Search results for " Endothelium"

showing 10 items of 63 documents

Structural Basis of Tumoral Angiogenesis

2003

Mammalian cells require oxygen and nutrients for metabolism and growth. In all cases tissues possess a vascular and lymphatic network assuring the supply of these needs within 200 to 250µm. Multicellular organisms that grow beyond this size require the recruitment of new blood vessels, although some normal tissues are devoid of specific vascularization (cartilage, cornea, epidermis), obtaining their oxygen and metabolic supply through perfusion

Epidermis (botany)AngiogenesisCartilagegovernment.form_of_governmentBiologyCell biologyVascular endothelial growth factorchemistry.chemical_compoundLymphatic EndotheliumMulticellular organismmedicine.anatomical_structureLymphatic systemchemistrymedicinegovernmentVasculogenic mimicry
researchProduct

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis

2017

BackgroundDysbiosis has been recently demonstrated in patients with ankylosing spondylitis (AS) but its implications in the modulation of intestinal immune responses have never been studied. The aim of this study was to investigate the role of ileal bacteria in modulating local and systemic immune responses in AS.MethodsIleal biopsies were obtained from 50 HLA-B27+ patients with AS and 20 normal subjects. Silver stain was used to visualise bacteria. Ileal expression of tight and adherens junction proteins was investigated by TaqMan real-time (RT)-PCR and immunohistochemistry. Serum levels of lipopolysaccharide (LPS), LPS-binding protein (LPS-BP), intestinal fatty acid-BP (iFABP) and zonulin…

Genetics and Molecular Biology (all)Fatty Acid-Binding ProteinAnkylosing SpondylitisMonocyteBiochemistryMonocytesTransgenic0302 clinical medicineIntestinal MucosaMembrane GlycoproteinsZonulinCadherinsAdherens JunctionUp-RegulationAntigenAcute DiseaseMembrane GlycoproteinRats TransgenicInfectionHumanAnkylosingImmunologyGeneral Biochemistry Genetics and Molecular BiologyArticlePermeabilityTight Junctions03 medical and health sciencesRheumatologyAntigens CDIleumAnti-Bacterial AgentHuman Umbilical Vein Endothelial CellsHumansRNA MessengerEndotheliumProtein PrecursorsAnkylosing SpondylitiBiochemistry Genetics and Molecular Biology (all)BacteriaAnimalmedicine.diseaseDysbiosiSettore MED/16 - Reumatologia030104 developmental biologychemistryCase-Control StudiesImmunologyRatCarrier ProteinsAcute-Phase ProteinsSpondylitis0301 basic medicineLipopolysaccharidesLipopolysaccharideMessengerAcute-Phase ProteinGene Expressionchemistry.chemical_compoundIntestinal mucosaImmunology and AllergyMembrane ProteinHLA-B27 AntigenCaco-2 CellTight junctionTight JunctionAdherens JunctionsIleitisIleitiAnti-Bacterial AgentsCDmedicine.anatomical_structureAnkylosing Spondylitis; Infections; Inflammation; Acute Disease; Acute-Phase Proteins; Adherens Junctions; Animals; Anti-Bacterial Agents; Antigens CD; Bacteria; Caco-2 Cells; Cadherins; Carrier Proteins; Case-Control Studies; Cholera Toxin; Chronic Disease; Dysbiosis; Endothelium; Fatty Acid-Binding Proteins; Gene Expression; HLA-B27 Antigen; Human Umbilical Vein Endothelial Cells; Humans; Ileitis; Ileum; Interleukin-8; Intestinal Mucosa; Junctional Adhesion Molecule A; Lipopolysaccharides; Membrane Glycoproteins; Membrane Proteins; Monocytes; Permeability; RNA Messenger; Rats; Rats Transgenic; Spondylitis Ankylosing; Tight Junctions; Up-Regulationmedicine.symptomCase-Control StudieCholera ToxinHuman Umbilical Vein Endothelial CellLipopolysaccharideInflammationInfectionsFatty Acid-Binding ProteinsAdherens junctionmedicineAnkylosing Spondylitis; Infections; Inflammation; Acute Disease; Acute-Phase Proteins; Adherens Junctions; Animals; Anti-Bacterial Agents; Antigens CD; Bacteria; Caco-2 Cells; Cadherins; Carrier Proteins; Case-Control Studies; Cholera Toxin; Chronic Disease; Dysbiosis; Endothelium; Fatty Acid-Binding Proteins; Gene Expression; HLA-B27 Antigen; Human Umbilical Vein Endothelial Cells; Humans; Ileitis; Ileum; Interleukin-8; Intestinal Mucosa; Junctional Adhesion Molecule A; Lipopolysaccharides; Membrane Glycoproteins; Membrane Proteins; Monocytes; Permeability; RNA Messenger; Rats; Rats Transgenic; Spondylitis Ankylosing; Tight Junctions; Up-Regulation; Immunology and Allergy; Rheumatology; Immunology; Biochemistry Genetics and Molecular Biology (all)AnimalsSpondylitis AnkylosingAntigensSpondyliti030203 arthritis & rheumatologyInflammationHaptoglobinsbusiness.industryMonocyteInterleukin-8Membrane ProteinsRatsJunctional Adhesion Molecule AChronic DiseaseCadherinDysbiosisRNACaco-2 CellsCarrier ProteinbusinessDysbiosis
researchProduct

