Search results for " EPIDEMIOLOGY"

showing 10 items of 704 documents

Correction to: Atypical pathogens in hospitalized patients with community-acquired pneumonia: a worldwide perspective (BMC Infectious Diseases, (2018…

2020

Following publication of the original article [1], the authors identified that they have been incorrectly tagged under the name of their related consortium GLIMP Study Group.

CAP Atypical pathogens EpidemiologySettore MED/10 - Malattie Dell'Apparato Respiratorio
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The three facets of the SARS-CoV-2 pandemic during the first two waves in the northern, central, and southern Italy

2023

Background: There is a scarcity of information in literature regarding the clinical differences and comorbidities of patients affected by Coronavirus disease 2019 (COVID-19), which could clarify the different prevalence of the outcomes (composite and only death) between several Italian regions. Objective: This study aimed to assess the heterogeneity of clinical features of patients with COVID-19 upon hospital admission and disease outcomes in the northern, central, and southern Italian regions. Methods: An observational cohort multicenter retrospective study including 1210 patients who were admitted for COVID-19 in Infectious diseases, Pulmonology, Endocrinology, Geriatrics and Internal Med…

COVID-19 Epidemiology Italy Mortality Public health SARS-CoV-2Infectious DiseasesSettore MED/09 - Medicina InternaPublic Health Environmental and Occupational HealthGeneral MedicineSettore MED/49 - Scienze Tecniche Dietetiche ApplicateSettore MED/13 - Endocrinologia
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Distribution of three different isolates of Citrus Tristeza Virus in southern Italy

2010

CTV epidemiologySettore AGR/12 - Patologia Vegetale
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Epidemiological, clinical and molecular characterization of Lynch‐like syndrome: A population‐based study

2019

Colorectal carcinomas that are mismatch repair (MMR)‐deficient in the absence of MLH1 promoter methylation or germline mutations represent Lynch‐like syndrome (LLS). Double somatic events inactivating MMR genes are involved in the etiology of LLS tumors. Our purpose was to define the clinical and broader molecular hallmarks of LLS tumors and the population incidence of LLS, which remain poorly characterized. We investigated 762 consecutive colorectal carcinomas operated in Central Finland in 2000–2010. LLS cases were identified by a stepwise protocol based on MMR protein expression, MLH1 methylation and MMR gene mutation status. LLS tumors were profiled for CpG Island Methylator Phenotype (…

Cancer ResearchMICROSATELLITE INSTABILITYDNA mismatch repairMISMATCH-REPAIR DEFICIENCYGene mutationmedicine.disease_cause0302 clinical medicinelynch syndromeFinlandMolecular Epidemiologyeducation.field_of_studyMutationISLAND METHYLATOR PHENOTYPENONPOLYPOSIS COLORECTAL-CANCERlynch-like syndromeTUMORSLynch syndrome3. Good healthOncology030220 oncology & carcinogenesissyöpätauditColorectal NeoplasmsMutL Protein Homolog 1Lynch-like syndromeAdult3122 CancersPopulationsuolistosyövätCpG island methylator phenotypeBiologyta3111FREQUENCYMLH103 medical and health sciencesGermline mutationcolorectal carcinomaBRAF MUTATIONCOLONmedicineHumansLynchin oireyhtymäeducationneoplasmsMSIAgedRetrospective StudiesCpG Island Methylator PhenotypeMicrosatellite instabilityDNASOMATIC MUTATIONSta3122CpG Island Methylator phenotypemedicine.diseaseColorectal Neoplasms Hereditary Nonpolyposisdigestive system diseasesCOPY NUMBERMutationCancer researchInternational Journal of Cancer
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Registration of childhood cancer: Moving towards pan-European coverage?

