Search results for " Endoscopic Retrograde"

showing 10 items of 38 documents

Cholangitis prevention in endoscopic Klatskin tumor palliation: air cholangiography technique.

2009

INTRODUCTION: Endoscopic biliary drainage is the treatment of choice for inoperable hilar cholangiocarcinoma (so-called Klatskin tumor). Cholangitis is the main complication post-endoscopic retrograde cholangiopancreatography (ERCP) in Klatskin patients, specially when medium contrast is injected into biliary tree that could not be subsequently drained. Bacterial cholangitis is the principal cause of mortality in these patients. The aim of this study is to analyze cholangitis rate resulting from the use of air versus iodine contrast to obtain cholangiography during ERCP. METHODS: In 9 years, 188 inoperable Klatskin patients were recruited and divided into two groups: iodine (A) or air (B) c…

medicine.medical_specialtyCholangitisPopulationContrast MediaHepatic Duct CommonCohort StudiesCholangiographymedicineHumanseducationRetrospective StudiesCholangiopancreatography Endoscopic Retrogradeeducation.field_of_studymedicine.diagnostic_testERCP Klatskinbusiness.industryPalliative CareCholangitiair cholangiographyVascular surgerymedicine.diseasedigestive system diseasesIopamidolCardiac surgeryPneumoradiographySettore MED/18 - Chirurgia GeneraleKlatskin tumorBile Duct NeoplasmsCardiothoracic surgeryStentsSurgeryRadiologyComplicationbusinessKlatskin TumorAbdominal surgery
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Is ERCP manometry useful in the choice of treatment of stones of the common bile duct?

1988

To verify the appropriateness of sphincterotomy as the treatment of choice of choledocholithiasis, since 1980 we have been using endoscopic retrograde cholangiopancreatographic (ERCP) manometry of the sphincter of Oddi (SO). This method allows direct investigation of SO motor activity and provides useful information regarding the presence of benign papillary stenosis (BPS). Thirty-four patients were investigated because the radiological examination indicated BPS might be present. Of these, 20 had common bile duct (CBD) stones, while the remaining 14 presented with biliarylike pain and one or more of the following: CBD dilation (larger than 12 mm); emptying of the ERCP contrast medium took l…

AdultMalemedicine.medical_specialtyManometryConstriction PathologicGallstonesInternal medicineSphincter of OddiPressureMedicineHumansSphincter of OddiAgedCholangiopancreatography Endoscopic RetrogradeCommon bile ductmedicine.diagnostic_testbusiness.industryHepatologyMiddle Agedmedicine.diseaseEndoscopySurgerymedicine.anatomical_structureBiliary tractAbnormal Liver Function TestSurgeryFemalePeristalsisPapillary stenosisbusinessAbdominal surgerySurgical endoscopy
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Biliopancreatic Endoscopy in Altered Anatomy

2021

Background and Objectives: Anatomical post-surgical alterations of the upper gastrointestinal (GI) tract have always been challenging for performing diagnostic and therapeutic endoscopy, especially when biliopancreatic diseases are involved. Esophagectomy, gastrectomy with various reconstructions and pancreaticoduodenectomy are among the most common surgeries causing upper GI tract alterations. Technological improvements and new methods have increased the endoscopic success rate in these patients, and the literature has been rapidly increasing over the past few years. The aim of this systematic review is to identify evidence on the available biliopancreatic endoscopic techniques performed i…

Endoscopic ultrasoundMedicine (General)medicine.medical_treatmentCochrane LibraryEndosonographyERCPR5-920GastrectomyMedicinedifficult biliary stonesHumansProspective StudiesRetrospective StudiesCholangiopancreatography Endoscopic RetrogradeEndoscopic retrograde cholangiopancreatographyUSmedicine.diagnostic_testbusiness.industryinterventional EUSRetrospective cohort studyGeneral MedicineAnatomyPancreaticoduodenectomyEndoscopyEsophagectomyTherapeutic endoscopyFNBSystematic Reviewbusinessbiliopancreatic endoscopyCH-EUSMedicina
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Redox signaling in acute pancreatitis