Removal of Viscoelastic Substances

2000

All viscoelastics should be completely removed from the eye to reduce the likelihood of increased intraocular pressure. Should OVD retention behind the IOL occur, an unstable refraction could result. Residual high molecular viscous substance is transported away through the trabecular meshwork, with delay, possibly resulting in a protracted postoperative IOP increase. To aspirate viscoelastics various techniques as well as instruments with different aspiration/irrigation adjustments have been proposed, a few of which will be described here. Viscoelastic removal involving the simultaneous irrigation and aspiration through a single cannula (Nevyas, 1987) or two separate cannulas (Brauweiler, 1…

Intraocular pressureViscoelastic SubstancesCorneal endotheliumMaterials sciencegenetic structuresCannulaeye diseasesViscoelasticitymedicine.anatomical_structureRefraction (sound)medicinesense organsTrabecular meshworkBiomedical engineering
researchProduct

Entwicklung der Hornhautdicke während der UV-Vernetzungstherapie unter Anwendung verschiedener Kompositionen von Riboflavin-Augentropfen

2011

Background During the UVA-cross-linking treatment in keratoconus patients, the UVA rays are partially absorbed in the stroma of the riboflavin-loaded cornea. This effect protects the corneal endothelium from UVA irradiation damage. The intensity of UVA light reaching the endothelium is inversely correlated with corneal thickness. The common composition of riboflavin eye drops may lead to a marked reduction in corneal thickness increasing the risk of endothelial damage. Patients and methods In a retrospective analysis of 23 UVA-cross-linking procedures on 23 patients we collected data about the pre-, intra- and postoperative corneal thickness (measured with ultrasound). Among these patients …

KeratoconusCorneal endotheliummedicine.medical_specialtygenetic structuresbusiness.industryUltrasoundRiboflavinmedicine.diseaseeye diseasesIntensity (physics)SurgeryOphthalmologyDose–response relationshipmedicine.anatomical_structureCorneaOphthalmologymedicineUva irradiationsense organsbusinessKlinische Monatsblätter für Augenheilkunde
researchProduct

Phenotype characterization of the anti-inflammatory behavior of decidual endothelial cells

2009

LPSendotheliumEndotheliumChemistrymedicine.drug_classImmunologyDeciduaObstetrics and Gynecologydecidua; endothelium; LPSPhenotypeAnti-inflammatoryCell biologymedicine.anatomical_structureReproductive MedicinemedicineImmunology and AllergydeciduaJournal of Reproductive Immunology
researchProduct

