Search results for " END"
showing 10 items of 4885 documents
Extended characterization of human umbilical cord matrix mesenchymal stem cells: expression of novel markers, immunoregulatory molecules, and differe…
2009
Anthropometric indices, lipid profile, and lipopolysaccharide-binding protein levels in metabolic endotoxemia: A case-control study in Calabar Metrop…
2020
Objectives: To determine the anthropometric indices, lipopolysaccharide-binding proteins (LBP), and lipid profile in patients with metabolic endotoxemia. Methods: The study comprised of 47 patients with metabolic endotoxemia (the metabolic endotoxemia group) and 43 controls (the control group). Patients in the metabolic endotoxemia group were categorized further into three subgroups including the normal weight group (n=8), the overweight group (n=12) and the obese group (n=27). Height, weight, waist, and hip circumference were measured, and waist-hip ratio (WHR) and body mass index (BMI) were calculated. LBP was determined by ELISA and total cholesterol, triglycerides, high density lipoprot…
Endocrine and pro-inflammatory activity of visceral (VAT) and subcutaneous (SAT) adipose tissue in morbidly obese patients with and without metabolic…
2011
Reduce cardiovascular risk through close follow up of the metabolic syndrome during menopause in women: a possible goal
2009
After a treatment period a significant reduction of BMI. HDL-cholesterol, tryglicerides, diastolic blood pressure and fasting blood glucose, in menopausal women with metabolic syndrome, were performed, as well as a significant reduction of score of relative cardiovascular risk
The E3 Ubiquitin Ligase MID1 Catalyzes Ubiquitination and Cleavage of Fu
2014
Sonic Hedgehog (SHH)-GLI signalling plays an important role during embryogenesis and in tumorigenesis. The survival and growth of several types of cancer depend on autonomously activated SHH-GLI signalling. A protein complex containing the ubiquitin-ligase MID1 and protein phosphatase 2A (PP2A) regulates the nuclear localization and transcriptional activity of GLI3, a transcriptional effector molecule of SHH, in cancer cell lines with autonomously activated SHH signalling. However, the exact molecular mechanisms that mediate the interaction between MID1 and GLI3 remained unknown. Here, we show that MID1 catalyses the ubiquitination and proteasomal cleavage of the GLI3-regulator Fu. Our data…
The seed endophytic microbiota of Citrus limon L. Burm. F
2017
Background Plant seeds possess a complex microbiota which may play a crucial rolein a plethora of mechanisms, such as preservation, germination, seedling development, plant growth and health. In particular, seed endophytic microbiota is gaining more and more consideration due to the fact that it may be vertically transmitted to ensure individual competitive advantages. The Citrusspecies, including C.limon,areone of the most economically important evergreen fruit crops in the world. Objectives i)Identification and characterization ofmicrobial isolates from Citrus limon L. Burm. F. seed endosphere. ii) Structure of Citrus limon L. Burm. F. seed endosphytic microbiota. Methods -Surface-sterili…
Infective Endocarditis: Preliminary Results of a Cohort Study in the Southern Italian Population.
2020
Background Infective endocarditis (IE) is an uncommon disease with an involved interplay of clinical and surgical team management. We aimed to define diagnosis parameters and delineate in-hospital management in patients with IE admitted in a tertiary hospital of Southern Italian. Materials and methods Fifty-six consecutive patients (42 males, 14 females; age range: 34-85 years) admitted for IE in the Infectious Diseases, Cardiac Surgery, and Cardiology units, between January 2011 and August 2017, were enrolled. Demographic data, mortality, comorbidities, specimen type, microscopy results, special histological staining performed, and antimicrobial therapy were collected and analyzed. Any com…
Estudio de la acción proinflamatoria de Angiotensina II y su posible modulación. Papel de Angiotensina II en disfunciones endoteliales.
2002
La acumulación leucocitaria es una característica de los primeros estadios de la lesión aterosclerótica, de infarto agudo de miocardio y de enfermedades renales de diversa etiología. Receptores para Angiotensina-II (Ang-II) han sido hallados en monocitos y Ang-II puede promover la activación y adhesión de estas células. Este proceso podría desencadenar o perpetuar el daño endotelial asociado a aterosclerosis e hipertensión. Los resultados de nuestro estudio demuestran que Ang-II, a dosis subvasoconstrictoras y fisiológicas, presenta propiedades proinflamatorias in vivo a nivel agudo; en concreto, produce acumulación leucocitaria en vénulas de la microcirculación mesentérica de la rata a tra…
Ikääntyvät ja työhyvinvointi : 45-64-vuotiaiden työssäjaksamiskokemuksia
2017
The aim of this study was to offer an additional point of view of the age political discourse on work endurance, initiated by Finland’s public administration in the early 2000s. The personal experiences of the staff of a multi-professional work community were exploited to find clues to occupational well-being and endurance at work. Seventeen employees aged 45—64 at the actual work community were chosen as data or material for study, i.e. to be interviewed. A phenomenological-hermeneutical approach was applied to shed light on how to create well-being at work. Personal experiences of work endurance were analyzed and interpreted along the guidelines of the stepwise method used in phenomenolog…
Applying Minimalism in the Real World: Results From a Workshop
2020
Minimalism is a user-centered, contextual and goal-oriented approach to technical communication originally developed by John M. Carroll (1990). In minimalism, the aim is to produce user documentation that focuses on the user’s needs, helps the user recover from error situations, and strengthens the user’s skills in working with the system (Carroll & van der Meij 1995: 245). The challenge with minimalism has been its practical application: although user-centeredness – the core of minimalism – is the key issue in technical communication, the abstract nature of the approach and its focus on software documentation has made it difficult to apply in industry settings (Virtaluoto, Suojanen & Isohe…