalese Porters a…

2020

Altitude ascending represents an intriguing experimental model reproducing physiological and pathophysiological conditions sharing hypoxemia as the denominator. The aim of the present study was to investigate fractional oxygen extraction and blood dynamics in response to hypobaric hypoxia and to acute resistance exercises, taking into account several factors including different ethnic origin and muscle groups. As part of the “Kanchenjunga Exploration & Physiology” project, six Italian trekkers and six Nepalese porters took part in a high altitude trek in the Himalayas. The measurements were carried out at low (1,450 m) and high altitude (HA; 4,780 m). Near-infrared spectroscopy (NIRS)-d…

medicine.medical_specialtyHaemodynamic responsePhysiologynear-infrared spectroscopy030204 cardiovascular system & hematologyThighlcsh:PhysiologyHypoxemia03 medical and health sciences0302 clinical medicineAltitudeForearmInternal medicinePhysiology (medical)medicineHimalayaslcsh:QP1-981business.industry030229 sport sciencesOxygenationEffects of high altitude on humanshypobaric hypoxiamedicine.anatomical_structureresistance exerciseCardiologyOxygen deliverymedicine.symptombusinesshemodynamic responseFrontiers in Physiology
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Analysis of Caesarean Section Rates Using the Robson Classification System at a University Hospital in Spain

2020

Background: The WHO recommends the use of the Robson ten-group classification system (RTGCS) as an effective monitoring and analysis tool to assess the use of caesarean sections (CS). The present study aimed to conduct an analysis of births using the RTGCS in La Ribera University Hospital over nine years and to assess the levels and trends of CS births. Methods: Retrospective study between January 1, 2010, and December 31, 2018. All eligible women were allocated in RTGCS to determine the absolute and relative contribution made by each group to the overall CS rate

medicine.medical_specialtyHealth Toxicology and Mutagenesismedicine.medical_treatmentCaesarean deliverylcsh:MedicinelaborToxicologyRobson ten-group classification systemArticleHospitals University03 medical and health sciences0302 clinical medicinePregnancyLinear regressionMedicineHumansCaesarean section030212 general & internal medicineRetrospective Studies030219 obstetrics & reproductive medicineLabor Obstetricbusiness.industryObstetricsSingletonCesarean Sectionlcsh:RRPublic Health Environmental and Occupational HealthRegression analysisRetrospective cohort studyOdds ratioUniversity hospitalParitySpaincaesarean sectionFemalebusinessObstetríciadelivery classification
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Improving Oral–Systemic Healthcare through the Interoperability of Electronic Medical and Dental Records: An Exploratory Study

2019

Objectives Electronic health records (EHRs) are rarely shared among medical and dental providers. The purpose of this study was to assess current information sharing and the value of improved electronic information sharing among physicians and dentists in Germany and the United States. Materials and Methods A survey was validated and distributed electronically to physicians and dentists at four academic medical centers. Respondents were asked anonymously about EHR use and the medical and dental information most valuable to their practice. Results There were 118 responses, a response rate of 23.2%. The majority (63.9%) of respondents were dentists and the remainder were physicians. Most res…

medicine.medical_specialtyInformation transferdentalClinical SciencesInteroperabilityDentistsExploratory researchHealth Informaticsintegratedmedical recordOral and gastrointestinalLikert scaleHealth Information ManagementClinical ResearchPhysiciansHealth carepatient safetymedicineElectronic Health RecordsHumansDental/Oral and Craniofacial Diseasehealthcare deliveryResponse rate (survey)business.industryInformation DisseminationInformation sharingDental RecordsHealth ServicesComputer Science ApplicationsTest (assessment)Good Health and Well Beingelectronic health recordsNetworking and Information Technology R&D (NITRD)Family medicinetechnologybusinessDelivery of Health CareInformation Systems
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Nanocapsules generated out of a polymeric dexamethasone shell suppress the inflammatory response of liver macrophages.