2015

Acute pancreatitis is an inflammatory process of the pancreatic gland that eventually may lead to a severe systemic inflammatory response. A key event in pancreatic damage is the intracellular activation of NF-κB and zymogens, involving also calcium, cathepsins, pH disorders, autophagy, and cell death, particularly necrosis. This review focuses on the new role of redox signaling in acute pancreatitis. Oxidative stress and redox status are involved in the onset of acute pancreatitis and also in the development of the systemic inflammatory response, being glutathione depletion, xanthine oxidase activation, and thiol oxidation in proteins critical features of the disease in the pancreas. On th…

NecrosisGSH reduced glutathioneSTAT3 signal transducer and activator of transcription 3ERK extracellular signal-regulated kinasesClinical BiochemistryCCK cholecystokininTRAFs TNF receptor associated factorsReview ArticleIκB kinasePharmacologymedicine.disease_causeBiochemistrySHP small heterodimer partnerSTIM1 stromal interaction molecule 1chemistry.chemical_compoundHATs histone acetyltransferasesMedicineASK1GCL glutamate cysteine ligaseTNF-α tumor necrosis factor alphaIKK IκB kinaseNOS nitric oxide synthaseAcute inflammationHIF hypoxia inducible factorlcsh:QH301-705.5NF-κB nuclear factor kappa BDAMPs damage-associated molecular pattern moleculeslcsh:R5-920biologyGSSG oxidized glutathioneNF-kappa BNLRs nucleotide-binding oligomerization domain (NOD) like receptorsTRADD tumor necrosis factor receptor type 1-associated DEATH domain proteinTRPC3 transient receptor potential channel 3VEGF vascular endothelial growth factorGlutathioneTNFR tumor necrosis factor receptorHMGB1 high-mobility group Box 1 proteinIP3R inositol 145-trisphosphate receptor type 3VCAM-1 Vascular Cell adhesion protein 1Acute DiseaseJNK c-Jun N-terminal kinaseAcute pancreatitisTLRs toll-like receptorsmedicine.symptomlcsh:Medicine (General)Oxidation-ReductionAP-1 activator protein-1Signal TransductionmRNA messenger ribonucleic acidHMGB1ASC apoptosis-associated speck-like protein containing a carboxy-terminal CARDRNS reactive nitrogen speciesPTPs protein tyrosine phosphatasesROS reactive oxygen speciesNADH nicotinamide adenine dinucleotidepHe extracellular pHFAEE fatty acid ethyl estersAP acute pancreatitisHumansXanthine oxidaseCBP CREB-binding proteinRyR endoplasmic reticulum membrane ryanodine receptorsMDA malondialdehydeNO nitric oxideXO xanthine oxidaseASK1 apoptosis signal-regulating kinase-1business.industryOrganic ChemistryAutophagyNADPH nicotinamide adenine dinucleotide phosphateHDACs histone deacetylasesmedicine.diseaseCARS compensatory anti-inflammatory response syndromeXDH xanthine dehydrogenaseIL interleukinIκB inhibitor of kappa BAcute pancreatitisETC Electron transport chainPancreatitisMKPs MAPK phosphatasesSAP severe acute pancreatitischemistrylcsh:Biology (General)DTT dithiothreitolOxidative stressNAC N-acetyl cysteineImmunologybiology.proteinCalciumLysosomesReactive Oxygen SpeciesbusinessMAPK mitogen-activated protein kinaseOxidative stressERCP endoscopic retrograde cholangiopancreatographyRedox Biology
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Disconnected pancreatic duct syndrome: complete pancreas transection secondary to acute pancreatitis

2016

Disconnected pancreatic duct syndrome is a serious complication of acute pancreatitis which is defined by a complete discontinuity of the pancreatic duct, such that a viable side of the pancreas remains isolated from the gastrointestinal tract. This pancreatic disruption is infrequently observed in the clinical practice and its diagnostic and therapeutic management are controversial. We present an extreme case of disconnected pancreatic duct syndrome with complete duct disruption and pancreatic transection following acute pancreatitis, as well as the diagnostic and therapeutic processes carried out.

