Search results for " Direct"
showing 10 items of 943 documents
Perspectives for the Treatment of Brucellosis in the 21st Century: The Ioannina Recommendations
2007
Policy Forum. Competing interests: ER has received research grants from Daiichi, Bayer, and Theravance and has served as a consultant to Pfizer, Theravance, Bayer, Wyeth, Rosetta, and BiondVax. Summary Points Brucellosis remains the commonest anthropozoonosis worldwide, and its treatment remains complex, requiring protracted administration of more than one antibiotic. In November 2006, a consensus meeting aimed at reaching a common specialist statement on the treatment of brucellosis was held in Ioannina, Greece under the auspices of the International Society of Chemotherapy and the Institute of Continuing Medical Education of Ioannina. The author panel suggests that the optimal treatment o…
La alternancia de la oratio recta y de la oratio obliqua en los discursos intercalados de la historiografía romana
2009
Siguiendo la tradición griega, los historiadores romanos incluían en sus obras desarrollos oratorios de sus personajes, alternando la oratio recta, que reproducía de forma supuestamente literal las palabras de los protagonistas, y la oratio obliqua, caracterizada por la reubicación del discurso en relación a las coordinadas espacio-temporales de su propio enunciado. Este método de reproducción discursivo tuvo un desarrollo inusitado en la lengua latina por no necesitar un verbo introductor ante cada nuevo enunciado. Un repaso de la historiografía romana permite entrever las evidentes diferencias de uso entre las diversas épocas y los diferentes historiadores: algunos no incluyeron en sus ob…
Una primera aproximación a la información de referencia al sida
2002
La información científica y técnica es al mismo tiempo una parte esencial para la inves¬tigación así como un producto de esta actividad. El objetivo de este artículo es ofrecer información básica que nos dé a conocer cómo acceder a la información que necesitan los profesionales, estudiantes e interesados por la temática del SIDA. Siendo una de las enfermedades más extendidas y estudiadas, existe multitud de documentos que abor¬dan desde los últimos fármacos, hasta las últimas prácticas terapéuticas. El avance de la técnica ha ido parejo al avance en el estudio de dicha enfermedad, de manera que si necesitamos estar al corriente de lo último, debemos acceder a los bancos de datos, generales …
Genesi geometrica delle volte centriche
1996
Un'analisi completa degli organismi voltati comporta lo studio delle molteplici componenti necessarie alla loro definizione: configurazione geometrica, sistema costruttivo, area storico-geografica di appartenenza, interpretazioni Stilistiche. L’obiettivo di questo studio è indirizzato all' analisi delle volte continue su pianta centrica definibili attraverso le leggi della geometria euclidea. L’indagine si pone all'interno dei confini relativi alla loro configurazione geometrica e il criterio adottato, svincolato da classificazioni di carattere tipologico o stilistico, propone l'identificazione di famiglie geometriche in base alla figura del poligono di base dell'impianto. Si può identifica…
Efficacy of an internet-based psychological intervention for problem gambling and gambling disorder: study protocol for a randomized controlled trial
2021
Gambling Disorder is a prevalent non-substance use disorder, which contrasts with the low number of people requesting treatment. Information and Communication Technologies (ICT) could help to enhance the dissemination of evidence-based treatments and considerably reduce the costs. The current study seeks to assess the efficacy of an online psychological intervention for people suffering from gambling problems in Spain. The proposed study will be a two-arm, parallel-group, randomized controlled trial. A total of 134 participants (problem and pathological gamblers) will be randomly allocated to a waiting list control group (N = 67) or an intervention group (N = 67). The intervention program i…
Transcranial direct current stimulation preconditioning modulates the effect of high-frequency repetitive transcranial magnetic stimulation in the hu…
2012
Experimental studies emphasize the importance of homeostatic plasticity as a mean of stabilizing the properties of neural circuits. In the present work we combined two techniques able to produce short-term (5-Hz repetitive transcranial magnetic stimulation, rTMS) and long-term (transcranial direct current stimulation, tDCS) effects on corticospinal excitability to evaluate whether and how the effects of 5-Hz rTMS can be tuned by tDCS preconditioning. Twelve healthy subjects participated in the study. Brief trains of 5-Hz rTMS were applied to the primary motor cortex at an intensity of 120% of the resting motor threshold, with recording of the electromyograph traces evoked by each stimulus o…
Do Cross-Country Differences in Accounting Conservatism Explain Variations in the Degree of Investor Diversification?
2009
We show that the level of conditional accounting conservatism of foreign markets is significantly and positively associated with decisions to diversify portfolios internationally. This positive association could be either because conditional conservatism per se is attractive to international investors, or because the un-modelled factors that attract foreign investors to a country also cause these countries to adopt conditionally conservative accounting practices. However, if conditional conservatism serves to alleviate foreign investors’ concerns related to insiders having asymmetric access to information then one would also expect the chosen mode of entry into a foreign market (as foreign …
An approximation to the diachronic analysis of mitigation and face in dialogues between mother and child in the nineteenth and twentieth centuries
2018
Este artículo aborda la evolución del uso de la atenuación en los diálogos madre-hijo y sus efectos en la imagen sociocultural en los siglos XIX y XX. Para ello, utilizando como corpus cuatro obras de teatro de este periodo, se analiza cualitativa y cuantitativamente el empleo de la atenuación como estrategia pragmática en los actos directivos realizados en la proyección de estas relaciones. Los resultados de este estudio apuntan a que se ha producido una evolución desde la jerarquía hacia una progresiva solidaridad. This paper aims to analyse the evolution of the use of mitigation in dialogues between mother and child and their effects on sociocultural face in the nineteenth and twentieth …
Optimising management of patients with hepatitis C virus in the age of direct-acting antivirals: results of a Delphi consensus.
2018
OBJECTIVE: To optimize the management of patients with chronic hepatitis C virus (HCV). MATERIALS AND METHODS: We developed two questionnaires to determine Italian healthcare professionals’ opinions on the overall management of HCV chronic liver disease and the use of direct-acting antivirals (DAAs) in the treatment of HCV. A Delphi consensus method using the RAND/UCLA appropriateness method was used to determine opinions of an expert panel (EP) of specialists. RESULTS: Overall 443 physicians from 167 Italian centres completed the two questionnaires. The EP confirmed the importance of collaboration with general practitioners (GPs) and HCV testing in high-risk groups, but did not agree on tr…
New Modes of Regulation for Health and Safety: Post-Enlargement Policy Perspectives for the European Union
2006
The recent joining of ten new member states to the European Union, eight of which are former communist countries, has reopened inherent tensions in current European Union (EU) policy-making on safety and health in the workplace. These spring from seemingly incompatible objectives; the need to ensure broad EU member state compliance with regulation, around agreed minimum standards through active regulatory enforcement, and the promotion of “softer” voluntary initiatives in the management of workplace risks and hazards in order to create “a culture of prevention.” The present EU strategy which ends in 2006, seeks to secure a balance between both sets of objectives. However, with respect to t…