Search results for " DFT"

showing 10 items of 97 documents

Triphenylphosphane Pt(II) complexes containing biologically active natural polyphenols: Synthesis, crystal structure, molecular modeling and cytotoxi…

2016

Platinum complexes bearing phosphane ligands in cis configuration with deprotonated flavonoids (3-hydroxyflavone, quercetin) and deprotonated ethyl gallate were synthesized starting from cis-[PtCl2(PPh3)(2)]. In all cases, O,O' chelate structures were obtained. While quercetin and ethyl gallate complexes are quite stable in solution, the 3-hydroxyflavonate complex undergoes a slow aerobic photodegradation in solution with formation of salicylic and benzoic acids. The X-ray diffraction structures of quercetin and ethyl gallate complexes are reported. Cell cycle studies (in the dark) of the complexes in two human cell lines revealed that the cytotoxic activity of the complex bearing 3-hydroxy…

Models MolecularPlatinum(II) complexesOrganoplatinum CompoundsMolecular modelStereochemistryPlatinum(II) complexes; Cytotoxic activity; Natural polyphenols; Flavonoids; DFTEthyl gallateCrystal structureCytotoxic activity; DFT; Flavonoids; Natural polyphenols; Platinum(II) complexesCrystallography X-Ray010402 general chemistry01 natural sciencesBiochemistryMedicinal chemistryDFTInorganic ChemistryHydrolysischemistry.chemical_compoundDeprotonationHumansChelationPhotodegradationCytotoxic activity DFT Flavonoids Natural polyphenols Platinum(II) complexesFlavonoidsCytotoxic activityCytotoxins010405 organic chemistryChemistryPolyphenols0104 chemical sciencesMCF-7 CellsNatural polyphenolsCis–trans isomerism
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Understanding the Mechanism of the Intramolecular Stetter Reaction. A DFT Study

2012

The mechanism of the N-heterocyclic carbene (NHC)-catalyzed intramolecular Stetter reaction of salicylaldehyde 1 to yield chromanone 3 has been theoretically studied at the B3LYP/6-31G** level. This NHC-catalyzed reaction takes place through six elementary steps, which involve: (i) formation of the Breslow intermediate IN2; (ii) an intramolecular Michael-Type addition in IN2 to form the new C-C s bond; and (iii) extrusion of the NHC catalyst from the Michael adduct to yield chromanone 3. Analysis of the relative free energies in toluene indicates that while formation of Breslow intermediate IN2 involves the rate-determining step of the catalytic process, the intramolecular Michael-type addi…

Models MolecularStereochemistryPharmaceutical Scienceintramolecular Stetter reactionDFT calculationsArticleCatalysisAnalytical ChemistryStereocenterCatalysislcsh:QD241-441chemistry.chemical_compoundlcsh:Organic chemistryComputational chemistryHeterocyclic CompoundsDrug Discoveryintramolecular Michael additionorganocatalysisN-heterocyclic carbenesPhysical and Theoretical ChemistrymechanismsChemistryOrganic ChemistryStetter reactionorganocatalysis; <em>N</em>-heterocyclic carbenes; <em>umpolung</em> reactivity; intramolecular Stetter reaction; intramolecular Michael addition; mechanisms; DFT calculationsSalicylaldehydeChemistry (miscellaneous)Yield (chemistry)OrganocatalysisIntramolecular forceumpolung reactivityMolecular MedicineCarbeneMethaneMolecules
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Structural and Molecular Characterization of meso-Substituted Zinc Porphyrins: A DFT Supported Study

2011

Structural parameters of a range of over 100 meso-substituted zinc porphyrins were reviewed and compared to show how far the nature of the functional group may affect the interatomic distances and bond angles within the porphyrin core. It was proved that even despite evident deformations of the molecular structure, involving twisting of the porphyrin's central plane, the coupled π-bonding system remains flexible and stable. DFT calculations were applied to a number of selected porphyrins representative for the reviewed compounds to emphasize the relevance of theoretical methods in structural investigations of complex macrocyclic molecular systems. Experimental and DFT-simulated IR spectral …