2015

Cancer is relatively rare in childhood, but it contributes considerably to childhood mortality, years of life lost per person and late effects in survivors. Large populations need to be covered to set up meaningful studies of these rare conditions. Cancer registries ensure cancer surveillance, thus providing the basis for research as well as policy decisions. In this paper we examine coverage of childhood population by cancer registries in Europe and encourage national cancer registration. Over 200 cancer registries in various stages of development were identified as collecting data on childhood cancer patients in Europe. They cover 52% of the childhood population in the World Health Organi…

Cancer ResearchPediatricsmedicine.medical_specialtyAdolescentChildhood cancerPopulation610 Medicine & healthWorld Health OrganizationNeoplasmsEnvironmental healthHumansMedicinemedia_common.cataloged_instance1306 Cancer ResearchEuropean UnionRegistriesAge of OnsetEuropean unionChildeducationmedia_commoneducation.field_of_studyData collectionbusiness.industryIncidence (epidemiology)Infant NewbornInfantCancer10060 Epidemiology Biostatistics and Prevention Institute (EBPI)medicine.diseaseEuropeYears of potential life lostOncologyChild PreschoolData qualityPractice Guidelines as Topic2730 OncologybusinessEuropean Journal of Cancer
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O78. Which phenotype adds to cardiovascular risk assessment? Lessons from the Gutenberg heart study: A prospective, population-based cohort study in …

2008

Cancer ResearchPediatricsmedicine.medical_specialtyPhysiologybusiness.industryClinical BiochemistryRetrospective cohort studyBiochemistryPhenotypePopulation based cohortCardiovascular epidemiologymedicineRisk assessmentbusinessNitric Oxide
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Candida bloodstream infections in intensive care units: Analysis of the extended prevalence of infection in intensive care unit study

2011

Objectives: To provide a global, up-to-date picture of the prevalence, treatment, and outcomes of Candida bloodstream infections in intensive care unit patients and compare Candida with bacterial bloodstream infection. Design: A retrospective analysis of the Extended Prevalence of Infection in the ICU Study (EPIC II). Demographic, physiological, infection-related and therapeutic data were collected. Patients were grouped as having Candida, Gram-positive, Gram-negative, and combined Candida/bacterial bloodstream infection. Outcome data were assessed at intensive care unit and hospital discharge. Setting: EPIC II included 1265 intensive care units in 76 countries. Patients: Patients in partic…

Candida albicanMaleAntifungal AgentsIron metabolism Pathogenesis and modulation of inflammation [IGMD 7]Settore MED/41 - AnestesiologiaCritical Care and Intensive Care Medicinelaw.inventionEchinocandinschemistry.chemical_compound0302 clinical medicineRetrospective StudieCaspofunginlawCandida albicansPrevalenceAntifungal Agent030212 general & internal medicineCandida albicansFluconazoleMESH: SepsisFungemiaintensive careMedicine(all)MESH: AgedCross Infection0303 health scienceseducation.field_of_studyMESH: Middle AgedfungemiabiologyCandidiasisMiddle AgedIntensive care unitMESH: Candidiasisbacteremia; epidemiology; fungemia; intensive care; outcome assessment (health care); Aged; Antifungal Agents; Candida albicans; Candidiasis; Cross Infection; Echinocandins; Female; Fluconazole; Humans; Intensive Care Units; Lipopeptides; Male; Middle Aged; Prevalence; Retrospective Studies; Sepsis; Critical Care and Intensive Care Medicine3. Good healthIntensive Care Unitsbacteremia epidemiology fungemia intensive care outcome assessment (health care)CandidiasiMESH: FluconazoleepidemiologyFemaleHumanmedicine.drugmedicine.medical_specialtySepsiIntensive Care UnitPopulationLipopeptides03 medical and health sciencesSepsisIntensive caremedicineHumansEchinocandinbacteremiaIntensive care medicineeducationMESH: PrevalenceAgedRetrospective Studiesoutcome assessment (health care)MESH: Humans030306 microbiologybusiness.industryMESH: Candida albicansMESH: EchinocandinsMESH: Cross InfectionMESH: Retrospective Studies[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and GastroenterologyMESH: Antifungal Agentsmedicine.diseasebiology.organism_classificationMESH: MalechemistryBacteremiaMESH: Intensive Care UnitsCaspofunginbusinessMESH: FemaleFluconazole
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Relationships between diuretic related hyperuricemia and cardiovascular events: data from the URRAH (URic acid Right for heArt Health) study.

