Search results for " Database"

showing 10 items of 684 documents

A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines

2014

Cancer cell lines are a tremendous resource for cancer biology and therapy development. These multipurpose tools are commonly used to examine the genetic origin of cancers, to identify potential novel tumor targets, such as tumor antigens for vaccine devel-opment, and utilized to screen potential therapies in preclinical studies. Mutations, gene expression, and drug sensitivity have been determined for many cell lines using next-generation sequencing (NGS). However, the human leukocyte antigen (HLA) type and HLA expression of tumor cell lines, characterizations necessary for the development of cancer vaccines, have remained largely incomplete and, such information, when available, has been …

HLA typeCCLE Cancer Cell Line Encyclopediamedicine.medical_treatmentCOSMIC Catalog of Somatic Mutations in CancerImmunologyBRENDA BRaunschweig ENzyme DatabaseSNV single nucleotide variationRNA-SeqHuman leukocyte antigenBiologynsSNV non synonymous SNVTranscriptomeLoss of heterozygosityAntigenGenotypemedicineImmunology and AllergyRNA-SeqRNA-Seq RNA SequencingOriginal ResearchGeneticsHLA expressionneoepitopescancer cell linesSRA Sequence Read ArchiveCancerImmunotherapymedicine.diseaseHLA Human Leukocyte AntigenOncologyRPKM reads per kilobase of exon model per million mapped readsIEDB Immune Epitope Databasesomatic mutationsimmunotherapyDLBCL diffuse large B-cell lymphomaNGS Next Generation SequencingOncoImmunology
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ORIGIN: metal creation and evolution from the cosmic dawn

2012

Herder, Jan-Willem den et al.

HOT INTERGALACTIC MEDIUMUNIVERSEChemical evolutionMission7. Clean energy01 natural sciencesSpectral lineSettore FIS/05 - Astronomia E Astrofisica010303 astronomy & astrophysicsmedia_commonPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)NUCLEOSYNTHESISCOSMIC cancer databaseClusters of galaxiesSatellite MissionEpoch (reference date)Astrophysics::Instrumentation and Methods for AstrophysicsFORESTGALAXIESGamma-ray burstsAstrophysics - Instrumentation and Methods for AstrophysicsAstrophysics - High Energy Astrophysical PhenomenaX-ray Mission Gamma-ray bursts Clusters of galaxies Warm-hot intergalactic medium Chemical evolutionWarm-hot intergalactic mediumAstrophysics - Cosmology and Nongalactic AstrophysicsAstrophysics and AstronomyStructure formationCosmology and Nongalactic Astrophysics (astro-ph.CO)Clusters of galaxiemedia_common.quotation_subjectAstrophysics::High Energy Astrophysical PhenomenaREDSHIFTFOS: Physical sciencesAstrophysics::Cosmology and Extragalactic AstrophysicsX-ray Mission Gamma-ray bursts Clusters of galaxies Warm-hot intergalactic medium Chemical evolutionABSORPTION-SPECTRA010309 opticsX-rayYIELDS0103 physical sciencesGamma-ray burstInstrumentation and Methods for Astrophysics (astro-ph.IM)X-ray; Mission; Gamma-ray bursts; Clusters of galaxies; Warm-hot intergalactic medium; Chemical evolutionAstronomyAstronomy and AstrophysicsRedshiftGalaxyUniverse13. Climate actionChemical evolution; Clusters of galaxies; Gamma-ray bursts; Mission; Warm-hot intergalactic medium; X-ray; Astronomy and Astrophysics; Space and Planetary ScienceSpace and Planetary ScienceGamma-ray burstCLUSTERSExperimental Astronomy
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Hemostatic agents used in apical surgery: a review

2011

Objective: A review was made of the current literature on hemostatic agents used in apical surgery in order to determine their effectiveness and adverse effects. Material and methods: The main search terms used were: endodontic surgery, apicoectomy, apical surgery, periradicular surgery, hemostasis, hemostatic agents, and bleeding control. The authors searched the Medline database for articles published up to 1 September 2010. Experimental and clinical studies comparing the effectiveness and/ or adverse effects of two or more hemostatic agents and published between 2000 and 2010 were included in the review. Results: Four studies were analyzed: two clinical studies and two experimental studi…

Hemostatic Agentmedicine.medical_specialtybusiness.industrymedicine.medical_treatmentOdontología:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludSurgeryClinical trialBlood pressureApical surgeryHemostasisApicoectomyUNESCO::CIENCIAS MÉDICASmedicineAdverse effectbusinessMedline databaseGeneral Dentistry
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Probing Planck scale physics with IceCube

2005

Neutrino oscillations can be affected by decoherence induced e.g. by Planck scale suppressed interactions with the space-time foam predicted in some approaches to quantum gravity. We study the prospects for observing such effects at IceCube, using the likely flux of TeV antineutrinos from the Cygnus spiral arm. We formulate the statistical analysis for evaluating the sensitivity to quantum decoherence in the presence of the background from atmospheric neutrinos, as well as from plausible cosmic neutrino sources. We demonstrate that IceCube will improve the sensitivity to decoherence effects of ${\cal O}(E^2/M_{\rm Pl})$ by 17 orders of magnitude over present limits and, moreover, that it ca…

High Energy Physics - TheoryAstrofísicaNuclear and High Energy PhysicsParticle physicsField theory (Physics)Quantum decoherenceAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesCosmic rayGeneral Relativity and Quantum Cosmology (gr-qc)Astrophysics7. Clean energy01 natural sciencesGeneral Relativity and Quantum CosmologyHigh Energy Physics - Phenomenology (hep-ph)0103 physical sciencesTeoria quànticaNeutrinsSensitivity (control systems)Neutrinos010306 general physicsNeutrino oscillationPhysicsCOSMIC cancer database010308 nuclear & particles physicsAstrophysics (astro-ph)Teoria de camps (Física)High Energy Physics - PhenomenologyHigh Energy Physics - Theory (hep-th)Orders of magnitude (time)13. Climate actionQuantum theoryQuantum gravityNeutrinoPhysical Review D
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CORAL Server and CORAL Server Proxy: Scalable Access to Relational Databases from CORAL Applications