2012

Abstract Dexamethasone (DXM) is a synthetic glucocorticoid with anti-inflammatory properties. Targeted delivery of dexamethasone to inflammatory cells, e.g. macrophages and Kupffer cells represents a promising approach to minimize side effects. The aim of the present study was to induce a targeted transport of novel DXM-based biodegradable nanocapsules to phagocytic cells. Nanocapsules (NCs) consisting of a hydroxyethylated glucose polymer (hydroxyethyl starch, HES) shell with encapsulated DXM and NCs synthesized exclusively in inverse miniemulsion out of DXM were investigated. Non-parenchymal murine liver cells served as target cells. HES-DXM NCs were predominantly incorporated by Kupffer …

medicine.medical_specialtyMaterials sciencemedicine.drug_classKupffer CellsInflammatory responseBiomedical EngineeringAnti-Inflammatory AgentsPharmaceutical ScienceMedicine (miscellaneous)BioengineeringStimulationHydroxyethyl starchPharmacologybehavioral disciplines and activitiesNanocapsulesDexamethasoneProinflammatory cytokineHydroxyethyl Starch DerivativesMiceDrug Delivery SystemsNanocapsulesInternal medicinemental disordersmedicineAnimalsGeneral Materials ScienceDexamethasoneCells CulturedMice Inbred C57BLEndocrinologyMolecular MedicineCorticosteroidCytokinesFemaleGlucocorticoidmedicine.drugNanomedicine : nanotechnology, biology, and medicine
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Placenta Accreta Spectrum Disorder in a Patient with Six Previous Caesarean Deliveries: Step by Step Management

2021

The definition placenta accreta spectrum disorders (PAS) introduced by FIGO (International Federation of Gynaecology and Obstetrics) indicates an abnormal, pathological adherence or invasion of the placenta. The growing worldwide incidence of this pathological entity, and the possible serious correlated surgical risks, has caused a significant increase in attention among the scientific community. Previous caesarean delivery and presence of placenta previa are the main risk factors for the onset of PAS. Here, we present the intriguing case of a 39-year-old woman, at the 33rd week of gestation, with six previous caesarean sections and with a diagnosis of placenta previa accreta. At our referr…

medicine.medical_specialtyObstetricsbusiness.industryPlacenta accretaIncidence (epidemiology)Caesarean deliveryObstetrics and GynecologyCase ReportGynecology and obstetricsmedicine.diseasePlacenta previamedicine.anatomical_structurePlacentamedicineRG1-991GestationSpectrum disorderbusinessPathologicalreproductive and urinary physiologyCase Reports in Obstetrics and Gynecology
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Topical therapies for oral lichen planus management and their efficacy: a narrative review.

2012

Oral Lichen Planus (OLP) is a chronic inflammatory condition implicating T cell-mediated cytotoxicity, and involving oral mucosal surfaces. Several therapeutic regimens have been evaluated to treat OLP and pain related, but often without high level of evidence. Topical formulations are the favourite for the majority of cases; bioadhesive formulations have been considered very useful and practical for local drug delivery in oral mucosa, due to the increased residence time on the oral mucosa of the dosage forms and better therapeutic efficacy. In this narrative review, authors try to illustrate the current topical managements for OLP from the accessible literature on this topic. Steroids are …

medicine.medical_specialtyOral Lichen Planus topical therapy corticosteroids aloe vera retinoids hyaluronic acid phototherapy laser therapy.Time FactorsBasiliximabHyaluronic acidAdministration TopicalEfalizumabPimecrolimusRetinoidsDrug Delivery Systemsstomatognathic systemSettore MED/28 - Malattie OdontostomatologicheDrug DiscoveryOral and maxillofacial pathologymedicineCorticosteroidsHumansAloe vera; Corticosteroids; Hyaluronic acid; Laser therapy; Oral lichen planus; Phototherapy; Retinoids; Topical therapy; Drug Discovery3003 Pharmaceutical Science; PharmacologyPharmacologybusiness.industryDrug Discovery3003 Pharmaceutical ScienceMouth MucosaPhototherapymedicine.diseaseDermatologyAloe veraAlefaceptTacrolimusInfliximabstomatognathic diseasesPhotopheresisOral lichen planusQuality of LifeTopical therapyOral lichen planusLaser Therapybusinessmedicine.drugLichen Planus Oral
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Armbrust et al. 2015: Randomization questionable