medicine.medical_specialtyPancreatic pseudocysteducation030230 surgeryGastroenterology03 medical and health sciences0302 clinical medicineInternal medicineMedicineHumanslcsh:RC799-869PancreasPancreatic ductCholangiopancreatography Endoscopic RetrogradeGastrointestinal tractbusiness.industryGastroenterologyPancreatic DuctsGeneral MedicineMiddle Agedmedicine.diseaseAdenocarcinoma MucinousMagnetic Resonance ImagingPancreatic Neoplasmsmedicine.anatomical_structurePancreatitisAcute pancreatitisPancreatitis030211 gastroenterology & hepatologyFemalelcsh:Diseases of the digestive system. GastroenterologybusinessPancreasComplicationTomography X-Ray ComputedDuct (anatomy)Revista Espanola de Enfermedades Digestivas
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Endoscopic cytology in biliary strictures. Personal experience

2008

The differential diagnosis between malignant and benign biliary strictures is the cornerstone of the management of jaundiced patients. The aim of our study is to define the role of cytology of the bile withdrawn during endoscopic retrograde cholangiopancreatography (ERCP), to reach a diagnosis of the nature of biliary stricture.This retrospective study was conducted on 67 consecutive patients affected of ingravescent obstructive jaundice who underwent ERCP+/-PTE (percutaneous transhepatic endoscopic)+bile withdrawn+stenting. We founded hilar stricture in 21 patients (31.3%), middle third the common duct stricture in 17 (25.3%), and lower third stricture in 28 patients (41.4%). In one patien…

MaleBile Duct DiseasesConstriction PathologicSensitivity and SpecificityCholangiocarcinomaDiagnosis DifferentialPredictive Value of TestsBileHumansAgedRetrospective StudiesAged 80 and overCholangiopancreatography Endoscopic RetrogradeCitology biliary cancerChi-Square DistributionBiopsy NeedleMiddle AgedPancreatic NeoplasmsJaundice ObstructiveSettore MED/18 - Chirurgia GeneraleTreatment OutcomeBile Duct NeoplasmsDrainageFemaleStentsFollow-Up Studies
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Pharmacology of the Sphincter of Oddi

1988

The sphincter of Oddi is the smooth muscle connection between the bile duct and the duodenum. Its physiological function is associated with a regular motility characterized by phasic contractions superimposed on the sphincter of Oddi baseline pressure. Recently introduced ERCP-manometry permits further studies of sphincter of Oddi pharmacology. A number of drugs have so far been studied. Sedatives of the diazepam type had no effect on the sphincter, while butylscopolaminium bromide, a typical neurotropic agent, brings about cessation of the sphincter motility for 3-8 minutes. Hymecromon lowered the sphincter baseline pressure from 9.8 to 7.8 mmHg. A 1.2 mg sublingual dose of nitroglycerin, …

Cholangiopancreatography Endoscopic RetrogradeAmpulla of VaterCommon bile ductManometrybusiness.industryBile ductdigestive oral and skin physiologyGastroenterologyPharmacologydigestive systemSecretinPentazocinemedicine.anatomical_structurePancreatic juiceSphincter of Oddiotorhinolaryngologic diseasesmedicineDuodenumHumansSphincterSphincter of Oddibusinessmedicine.drugEndoscopy
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Endoscopic papillary large balloon dilation in patients with large biliary stones and periampullary diverticula: Results of a multicentric series.

