Search results for " Elderly patients"

showing 2 items of 22 documents

Eight-point compass rose underlay technique in 72 consecutive elderly patients with large incisional hernia

2011

Summary Background Repair of incisional hernia (IH) in the elderly is a challenge for the surgeon. Primary closure is preferable but is not always possible because of high recurrence rates of IH repaired without a prosthesis and/or possible respiratory and cardiovascular complications due to extreme tension of the margins. We report our experience with underlay mesh placement in elderly patients with large IH. Methods A total of 72 patients from January 2003 to December 2009 underwent IH repair involving placement of an intraperitoneal Gore® DualMesh® prosthesis. The prosthesis was first anchored at eight points in a compass rose pattern using a Gore® suture passer and then firmly secured t…

medicine.medical_specialtyIncisional herniamedicine.medical_treatmentHigh-risk elderly patientAdhesion (medicine)lcsh:GeriatricsProsthesisePTFE meshTension-free techniqueAbdominal wallLarge ventral herniaSuture (anatomy)PneumoperitoneumePTFE mesh; High-risk elderly patients; Large ventral hernia; Suture passer; Tension-free techniquemedicineLaparoscopyhigh-risk elderly patientsSuture passermedicine.diagnostic_testbusiness.industrymedicine.diseaseSurgeryDissectionlcsh:RC952-954.6Settore MED/18 - Chirurgia Generalemedicine.anatomical_structureGeriatrics and Gerontologybusiness
researchProduct

Safety and potential interaction of immunosuppressive drugs for the treatment of inflammatory bowel disease in elderly patients

2021

Inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, are chronic diseases associated with increased morbidity and reduced quality of life. Age may represent a risk factor for adverse events, due to the multimorbidity and polypharmacy, common in elderly patients. Elderly are often not included in clinical trials evaluating efficacy and safety of study drugs for the treatment of inflammatory bowel diseases. Several drugs, such as aminosalicylates, systemic corticosteroids, immunosuppressant drugs, biological drugs and Janus Kinase inhibitors, are available for the management of inflammatory bowel diseases. With the increasing spectrum of therapeutic options, it is th…

safetyPolypharmacydrug-drug interactionsmedicine.medical_specialtybusiness.industryEndocrinology Diabetes and MetabolismInflammatory bowel disease elderly patients safety drug-drug interactionsGastroenterologyDiseaseelderly patientsmedicine.diseaseInflammatory bowel diseaseUlcerative colitisInflammatory bowel diseaseVedolizumabClinical trialUstekinumabInternal MedicinemedicineAdverse effectIntensive care medicinebusinessmedicine.drugMinerva Gastroenterology
researchProduct