2016

It is certainly possible that Cesarean delivery modifications like the one described by Armbrust, Hinkson, von Wiezsacker, and Henrich [1] are well received by mothers and partners, but some seriou...

medicine.medical_specialtyRandomizationbusiness.industryObstetrics and GynecologyRandom Allocation03 medical and health sciences0302 clinical medicineFamily medicinePediatrics Perinatology and Child HealthHumansMedicine030212 general & internal medicineCesarean deliverybusiness030217 neurology & neurosurgeryThe Journal of Maternal-Fetal & Neonatal Medicine
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Co-culture systems for vascularization — Learning from nature

2011

The endothelial cell (EC) is practically ubiquitous in the human body and forms the inner cellular lining of the entire cardiovascular system. Following tissue injury, the microcirculation becomes the stage for both the inflammatory response and the subsequent healing reaction to restore physiological function to the damaged tissue. The advent of the multidisciplinary field of Regenerative Medicine (RegMed), of which Tissue Engineering (TE) and drug delivery using modern stimuli-responsive or interactive biomaterials are important components, has opened up new approaches to the acceleration of the healing response. A central and rate-limiting role in the latter is played by the process of v…

medicine.medical_specialtyTissue EngineeringMicrocirculationRegeneration (biology)Growth factormedicine.medical_treatmentEndothelial CellsPharmaceutical ScienceBiologyRegenerative MedicineRegenerative processRegenerative medicineCoculture TechniquesSurgeryEndothelial stem cellDrug Delivery SystemsTissue engineeringIn vivoDrug deliverymedicineAnimalsHumansNeuroscienceAdvanced Drug Delivery Reviews
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A tailored telephone and email based exercise intervention induced reductions in various measures of body composition in physically inactive adults: …

2018

Obesity prevalence has increased the past decades and has become a serious public health problem. The aim of this six-month assessor-blinded, parallel-group randomized controlled trial was to assess the effect of a tailored telephone and email-based exercise intervention on various measures of body composition in a sample of apparently healthy and physically inactive adults. A total of 111 volunteering adults (40–55 yr) in Southern Norway were randomly assigned to an intervention group (IG; n = 39) or a no-information control group (CG; n = 50), by random allocation numbering. The IG received feedback on their health-related physical fitness, information on guidelines and recommendations fo…

medicine.medical_specialtyWaistPhysical fitnesslcsh:Medicine030209 endocrinology & metabolismHealth InformaticsBody compositionlaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawIntervention (counseling)medicine030212 general & internal medicineCG Control GroupCRF cardiorespiratory fitnessbusiness.industryPublic healthWC Waist Circumferencelcsh:RWeight changeWeight changePublic Health Environmental and Occupational HealthRegular Articlemedicine.diseaseObesityIG Intervention GroupPhysical therapyFPskf Fat Percentage by skinfoldsBMI Body Mass IndexbusinessMixed delivery modesBody mass indexPreventive Medicine Reports
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Is it time to be concerned about the effects of e-cigarettes on cardiovascular health?

2018

medicine.medical_specialtybusiness.industryCardiovascular healthelectronic nicotine delivery systemhealthE-cigarette; cardiovascular disease; electronic nicotine delivery system; health; myocardial infarctionGeneral Medicine030204 cardiovascular system & hematologymedicine.disease03 medical and health sciencesE-cigarettemyocardial infarction0302 clinical medicineText miningcardiovascular diseaseInternal Medicinemedicine030212 general & internal medicineMyocardial infarctionCardiology and Cardiovascular MedicinebusinessIntensive care medicineExpert Review of Cardiovascular Therapy
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