Search results for " ENHANCEMENT"

Dalla didattica al progetto di restauro: la collaborazione fra istituzioni per conoscere, conservare, valorizzare e fruire il patrimonio storico arch…

2020

La volontà di rendere sempre più incisivo e professionalizzante l’insegnamento del Restauro nei corsi di laurea in Architettura ha mosso chi scrive alla volontà di stabilire, tramite una convenzione, un rapporto stabile con la Soprintendenza per i Beni Culturali e Ambientali di Palermo, città in cui si opera, da attuare con i corsi di Laboratorio di Restauro dei Monumenti nel Corso di Laurea LM-4 in Architettura di Palermo o nella redazione di tesi di laurea. Attraverso l’esame dei due primi casi trattati congiuntamente (monastero di S. Caterina d’Alessandria, caserma dei Carabinieri Carlo Alberto Dalla Chiesa, nel complesso di S. Giacomo dei Militari) si delineano le opportunità e le criti…

New centrality in UNESCO buffer-zones: two Mediterranean case studies. Per una nuova centralità delle buffer-zones UNESCO: due casi studio nel Medite…

2022

The paper presents an interdisciplinary reflection on the potential for sustainable development of communities and their cultural landscapes expressed by UNESCO Buffer Zones in the Mediterranean, with the intention of transforming their widespread perception as mere tools of protection and urban planning into concrete integrated proposals for protection and enhancement, and also taking into account the role of museums in promoting the understanding of cultural heritage and the maturation of an awareness of the value of such actions. With reference to the 2004 guidelines UNESCO and starting from the evaluation of some management plans, such as that of the Arab-Norman itinerary in Palermo and…

Intravenous Contrast Material for Cardiac Computed Tomography

2023

Purpose: The Italian Registry of Contrast Material use in Cardiac Computed Tomography (iRCM-CCT) is a multicenter, multivendor, observational study on the use of contrast media (CM) in patients undergoing cardiac computed tomography (CCT). The aim of iRCM-CCT is to assess image quality and safety profile of intravenous CM compounds. Materials and methods: iRCM-CCT enrolled 1842 consecutive patients undergoing CCT (≥50 per site) at 20 cluster sites with the indication of suspected coronary artery disease. Demographic characteristics, CCT, and CM protocols, clinical indications, safety markers, radiation dose reports, qualitative (ie, poor vascular enhancement) and quantitative (ie, HU attenu…

. Strategie e iniziative per il recupero e la valorizzazione: un bilancio sui centri storici siciliani

2020

The present contribution focuses on the strategies carried out to hinder depopulation and facilitate the recovery of the historical city centres in Sicily in the last fifty years. In particular, the essay analyses if the strategies and initiatives fostered in this field had been respectful of the physical characteristics of these small towns. Furthermore, the present study intends to assess if the improvement of the “quality of life” has been considered among the strategies carried out to contrast depopulation. The scarce efficacy of policies and strategies over the last fifty years, which emerges from this analysis, is partially due to the endemic inability of politicians and local communi…

Enhancing system level performance of third generation cellular networks through VoIP and MBMS services

2010

Monografie di Agathòn. Atti del Symposium East-West Artistic and Technological Contaminations/Oriente-Occidente. Contaminazioni Artistiche e Tecnolog…

2013

AgAthón, the Ph.D.’s journal collecting together the best of the works about the renovation and the enhancement of ancient contexts, has had increasing success among institutions and both Italian and foreign researchers. The choral pattern chosen in the four sectors, which alludes to the Greek city, has certainly contributed to create this appreciation: the Agorá, like the central space in the pólis, for guest contributions; the Stoá, the covered portico under which the philosopher Zeno used to teach his disciples, for the Ph.D. teachers’ contributions; the gymnásion, the place of endeavour for young Greeks training their bodies and minds, is the section meant for the doctoral candidates; l…

Measurement of dielectron production in central Pb-Pb collisions at √sNN = 2.76 TeV

2019

Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI. The first measurement of dielectron (e + e −) production in central (0 – 10 %) Pb – Pb collisions at √sNN=2.76TeV at the LHC is presented. The dielectron invariant-mass spectrum is compared to the expected contributions from hadron decays in the invariant-mass range 0 < mee < 3.5 GeV / c2. The ratio of data and the cocktail of hadronic contributions without vacuum ρ0 is measured in the invariant-mass range 0.15 < mee < 0.7 GeV / c2, w…

The Nasal Epithelium as a Factory for Systemic Protein Delivery

2002

We have previously shown that recombinant Sendai virus (SeV) produces efficient in vivo airway epithelial gene transfer. The ability to produce therapeutic levels of circulating proteins following noninvasive gene transfer would have widespread clinical application. Here, we compared nose, lung, and skeletal muscle for the ability to produce circulating levels of the secreted mouse antiinflammatory cytokine interleukin-10 (IL10) following SeV-mediated gene transfer. High levels of serum IL10 were obtained from each site with a potency order of lung > nose > muscle for a given viral titer. Serum levels from each site were within the likely required range for anti-inflammatory effects. The co…

Genomic structure and promoter analysis of pathogen-inducedrepatgenes fromSpodoptera exigua

2009

The repat gene family encodes midgut proteins overexpressed in response to pathogen infection in the lepidopteran Spodoptera exigua. Up-regulation of repat genes has been observed after challenging the larvae with both Bacillus thuringiensis toxins and after infection with the baculovirus Autographa californica multiple nucleopolyhedrovirus. In our study, PCR amplification of the genomic region and genome walking were used to obtain the genomic structure and the sequence of the 5'-upstream region of repat1 and repat2, two of the most phylogenetically distant members of the repat family. A similar gene structure between repat1 and repat2 has been found, with conserved exon-intron positions a…

PTC124-mediated translational readthrough of a nonsense mutation causing Usher syndrome type 1C.

2011

We investigated the therapeutic potential of the premature termination codon (PTC) readthrough-inducing drug PTC124 in treating the retinal phenotype of Usher syndrome, caused by a nonsense mutation in the USH1C gene. Applications in cell culture, organotypic retina cultures, and mice in vivo revealed significant readthrough and the recovery of protein function. In comparison with other readthrough drugs, namely the clinically approved readthrough-inducing aminoglycoside gentamicin, PTC124 exhibits significant better retinal biocompatibility. Its high readthrough efficiency in combination with excellent biocompatibility makes PTC124 a promising therapeutic agent for PTCs in USH1C, as well a…