Models Molecularzinc porphyrins; molecular structure; DFT theoretical calculations; IR spectraPorphyrinsSpectrophotometry InfraredStereochemistrySurface PropertiesPharmaceutical Sciencechemistry.chemical_elementInfrared spectroscopyContext (language use)molecular structureZincCrystallography X-RayVibrationArticleAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compoundDFT theoretical calculationslcsh:Organic chemistryComputational chemistryDrug Discoveryzinc porphyrins molecular structure DFT theoretical calculations IR spectraSpectroscopy Fourier Transform InfraredMoleculeMoietyComputer SimulationPyrrolesPhysical and Theoretical ChemistryIR spectraOrganic ChemistryPorphyrinzinc porphyrinsZincMolecular geometrychemistryModels ChemicalChemistry (miscellaneous)Functional groupMicroscopy Electron ScanningMolecular MedicineQuantum TheoryMolecules
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Hydrogen activation on N‐doped carbon networks

2014

NCNT DFT
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Ab initio simulations on charged interstitial oxygen migration in corundum

2018

We have performed this work within the framework of the EUROfusion Consortium receiving funding from the European grant agreement 633053. The views and opinions expressed herein do not necessarily reflect those of the European Commission. Authors thank R. Vila, A.I. Popov, A. Luchshik and R.A. Evarestov for fruitful discussions. To carry out large-scale calculations, we have used the HPC supercomputer at Stuttgart University (Germany)

Nuclear and High Energy PhysicsMaterials scienceAb initiochemistry.chemical_elementCorundum02 engineering and technologyengineering.material01 natural sciences7. Clean energyMolecular physicsOxygenIonCondensed Matter::Materials ScienceHybrid DFT-LCAO calculationsCondensed Matter::Superconductivity0103 physical sciences:NATURAL SCIENCES:Physics [Research Subject Categories]010306 general physicsInstrumentationα-Al2O3(corundum sapphire)Charged oxygen interstitial diffusion021001 nanoscience & nanotechnologychemistryLinear combination of atomic orbitalsengineeringSapphireDensity functional theory0210 nano-technologyNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
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Hybrid density functional calculations of hyperfine coupling tensor for hole-type defects in MgAl2O4

2020

This work has been performed within the framework of the EUROfusion Enabling Research project: ENR-MFE19.ISSP-UL-02 “Advanced experimental and theoretical analysis of defect evolution and structural disordering in optical and dielectric materials for fusion application”. The views and opinions expressed herein do not necessarily reflect those of the European Commission.

Nuclear and High Energy PhysicsMaterials scienceMgAl2O4 (spinel)02 engineering and technologyType (model theory)engineering.material010402 general chemistry01 natural sciencesMolecular physicsResonance (particle physics)Spectral linelaw.inventionParamagnetismlaw:NATURAL SCIENCES:Physics [Research Subject Categories]TensorElectron paramagnetic resonanceInstrumentationHole-type defects (V-centres)Relaxation (NMR)Spinel021001 nanoscience & nanotechnology3. Good health0104 chemical sciencesHybrid DFT calculations (B3LYP)engineering0210 nano-technologyNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
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Solution of universal nonrelativistic nuclear DFT equations in the Cartesian deformed harmonic-oscillator basis. (IX) HFODD (v3.06h) : a new version …

2021

We describe the new version (v3.06h) of the code HFODD that solves the universal nonrelativistic nuclear DFT Hartree-Fock or Hartree-Fock-Bogolyubov problem by using the Cartesian deformed harmonic-oscillator basis. In the new version, we implemented the following new features: (i) zero-range three- and four-body central terms, (ii) zero-range three-body gradient terms, (iii) zero-range tensor terms, (iv) zero-range isospin-breaking terms, (v) finite-range higher-order regularized terms, (vi) finite-range separable terms, (vii) zero-range two-body pairing terms, (viii) multi-quasiparticle blocking, (ix) Pfaffian overlaps, (x) particle-number and parity symmetry restoration, (xi) axializatio…

