Search results for " Design"
showing 10 items of 5050 documents
Acute Effect of Alcohol Intake on Cardiovascular Autonomic Regulation During the First Hours of Sleep in a Large Real-World Sample of Finnish Employe…
2018
Background Sleep is fundamental for good health, and poor sleep has been associated with negative health outcomes. Alcohol consumption is a universal health behavior associated with poor sleep. In controlled laboratory studies, alcohol intake has been shown to alter physiology and disturb sleep homeostasis and architecture. The association between acute alcohol intake and physiological changes has not yet been studied in noncontrolled real-world settings. Objective The aim of this study was to assess the effects of alcohol intake on the autonomic nervous system (ANS) during sleep in a large noncontrolled sample of Finnish employees. Methods From a larger cohort, this study included 4098 su…
Hormone Replacement Therapy Associated White Blood Cell DNA Methylation and Gene Expression are Associated With Within-Pair Differences of Body Adipo…
2015
The loss of estrogen during menopause causes changes in the female body, with wide-ranging effects on health. Estrogen-containing hormone replacement therapy (HRT) leads to a relief of typical menopausal symptoms, benefits bone and muscle health, and is associated with tissue-specific gene expression profiles. As gene expression is controlled by epigenetic factors (including DNA methylation), many of which are environmentally sensitive, it is plausible that at least part of the HRT-associated gene expression is due to changes in DNA methylation profile. We investigated genome-wide DNA methylation and gene expression patterns of white blood cells (WBCs) and their associations with body compo…
Clinical retrospective study of dental implant removal : do patients who require implant removal desire implant prosthesis again?
2020
Background This study investigated the causes of dental implant removal due to complications, and examined whether patients who had dental implant removal desired re-implant prosthesis treatments. Material and Methods A retrospective case–control study was conducted on patients who had their dental implants removed. We investigated whether the removed dental implant was replaced with other implant prostheses. Age, sex, diabetes, smoking, implant site distribution, reason for implant removal, and blade and root-form implants were categorized as predictive variables. The outcome variable was desire for re-implantation or use of other prosthetic methods after implant removal. A logistic regres…
New intraocular lens for achromatizing the human eye.
2007
To describe the design of a new intraocular lens (IOL) capable of correcting spherical and chromatic aberrations when implanted in the human eye.University of Murcia, Murcia, and University of Valencia, Valencia, Spain.A hybrid singlet achromatic IOL was designed. The IOL has a combination of a refractive and a diffractive surface, with 1 of the surfaces being aspherical. Optical simulations were used to model the polychromatic modulation transfer function (MTF) in pseudophakic eyes to explain the differences in optical quality afforded by the achromatic IOL. Parameters such as focus shift, optical path difference, through-focus, and robustness to tilt and decentering of achromatic IOLs wer…
Group 1 ITI Consensus Report: The influence of implant length and design and medications on clinical and patient-reported outcomes
2018
The following article: Jung, R.E., Al-Nawas, B., Araujo, M., Avila-Ortiz, G., Barter, S., Brodala, N., ... Windisch, P. (2018). Group 1 ITI Consensus Report: The influence of implant length and design and medications on clinical and patient-reported outcomes. Clinical Oral Implants Research, 29(S16), 69-77, can be accessed at https://doi.org/10.1111/clr.13342. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Objectives: The aim of Working Group 1 was to address the influence of different local (implant length, diameter, and design) and systemic (medications) factors on clinical, radiographic, and patient‐re…
Stability of radial head and neck fractures: a biomechanical study of six fixation constructs with consideration of three locking plates.
2007
Open reduction and internal fixation of radial neck fractures can lead to secondary loss of reduction and nonunion due to insufficient stability. Nevertheless, there are only a few biomechanical studies about the stability achieved by different osteosynthesis constructs.Forty-eight formalin-fixed, human proximal radii were divided into 6 groups according to their bone density (measured by dual-energy x-ray absorptiometry). A 2.7-mm gap osteotomy was performed to simulate an unstable radial neck fracture, which was fixed with 3 nonlocking implants: a 2.4-mm T plate, a 2.4-mm blade plate, and 2.0-mm crossed screws, and 3 locking plates: a 2.0-mm LCP T plate, a 2.0-mm 6x2 grid plate, and a 2.0…
Mid- to Long-Term Outcomes of Cervical Disc Arthroplasty versus Anterior Cervical Discectomy and Fusion for Treatment of Symptomatic Cervical Disc Di…
2015
Purpose This study aimed to investigate the mid- to long-term outcomes of cervical disc arthroplasty (CDA) versus anterior cervical discectomy and fusion (ACDF) for the treatment of 1-level or 2-level symptomatic cervical disc disease. Methods Medline, Embase, and the Cochrane Central Register of Controlled Trials databases were searched to identify relevant randomized controlled trials that reported mid- to long-term outcomes (at least 48 months) of CDA versus ACDF. All data were analyzed by Review Manager 5.3 software. The relative risk (RR) and 95% confidence intervals (CIs) were calculated for dichotomous variables. The weighted mean difference (WMD) and 95%CIs were calculated for conti…
Tematiskā sulu bāra interjera izveides principi
2016
Diplomdarbā “Tematiskā sulu bāra interjera izveides principi”, analizējot pieejamo literatūru un informācijas avotus, tiek apskatīta bāru un, īpaši, sulu bāru vēsturiskā attīstība. Izpētīti interjeru veidojošie dizaina faktori, kā arī merčendaizinga noteikumi sulu bāra izveidei. Empīriskajā daļā tiek veikts salīdzinošais pētījums, analizējot sulu bāru interjerus gan Latvijā, gan pasaulē. Izvērtēta to atbilstība izveides principiem par modernu un ērtu sulu bāru. Diplomdarbs sastāv no 3 nodaļām, 14 apakšnodaļām un 5 pielikumiem. Tā apjoms ir 94 lappuses. Darbā izmantoti 44 informācijas avoti. Radošajā daļā tiek izstrādāts interjera projekts atbilstoši mūsdienu bāra nosacījumiem, balstoties uz…
Hyperosmolar therapy for acute brain injury: study protocol for an umbrella review of meta-analyses and an evidence mapping
2020
Introduction Acute brain injury is a challenging public health problem worldwide. Elevated intracranial pressure is a common complication after acute brain injury. Hyperosmolar therapy is one of the main therapeutic strategies for the management of intracranial hypertension. This study protocol outlines an umbrella review of meta-analyses which will investigate the benefits and harms of hyperosmolar therapy routinely used for the management of acute brain injury in the intensive care. Methods and analysis We will search PubMed/MEDLINE, EMBASE and the Cochrane Database of Systematic Reviews. We will include meta-analyses of primary research studies (eg, randomised controlled trials, observat…
Benefits of area-wide traffic calming measures: outcomes still to assess
2008
The role of traffic calming schemes in urban network management is mainly to minimize undesirable effect of traffic in residential areas; in this context accident reduction can be a realistic objective. Several studies, indeed, inform us that traffic calming is a major part of the treatments available to reduce road accidents in urban areas. Paradoxically the increase of the accident rate per kilometre travelled has been observed in the urban context as result of the wellknown accident migration phenomenon. In connection to these considerations, the effectiveness of traffic calming measures on road safety is discussed in this paper. Then, after a synthetic exposition of the conceptual formu…