2011

The CORAL software is widely used at CERN for accessing the data stored by the LHC experiments using relational database technologies. CORAL provides a C++ abstraction layer that supports data persistency for several backends and deployment models, including local access to SQLite files, direct client access to Oracle and MySQL servers, and read-only access to Oracle through the FroNTier web server and cache. Two new components have recently been added to CORAL to implement a model involving a middle tier "CORAL server" deployed close to the database and a tree of "CORAL server proxy" instances, with data caching and multiplexing functionalities, deployed close to the client. The new compon…

HistoryDatabasebusiness.industryComputer scienceRelational databasecomputer.software_genreMultiplexingProxy (climate)OracleComputer Science ApplicationsEducationComputing and ComputersTree (data structure)SoftwareScalabilityOperating systemArchitecturebusinesscomputer
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CORAL and COOL during the LHC long shutdown.

2013

CORAL and COOL are two software packages used by the LHC experiments for managing detector conditions and other types of data using relational database technologies. They have been developed and maintained within the LCG Persistency Framework, a common project of the CERN IT department with ATLAS, CMS and LHCb. This presentation reports on the status of CORAL and COOL at the time of CHEP2013, covering the new features and enhancements in both packages, as well as the changes and improvements in the software process infrastructure. It also reviews the usage of the software in the experiments and the outlook for ongoing and future activities during the LHC long shutdown (LS1) and beyond. CORA…

HistoryEngineeringLarge Hadron Colliderbusiness.industryRelational databaseShutdowncomputer.software_genreComputer Science ApplicationsEducationComputing and ComputersSoftware development processSoftwareOperating systembusinesscomputer
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LCG Persistency Framework (CORAL, COOL, POOL): Status and Outlook

2011

The LCG Persistency Framework consists of three software packages (POOL, CORAL and COOL) that address the data access requirements of the LHC experiments in several different areas. The project is the result of the collaboration between the CERN IT Department and the three experiments (ATLAS, CMS and LHCb) that are using some or all of the Persistency Framework components to access their data. The POOL package is a hybrid technology store for C++ objects, using a mixture of streaming and relational technologies to implement both object persistency and object metadata catalogs and collections. POOL provides generic components that can be used by the experiments to store both their event data…

HistoryLarge Hadron ColliderDatabaseRelational databasebusiness.industryComputer sciencecomputer.software_genreComputing and ComputersComputer Science ApplicationsEducationAbstraction layerMetadataData accessSoftwarePackage development processbusinesscomputerJournal of Physics: Conference Series
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Indización y uso de los Descriptores MeSH en Hospitalización a Domicilio

2017

Objetivo: Analizar la utilización de los Descriptores, como Major Topic, en la indización de los artículos sobre Hospitalización Domiciliaria en la base de datos MEDLINE.Método: Estudio descriptivo transversal de los registros de indización recogidos en la base de datos MEDLINE (vía PubMed) hasta 2016. El término utilizado, como descriptor principal para la búsqueda fue «Home Care Services, Hospital-Based».El método de muestreo fue la aleatorización simple sin reemplazo, tomando como base el número total de referencias obtenidas (tamaño muestral 386).Resultados: Se observaron diferencias significativas en la utilización de los Descriptores asociados a hospitalización a domicilio. La compara…

Home hospitalizationTelemedicineInformation retrievalGeographySample size determinationSearch engine indexingMeSH DescriptorsSubject (documents)Medline databaseCartographyTerm (time)Hospital a Domicilio
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Database to Ontology Mapping Patterns in RDB2OWL Lite

2016

We describe the RDB2OWL Lite language for relational database to RDF/OWL mapping specification and discuss the architectural and content specification patterns arising in mapping definition. RDB2OWL Lite is a simplification of original RDB2OWL with aggregation possibilities and order-based filters removed, while providing in-mapping SQL view definition possibilities. The mapping constructs and their usage patterns are illustrated on mapping examples from medical domain: medicine registries and hospital information system. The RDB2OWL Lite mapping implementation is offered both via translation into D2RQ and into standard R2RML mapping notations.

Hospital information systemOpen Biomedical OntologiesInformation retrievalComputer scienceViewRelational databaseSemantic integrationcomputer.file_formatRDFNotationcomputerDomain (software engineering)
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Combinatorial Identification of Hydrides in a Ligated Ag40 Nanocluster with Noncompact Metal Core

2019

No formation of bulk silver hydride has been reported. Until very recently, only a few silver nanoclusters containing hydrides have been successfully prepared. However, due to the lack of effective techniques and also poor stability of hydride-containing Ag nanoclusters, the identification of hydrides' location within Ag nanoclusters is challenging and not yet achieved, although some successes have been reported on clusters of several Ag atoms. In this work, we report a detailed structural and spectroscopic characterization of the [Ag40(DMBT)24(PPh3)8H12]2+ (Ag40H12) cluster (DMBT = 2,4-dimethylbenzenethiol). The metal framework consists of three concentric shells of Ag8@Ag24@Ag8, which can…

HydrideChemistryGeneral ChemistryElectron010402 general chemistry01 natural sciencesBiochemistryCatalysis0104 chemical sciencesCharacterization (materials science)NanomaterialsNanoclustersNMR spectra databaseMetalCrystallographyColloid and Surface Chemistryvisual_artvisual_art.visual_art_mediumCluster (physics)Journal of the American Chemical Society
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