Nuclear and High Energy Physics[PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th]Nuclear Theoryharmonic-oscillator basisMEAN-FIELDFOS: Physical sciencesPfaffianPART114 Physical sciences01 natural sciencesSeparable spacelaw.inventionNuclear Theory (nucl-th)värähtelytlawFINITE-RANGEBOGOLYUBOV EQUATIONS0103 physical sciencesCartesian coordinate systemTensornuclear DFT010306 general physicsHarmonic oscillatorMathematical physicsPARAMETRIZATIONPhysicsBasis (linear algebra)010308 nuclear & particles physicstiheysfunktionaaliteoriatietokoneohjelmatParity (physics)HARTREE-FOCK EQUATIONSHFODDGROUND-STATEPairingnumeerinen analyysiFORCESydinfysiikka
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Synthesis, characterization, and in vitro antimicrobial activity of organotin(IV) complexes with triazolo-pyrimidine ligands containing exocyclic oxy…

2005

Abstract Tri-organotin(IV) complexes of the triazolo-pyrimidine derivatives 4,5-dihydro-5-oxo-[1,2,4]triazolo-[1,5 a ]pyrimidine (5HtpO), 4,7-dihydro-5-methyl-7-oxo-[1,2,4]triazolo-[1,5 a ]pyrimidine (HmtpO), and 4,5,6,7-tetrahydro-5,7-dioxo-[1,2,4]triazolo-[1,5 a ]pyrimidine (H 2 tpO 2 ), and the diorganotin derivative n -Bu 2 Sn(tpO 2 ), were synthesized and characterized by means of infrared and 119 Sn Mossbauer spectroscopy. In all the complexes obtained the triazolopyrimidines act as multidentate ligands producing polymeric structures. A trigonal bipyramidal arrangement of the ligands around the tin atom is proposed for triorganotin(IV) derivatives, with organic groups on the equatoria…

ONIOMDenticityPyrimidineStereochemistryLigandOrganic ChemistryDFT calculationTriazolopyrimidine; Organotin(IV); Mossbauer; DFT calculations; Antimicrobial activityOrganotin(IV)Antimicrobial activityBiochemistryMedicinal chemistryMossbauerInorganic Chemistrychemistry.chemical_compoundTrigonal bipyramidal molecular geometrychemistryMössbauer spectroscopyOctahedral molecular geometryMaterials ChemistryTriazolopyrimidineChelationPhysical and Theoretical ChemistryJournal of Organometallic Chemistry
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New light on an old debate: Does the RCN-PtCl2 bond include any back-donation? RCN←PtCl2 backbonding: Vs. the IR ν CN blue-shift dichotomy in organon…

2019

For a series of organonitrile [RCN (R = Me, CF3, Ph, CH3Ph, CF3Ph)] ligands, the nature of the N-Pt bond in the related cis-/trans-(RCN)2PtCl2 complexes has been computationally investigated by Density Functional Theory. A fragment based bond analysis has been performed in the canonical Kohn-Sham molecular orbitals framework, and it has been ultimately assessed that this bond is characterized both by N→Pt σ and by N←Pt π contributions. Voronoi Deformation Density charges further confirms the occurrence of N←Pt π interactions. Moreover, the Energy Decomposition Analysis-Natural Orbital for Chemical Valence (EDA-NOCV) method shows that the strength of the N←Pt π interaction is not negligible …

Organonitriles/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energySettore CHIM/03 - Chimica Generale E InorganicaOrganonitriles DFT Energy Decomposition Analysis-Natural Orbital for Chemical Valencebond.infraredSDG 7 - Affordable and Clean EnergyEDA-NOCVPlatinum(II)organonitrileDFTEnergy Decomposition Analysis-Natural Orbital for Chemical Valence
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Structure Sensitivity of 2‐Methyl--butyn-2-ol Hydrogenation on Pd: Computational and Experimental Modeling

2014

Palladium catalists structure sensitivity DFT calculations
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