2021

Objective Although the relationship between hyperuricemia and cardiovascular events has been extensively examined, data on the role of diuretic-related hyperuricemia are still scanty. The present study was designed to collect information on the relationship between diuretic-related hyperuricemia and cardiovascular events. Methods The URic acid Right for heArt Health (URRAH) study is a nationwide, multicentre, observational cohort study involving data on individuals recruited from all the Italy territory under the patronage of the Italian Society of Hypertension with an average follow-up period of 122.3 ± 66.9 months. Patients were classified into four groups according to the diuretic use (y…

Cardiovascular eventMalemedicine.medical_specialtySettore MED/09 - Medicina InternaPhysiologymedicine.medical_treatmentdiureticRenal functionHyperuricemiaCardiovascular eventcardiovascular events; cardiovascular mortality; diuretic; uric acid030204 cardiovascular system & hematology03 medical and health scienceschemistry.chemical_compoundcardiovascular events0302 clinical medicineuric acidRisk Factorscardiovascular mortalityInternal medicineInternal MedicinemedicineHumans030212 general & internal medicineHyperuricemiaDiureticsHeart healthUric acid cardiovascular events diuretics epidemiologycardiovascular events cardiovascular mortality diuretic uric acidbusiness.industrySerum uric acidMiddle Agedmedicine.diseasechemistryHypertensionUric acidDiureticCardiology and Cardiovascular MedicinebusinessCohort study
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DMFT indekss un kariesa izplatība Latvijas Universitātes studentu zobārstniecības klīnikas pacientiem

2022

Mutes veselībai ir ļoti nozīmīgs iedzīvotāju labklājības faktors. Slikta mutes dobuma veselība var būt par iemeslu sāpēm, zobu zaudējumam, funkciju zudumumam un pazeminātai pašcieņai. Zobu kariess ir viena no divām visbiežāk sastopamajām mutes dobuma saslimšanām un zobu zaudējuma iemesliem. Epidemioloģiskie pētījumi, izmantojot dažādus starptautiski pieņemtus indeksus, lēš, ka globāli neārstēts kariess pastāvīgo zobos ir 2,3 miljardiem cilvēku un neārstēts kariess piena zobos - 532 miljoniem bērnu. Taču pētījumu pieaugušajiem ir daudz mazāk nekā bērniem, kas arī pamato darba mērķi - analizēt DMFT indeksu un kariesa izplatību pieaugušiem pacientiem, kuri apmeklē Latvijas Universitātes Studen…

Caries Prevalence in AdultsDMFT IndexDental Caries EpidemiologyCaries EtiologyMedicīna
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Chagas Disease Vector Control in a Hyperendemic Setting: The First 11 Years of Intervention in Cochabamba, Bolivia

2014

Background Chagas disease has historically been hyperendemic in the Bolivian Department of Cochabamba. In the early 2000s, an extensive vector control program was implemented; 1.34 million dwelling inspections were conducted to ascertain infestation (2000–2001/2003–2011), with blanket insecticide spraying in 2003–2005 and subsequent survey-spraying cycles targeting residual infestation foci. Here, we assess the effects of this program on dwelling infestation rates (DIRs). Methodology/Principal Findings Program records were used to calculate annual, municipality-level aggregate DIRs (39 municipalities); very high values in 2000–2001 (median: 0.77–0.69) dropped to ∼0.03 from 2004 on. A linear…

Chagas diseaseDisease EcologyBolivialcsh:Arctic medicine. Tropical medicineEndemic Diseaseslcsh:RC955-962EpidemiologyEctoparasitic Infestationsmedicine.disease_causeInsect ControlInfectious Disease EpidemiologyOddsInfestationTriatoma infestansparasitic diseasesmedicineMedicine and Health SciencesParasitic DiseasesAnimalsHumansChagas DiseasePublic and Occupational HealthTriatomaEctoparasitic infestationProtozoan InfectionsbiologyEcologylcsh:Public aspects of medicinePublic Health Environmental and Occupational Healthlcsh:RA1-1270Odds ratiomedicine.diseasebiology.organism_classificationTropical DiseasesConfidence intervalInfectious DiseasesTriatomaEpidemiological MonitoringDemographyResearch ArticleNeglected Tropical DiseasesPLoS Neglected Tropical Diseases
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