Search results for " ENHANCEMENT"
showing 10 items of 521 documents
Gene therapy and editing in the treatment of hereditary blood disorders: Medical and ethical aspects
2021
Gene therapy and gene editing are revolutionising the treatment of genetic diseases, most notably haematological disorders. This paper evaluates the use of both techniques in hereditary blood disorders. Many studies have been conducted in this field, especially with gene therapy, with very promising results in diseases such as haemophilia, certain haemoglobinopathies and Fanconi anaemia. The application of these techniques in clinical practice and the foreseeable development of these approaches in the coming years suggest that it might be useful to evaluate the results achieved thus far. It is also essential to reflect on the possible bioethical concerns raised by the use of both technique…
Engineering light emission of two-dimensional materials in both the weak and strong coupling regimes
2017
Abstract Two-dimensional (2D) materials have promising applications in optoelectronics, photonics, and quantum technologies. However, their intrinsically low light absorption limits their performance, and potential devices must be accurately engineered for optimal operation. Here, we apply a transfer matrix-based source-term method to optimize light absorption and emission in 2D materials and related devices in weak and strong coupling regimes. The implemented analytical model accurately accounts for experimental results reported for representative 2D materials such as graphene and MoS2. The model has been extended to propose structures to optimize light emission by exciton recombination in…
Il progetto I-Access. Patrimonio culturale e accessibilità
2021
The volume is one of 3 (see notes) containing the results of the I-Access project: implementing accessibility in urban historic center's use and knowledge (Interreg V-A Italy-Malta, axis I, notice 1/16), of which R.P. is the project leader. Each section - accessibility, digital innovation, interventions, community - has always been referred, by scientific coordination, to cultural heritage. in the Appendices the fact sheets and verification of accessibility and the projects for overcoming the architectural barriers carried out, relating to the two churches of S. Maria la Nova and S. Maria in Valverde, are represented. for all activities, please refer to the site www.i-access.eu
Information processing in nuclear magnetic resonance imaging.
1988
An extended image analysis and classification system is presented to discuss the principal composition of the components as well as the methods of its realization in the field of reference based NMR diagnostics and tissue characterization.
Superresolution digital holographic microscopy for three-dimensional samples.
2009
An approach that allows superresolution imaging of three-dimensional (3-D) samples by numerical refocusing is presented in the field of digital holographic microscopy. Based on the object's spectrum shift produced by tilted illumination, we present a time multiplexing superresolved approach to overcome the Abbe's diffraction limit. The proposed approach uses a microscope in a Mach-Zehnder interferometric architecture with the particularity that the output plane does not coincide with the image plane. Thus, a set of off-axis non-image plane holograms are sequentially recorded for every tilted beam used in the illumination stage. After that and by using simple digital post-processing and nume…
Filter performance parameters for vectorial high-aperture wave fields.
2008
Performance parameters have been presented that can be used to compare the focusing performance of different optical systems, including the effect of pupil filters. These were originally given for the paraxial case and recently extended to the high-aperture scalar regime. We generalize these parameters to the full vectorial case for an aplanatic optical system illuminated by a plane-polarized wave. The behavior of different optical systems is compared.
Measurement of thee+e−→ηJ/ψcross section and search fore+e−→π0J/ψat center-of-mass energies between 3.810 and 4.600 GeV
2015
Using data samples collected with the BESIII detector operating at the BEPCII collider at 17 center-of-mass energies from 3.810 to 4.600 GeV, we perform a study of e(+)e(-) -> eta J/psi and pi(0)J/psi The Born cross sections of these two processes are measured at each center-of-mass energy. The measured energy-dependent Born cross section for e(+)e(-) -> eta J/psi shows an enhancement around 4.2 GeV. The measurement is compatible with an earlier measurement by Belle.
Carbon coatings for soft-x-ray reflectivity enhancement
2007
In X-ray astronomical telescopes, the focalization of the radiation is achieved by means of grazing incidence Wolter I (parabola + hyperbola) optics in total reflection regime. In general, high density materials (e.g. Au, Pt, Ir, W) are used as reflecting coatings, in order to increase as much as possible the cut-off angles and energies for total reflection. However these materials present an important reduction of the reflectivity between 0.2 and 5 keV, due to the photoabsorption, and this phenomenon is particularly enhanced in correspondence of the M absorption edges (between 2 and 3.5 keV). In general, this determines a strong decrease of the telescope effective area. To overcome the pro…
Subsecond fluorine-19 MRI of the lung
2006
Minimal scan times in rapid fluorine-19 MRI using sulfur hexafluoride (SF6) have been on the order of 10 s. Because of the very short T1 relaxation time of SF6 (T1 = 1.65 ms), high receiver bandwidths are necessary to allow for a high number of excitations. Since high bandwidths cause high levels of electronic noise, SNR per acquisition has been too low to further reduce scan time. The purpose of this study was to investigate whether scan times could be reduced using hexafluoroethane (C2F6), a gas with a longer T1 (T1 = 7.9 ms) at a relatively low bandwidth of 488 Hz/pixel. Gradient-echo images were acquired during and after completion of the wash-in of a 70% C2F6- 30% O2 mixture. Peak SNR …
Influence of pixel size on quantification of airway wall thickness in computed tomography.
2009
Objectives: The purpose of this study was to determine the point where a further decrease in voxel size does not result in better automatic quantification of the bronchial wall thickness by using 2 different assessment techniques. Materials and Methods: The results from the commonly used full-width-at-half-maximum (FWHM) principle and a new technique (integral-based method [IBM]) were compared for thin-section multidetector computed tomography (MDCT) data sets from an airway phantom containing 10 different tubular airway phantoms and in a human subsegmental bronchus in vivo. Correlation with the actual wall thickness and comparison of the wall thicknesses assessed for different voxel sizes …