2018

Abstract Introduction Stone extraction represents the most frequent indication for endoscopic retrograde cholangiopancreatography (ERCP). Endoscopic papillary large balloon dilation (EPLBD) is a recent introduced approach consisting of an endoscopic papillary large balloon dilation following limited endoscopic sphyncterotomy (ES), which has been proven to be safe and effective for extraction of large common bile duct (CBD) stones. Peri-ampullary diverticula (PAD) are described in 10–20% of patients undergoing ERCP. Aim of our study is to evaluate efficacy and safety of EPLBD for the extraction of large biliary stones in patients with PAD. Methods The prospectively collected endoscopy databa…

Malemedicine.medical_specialtyAmpulla of VaterDilation assisted stone extractionTherapeutic ERCPEndoscopic papillary large balloon dilationGallstonesDASE Dilation assisted stone extraction Difficult choledocholithiasis03 medical and health sciencesSphincterotomy Endoscopic0302 clinical medicineInternal medicinemedicineStone extractionHumansLarge bile duct stoneIn patientAgedRetrospective StudiesAged 80 and overCholangiopancreatography Endoscopic RetrogradeEndoscopic retrograde cholangiopancreatographyHepatologyCommon bile ductmedicine.diagnostic_testbusiness.industryGastroenterologyDASEHepatologyMiddle AgedDilatationSurgeryEndoscopyDiverticulummedicine.anatomical_structureLogistic ModelsTreatment OutcomeItalyDifficult choledocholithiasi030220 oncology & carcinogenesisBalloon dilation030211 gastroenterology & hepatologyFemaleEPLBDbusinessBILIARY STONESDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
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Impact of Gallbladder Status on the Outcome in Patients with Retained Bile Duct Stones Treated with Extracorporeal Shockwave Lithotripsy

2002

BACKGROUND AND STUDY AIMS The use of endoscopic therapy in combination with lithotripsy techniques has become increasingly common in patients with complicated common bile duct stones. In many units, although this is controversial, cholecystectomy is then performed, because of possible subsequent cholecystitis and recurrence of choledocholithiasis. The aim of this study was to investigate whether gallbladder status influences the long-term outcome in patients after extracorporeal shockwave lithotripsy (ESWL) of common bile duct stones. PATIENTS AND METHODS Recruited for the study were 120 patients with an average age of 68 years (range 28 - 86). They were selected from 137 consecutive patien…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentGallstonesLithotripsyRecurrenceRisk FactorsLithotripsymedicineHumansCholecystectomyAgedAged 80 and overCholangiopancreatography Endoscopic RetrogradeEndoscopic retrograde cholangiopancreatographyCommon bile ductmedicine.diagnostic_testbusiness.industryBile ductGallbladderGastroenterologyMiddle Agedmedicine.diseaseSurgeryTreatment Outcomemedicine.anatomical_structureElective Surgical ProceduresBiliary tractCholecystitisFemaleCholecystectomybusinessEndoscopy
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Hemosuccus pancreaticus--a rare cause of gastrointestinal bleeding: diagnosis and interventional radiological therapy.

2000

Hemorrhage from the pancreatic duct, i.e. hemosuccus pancreaticus (HP), is a rare cause of gastrointestinal bleeding. Pancreatic hemosuccus is usually due to the rupture of an aneurysm of a visceral artery, most likely the splenic artery, in chronic pancreatitis. Other causes of HP are rare. We present a case of HP in a female patient with no history but with positive findings of chronic calcifying pancreatitis upon ultrasonographic investigation, computed tomography scan, and endoscopic retrograde cholangiopancreatography. With detectable fresh blood in the descending duodenum, angiography of the celiac artery revealed an aneurysm of the splenic artery as the suspected cause of intermitten…

medicine.medical_specialtyGastrointestinal bleedingPancreatic diseaseSplenic arteryAneurysm RupturedRadiology InterventionalBlood Vessel Prosthesis ImplantationCeliac arterymedicine.arteryHemosuccus pancreaticusmedicineHumansPancreasPancreatic ductCholangiopancreatography Endoscopic RetrogradeEndoscopic retrograde cholangiopancreatographymedicine.diagnostic_testbusiness.industryGastroenterologyAngiographyPancreatic DuctsMiddle Agedmedicine.diseaseSurgerymedicine.anatomical_structurePancreatitisChronic DiseasePancreatitisFemaleStentsRadiologybusinessGastrointestinal HemorrhageSplenic ArteryEndoscopy
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