Search results for " DEMENTIA"

Ageing and sexuality

2016

Abstract Sexuality is a dimension that concerns human health with profound implications not only in the biological and psychological aspects, but also in the social and cultural dimensions, affecting all ages of life. Sexuality in old age is still conditioned by biases, prejudices and from a stereotyped vision, which considered older people as “asexual”, in spite of several studies and surveys showing that older persons have sexual potential to express. In population surveys, a fair number of men and women aged over 60 years reported having sex at least once a month. The most influential predictor of sexual activity seems to be the physical health in older men, and the quality of the relati…

Use of statins and the risk of dementia and mild cognitive impairment: a systematic review and meta-analysis

2018

AbstractWe conducted a systematic review and meta-analysis to investigate whether the use of statins could be associated with the risk of all-caused dementia, Alzheimer’s disease (AD), vascular dementia (VaD), and mild cognitive impairment (MCI). Major electronic databases were searched until December 27th, 2017 for studies investigating use of statins and incident cognitive decline in adults. Random-effects meta-analyses calculating relative risks (RRs) were conducted to synthesize effect sizes of individual studies. Twenty-five studies met eligibility criteria. Use of statins was significantly associated with a reduced risk of all-caused dementia (k = 16 studies, adjusted RR (aRR) = 0.849…

Identification of three novel progranulin mutations in a series of patients affected by sporadic and familial frontotemporal lobar de generation. Pla…

2009

Lexical Substitution and Paraphasia in Advanced Dementia of the Alzheimer Type

2017

Abstract The paper presents the case study of lexical selection in Alzheimer-type dementia. Lexical substitutions in poem recitation and conversations of a Russian speaker, who suffered Alzheimer-type dementia, were analyzed on the background of the lexical retrieval and slip-of-the-tongue phenomena. The classification of the substitutions is worked out on the basis of the links between a target word and its substitutions. The current context plays an essential role as natural priming for a substitution in a poem recitation. Some words have predisposition to be lost; the units belong to the figurative language or to the category of infrequent lexemes. In conversation, the patient masked fai…

The “Diabetes Comorbidome”: A Different Way for Health Professionals to Approach the Comorbidity Burden of Diabetes

2022

(1) Background: The disease burden related to diabetes is increasing greatly, particularly in older subjects. A more comprehensive approach towards the assessment and management of diabetes’ comorbidities is necessary. The aim of this study was to implement our previous data identifying and representing the prevalence of the comorbidities, their association with mortality, and the strength of their relationship in hospitalized elderly patients with diabetes, developing, at the same time, a new graphic representation model of the comorbidome called “Diabetes Comorbidome”. (2) Methods: Data were collected from the RePoSi register. Comorbidities, socio-demographic data, severity and comorbidit…