Search results for " END"

Changes in motor unit characteristics after eccentric elbow flexor exercise

2010

Morphological evidence suggests that fast-twitch fibers are prone to disruption of their membrane structures by eccentric exercise. However, it is unclear how this is reflected in the discharge rate and action potential propagation of individual motor units, especially at high contraction levels. High-density surface electromyograms were recorded from biceps brachii muscle and decomposed to individual motor unit action potentials at isometric contraction levels between 10% and 75% of maximal voluntary contraction (MVC) before intermittent maximal elbow flexor eccentric exercise, and two hours (2H), two days (2D) and four days (4D) post-exercise. Maximal voluntary force decreased by 21.3±5.6…

Osmolality of various viscoelastic substances: comparative study.

2000

Abstract Purpose To determine the osmolality of various viscoelastic substances. Setting Department of Ophthalmology, Johannes Gutenberg-University, Mainz, and Institute for Medical Device Testing, Memmingen, Germany. Methods The analysis was carried out according to the European Pharmacopoeia by means of a calibrated osmometer using the freezing-point depression method. Each syringe was analyzed as a duplicate analysis. Results Mean osmolalities (mOsmol/kg) of the sodium hyaluronate viscoelastic substances were Allervisc® 299; Allervisc® Plus 307; Amvisc® Plus 335; AMO Vitrax® 284; Biolon® 279; Dispasan® 311; Dispasan® Plus 314; Healon® 295; Healon GV® 312; Healon®5 322; HYA-Ophtal® 376; M…

Iris Claw Phakic Lens—Intermediate and Long-term Corneal Endothelial Changes

1994

OBJECTIVE: To study the alterations in the corneal endothelial layer two years after the implantation of iris claw phakic lenses. STUDY DESIGN: Prospective study of postoperative results with a minimum follow-up of 6 months, maximum of two years and a mean of 14 months. SETTING: Department of Ophthalmology, ‘La Fe’ University Hospital, Department of Surgery of Valencia School of Medicine, Valencia, Spain. PATIENTS: Ninety eyes of 70 patients presenting high myopia who underwent anterior chamber phakic lens implantation with iris fixation IOLs in the last two years. MAIN OUTCOME MEASURES: Non-contact specular microscopy with video image system was used to perform examination of the corneal e…

Diabetes and the COVID-19 Pandemic: How Insights from Recent Experience Might Guide Future Management

2020

Type 2 Diabetes Mellitus and COVID-19: A Narrative Review

2021

The pandemic of coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has involved more than one hundred million individuals, including more than two million deaths. Diabetes represents one of the most prevalent chronic conditions worldwide and significantly increases the risk of hospitalization and death in COVID-19 patients. In this review, we discuss the prevalence, the pathophysiological mechanisms, and the outcomes of COVID-19 infection in people with diabetes. We propose a rationale for using drugs prescribed in patients with diabetes and some pragmatic clinical recommendations to deal with COVID-19 in this kind of patient.

Size and subclasses of low-density lipoproteins in patients with obstructive sleep apnea.

2012

Patients with obstructive sleep apnea (OSA) have proatherogenic dyslipidemia. We analyzed predictors of low-density lipoproteins' (LDLs) size in patients with OSA. In a cross-sectional study including 58 participants with OSA (30 without the metabolic syndrome [MetS] and 28 with MetS), we evaluated the size of LDL by gradient gel electrophoresis. Compared with patients without the MetS, those with MetS showed lower LDL size ( P = .007), due to a reduction in large LDL-I particles ( P = .002) and an increase in small, dense LDL-IIIA ( P = .048) and LDL-IIIB ( P = .037). The size of LDL correlated inversely with age ( r = −.268, P = .042) and serum triglycerides ( r = −.364, P = .005), and p…

Associations between parenting and substance use, meal pattern and food choices: A cross-sectional survey of 13,269 Norwegian adolescents

2019

Identifying factors that affect adolescent lifestyle behaviors is essential in order to develop effective generic prevention approaches. This study aimed to investigate the association between parental monitoring, parental emotional support, parental-adolescent conflict and adolescent substance use, meal pattern and food choices. The study included data from 13,269 Norwegian adolescents aged 13–16 years collected in 2016. Multivariable logistic regression models adjusted for gender, age and parental education were applied. Results show that low parental monitoring was associated with increased substance use (Odds ratios (OR) ranging from 2.8; 95% Confidence intervals (CI) 2.1–3.6 to OR 3.8;…

Evaluation of the UP4FUN Intervention: A Cluster Randomized Trial to Reduce and Break Up Sitting Time in European 10-12-Year-Old Children

2015

Background The UP4FUN intervention is a family-involved school-based intervention aiming at reducing and breaking up sitting time at home (with special emphasis on screen time), and breaking up sitting time in school among 10–12 year olds in Europe. The purpose of the present paper was to evaluate its short term effects. Methodology/Principal Findings A total of 3147 pupils from Belgium, Germany, Greece, Hungary and Norway participated in a school-randomized controlled trial. The intervention included 1–2 school lessons per week for a period of six weeks, along with assignments for the children and their parents. Screen time and breaking up sitting time were registered by self-report and to…

Differences in cyclic fatigue lifespan between two different heat treated NiTi endodontic rotary instruments: WaveOne Gold vs EdgeOne Fire

2019

Background Aim of this study is to investigate the cyclic fatigue resistance of the Gold treated WaveOne Gold and the Firewire treated EdgeOne Fire instruments. The null hypotesis was that there were no differences between the lifespan of Gold treated and FireWire treated instruments when subjected to cyclic fatigue tests. Material and Methods 40 new NiTi instruments with a length of 25 mm were tested: 20 Wave One Gold Medium (WOG), tip size 35 and variable taper (Dentsply Maillefer, Ballaigues, Switzerland) and 20 Edge One Fire (EOF) (EdgeEndo, Albuquerque, New Mexico) tip size 35 and the same variable taper. A mobile support for the electric handpiece and a stainless-steel block containin…

Characteristics of patients with type 2 diabetes mellitus newly treated with GLP-1 receptor agonists (CHADIG Study): a cross-sectional multicentre st…

2016

Ajuda rebuda: GlaxoSmithKline Several glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1Ra) have been made recently available in Spain for type 2 diabetes mellitus (DM2) treatment. There are no published data on the clinical and sociodemographic profile of patients initiating treatment with GLP-1Ra in Spain. Our objective was to understand these patients' characteristics in a real-world clinical practice setting. Design. Cross-sectional observational study. Setting. Spanish specialist outpatient clinics.Participants 403 adults with DM2 initiating GLP-1Ra treatment were included. Primary and secondary outcome measures Sociodemographic and DM2-related clinical data, including treatment …