Search results for " DOC"

A framework to identify primitives that represent usability within Model-Driven Development methods

2014

Context: Nowadays, there are sound methods and tools which implement the Model-Driven Development approach (MDD) satisfactorily. However, MDD approaches focus on representing and generating code that represents functionality, behaviour and persistence, putting the interaction, and more specifically the usability, in a second place. If we aim to include usability features in a system developed with a MDD tool, we need to extend manually the generated code. Objective: This paper tackles how to include functional usability features (usability recommendations strongly related to system functionality) in MDD through conceptual primitives. Method: The approach consists of studying usability guide…

La reapertura de la Biblioteca Ambrosiana de Milán

1996

Education Students’ Use of Collaborative Writing Tools in Collectively Reflective Essay Papers

2014

Published version of an article in the journal: Journal of Information Technology Education: Research. Also available from the publisher at: http://www.jite.org/documents/Vol13/JITEv13ResearchP091-120Brodahl0463.pdf Open Access Google Docs and EtherPad are Web 2.0 tools providing opportunity for multiple users to work online on the same document consecutively or simultaneously. Over the last few years a number of research papers on the use of these collaborative tools in a teaching and learning environment have been published. This work builds on that of Brodahl, Hadjerrouit, and Hansen (2011) expanding its case study. The theoretical framework is the same as the one underlying Brodahl et a…

Le renforcement en trompe-l’œil du droit d’accès aux documents administratifs. Note sur CE, 8 févr. 2023, n° 452521, Ville de Paris

2023

Sous réserve des dispositions de l’article L. 311-6 du code des relations entre le public et l’administration qui protègent notamment la vie privée, le secret médical et le secret des affaires en prévoyant l’occultation de certaines mentions, des notes de frais et reçus de déplacements ainsi que des notes de frais de restauration et reçus de frais de représentation d’élus locaux ou d’agents publics constituent des documents administratifs, communicables à toute personne qui en fait la demande. La Ville de Paris ne pouvait donc s’opposer à leur communication au demandeur. Le présent arrêt précise la portée du droit d’accès aux documents administratifs en confirmant que les notes de frais et …

Open availability of articles and raw research data in spanish pediatrics journals

2015

[EN]: Introduction: The open Access to publications and the raw data allows its re-use and enhances the advancement of science. The aim of this paper is to identify these practices in Spanish pediatrics journals. Method: We reviewed the author's instructions in 13 Spanish pediatrics journals, identifyingtheir open access and deposit policy. Results: Eight journals allow open access without restriction, and 5 provide information on theability to re-use and depositing data in repositories or websites. Conclusions: Most of the journals have open access, but do not promote the deposit of additionalmaterial or articles in repositories or websites.

Profiles of University Professors in Spain for the European Higher Education Area (EHEA)

2009

This paper presents the findings of a research study of professors’ profiles for the European Higher Education Area (EHEA) conducted in five spanish universities. Through the application of qualitative methods of inquiry, the perceptions of several groups of university professors over the principal teaching qualifications necessary for the coordination of higher education throughout the European Union have been obtained. Data analysis indicates a significant discrepancy between actual Spanish professors and those required by EHEA. It has also made possible the detailed description of teaching competency profiles that professors believe to be fundamental for the new functions demanded of the…

La competenza docimologica per la valorizzazione dei talenti. Una ricerca con i futuri docenti di scuola primaria e dell’infanzia

2018

Educating gifted students must be a priority for educators and education systems if society is to capitalise on their potential to contribute to an economical and sustain- able future. Given the importance of teachers in supporting academic achievement, educating preservice teachers on how to cater for gifted students commences the process as they can foster the implementation of current teaching practices that draw on sub- stantial research into the education of gifted children. If Evaluation process becomes an instrument for the development of talent in the classroom pre-service teacher training in docimological skill is necessary. In the ed- ucational field, talent and excellence find th…

Il modello flipped learning per promuovere lo sviluppo delle competenze docimologiche dei futuri insegnanti di scienze della formazione primaria.

2017

La ricerca intende far riflettere sul tema della formazione dei futuri insegnanti di scuola primaria, a partire dall’impiego del metodo innovativo della flipped classroom, all’interno dell’insegnamento di Docimologia del secondo anno del corso di laurea in Scienze della Formazione Primaria e del corrispondente laboratorio. Il lavoro presenta i presupposti teorici, gli obiettivi e le modalità operative di un percorso che ha visto l’impiego della metodologia flipped per promuovere lo sviluppo delle competenze docimologiche all’università. Attraverso l’utilizzo del modello della flipped si è inteso favorire l’acquisizione dei principali contenuti della Docimologia; consentire agli studenti non…

Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics

2021

To date, computational approaches have been recognized as a key component in drug design and discovery workflows. Developed to help researchers save time and reduce costs, several computational tools have been developed and implemented in the last twenty years. At present, they are routinely used to identify a therapeutic target, understand ligand–protein and protein–protein interactions, and identify orthosteric and allosteric binding sites, but their primary use remains the identification of hits through ligand-based and structure-based virtual screening and the optimization of lead compounds, followed by the estimation of the binding free energy. The repurposing of an old drug for the tr…

Structure‐Activity Relationships of Benzamides and Isoindolines Designed as SARS‐CoV Protease Inhibitors Effective against SARS‐CoV‐2

2020

Abstract Inhibition of coronavirus (CoV)‐encoded papain‐like cysteine proteases (PLpro) represents an attractive strategy to treat infections by these important human pathogens. Herein we report on structure‐activity relationships (SAR) of the noncovalent active‐site directed inhibitor (R)‐5‐amino‐2‐methyl‐N‐(1‐(naphthalen‐1‐yl)ethyl) benzamide (2 b), which is known to bind into the S3 and S4 pockets of the SARS‐CoV PLpro. Moreover, we report the discovery of isoindolines as a new class of potent PLpro inhibitors. The studies also provide a deeper understanding of the binding modes of this inhibitor class. Importantly, the inhibitors were also confirmed to inhibit SARS‐CoV‐2 replication in …