On the develpment of the absorbing lymphatic vessel

2007

Lymph vessel endothelium lymphatic system
researchProduct

Lymphocyte transendothelial passage in postcapillary high endothelial venules (HEV) of lymph nodes and aggregate lymph nodules

2003

Lymphocyte endothelium high endothelial venule HEV lymph node
researchProduct

IC3D Classification of Corneal Dystrophies—Edition 2

2015

To update the 2008 International Classification of Corneal Dystrophies (IC3D) incorporating new clinical, histopathologic, and genetic information.The IC3D reviewed worldwide peer-reviewed articles for new information on corneal dystrophies published between 2008 and 2014. Using this information, corneal dystrophy templates and anatomic classification were updated. New clinical, histopathologic, and confocal photographs were added.On the basis of revisiting the cellular origin of corneal dystrophy, a modified anatomic classification is proposed consisting of (1) epithelial and subepithelial dystrophies, (2) epithelial-stromal TGFBI dystrophies, (3) stromal dystrophies, and (4) endothelial d…

Macular corneal dystrophygenetic structuresEndothelial dystrophiesGenetic diseaseStromaEpitheliumGelatinousdrop-like corneal dystrophyCorneaLisch Epithelial Corneal DystrophyCornea pathologyPosteror polymorphous corneal dystrophyCorneal Dystrophies HereditaryPosterior amorphous corneal dystrophyEpithelial-stromal TGFBI dystrophiesMacular corneal dystrophyFleck corneal dystrophyLattice corneal dystrophyPre-Descemet corneal dystrophyCongenital stromal corneal dystrophySubepithelialmucinous corneal dystrophySchnyder corneal dystrophyThiel-Behnke corneal dystrophyPosterior polymorphous corneal dystrophyEpithelial and subepithelial dystrophiesFuchsendothelial corneal dystrophyFleck corneal dystrophyReis-Bücklers corneal dystrophyCongenital hereditary endothelial dystrophyCentralcloudy dystrophy of FrançoisCongenital stromal corneal dystrophyPosterior amorphous corneal dystrophymedicine.medical_specialtyHistologyeducationHereditary diseaseHistopathologyBiologyKeratoconusLisch epithelial corneal dystrophyMeesmann dystrophyNOBowman membraneDescemetmembraneInternational Classification of DiseasesTerminology as TopicOphthalmologyGeneticsmedicineHumansBowman membrane; Centralcloudy dystrophy of François; Confocal microscopy; Confocal microscopy; Congenital corneal endothelial dystrophy and X-linked endothelialdystrophy; Congenital stromal corneal dystrophy; Cornea; Cornea; Cornea dystrophy; Cornea pathology; Descemetmembrane; Endothelial dystrophies; Endothelium; Epithelial and subepithelial dystrophies; Epithelial basement membranedystrophy; Epithelial recurrent erosion dystrophies; Epithelial-stromal TGFBI dystrophies; Epithelium; Fleck corneal dystrophy; Fuchsendothelial corneal dystrophy; Gelatinousdrop-like corneal dystrophy; Genetic disease; Genetics; Granular corneal dystrophy type 1; Granular corneal dystrophy type 2; Hereditary disease; Histology; Histopathology; Keratoconus; Lattice corneal dystrophy; Lisch epithelial corneal dystrophy; Macular corneal dystrophy; Meesmann dystrophy; Posterior amorphous corneal dystrophy; Posteror polymorphous corneal dystrophy; Pre-Descemet corneal dystrophy; Reis-Bücklers corneal dystrophy; Schnyder corneal dystrophy; Stroma; Stromal dystrophies; Subepithelialmucinous corneal dystrophy; TGFBI; Thiel-Behnke corneal dystrophy; OphthalmologyEndotheliumEpithelial basement membranedystrophyCornea dystrophyCongenital corneal endothelial dystrophy and X-linked endothelialdystrophymedicine.diseaseeye diseasesConfocal microscopyOphthalmologyGranular corneal dystrophy type 2Granular corneal dystrophy type 1Stromal dystrophiesLattice corneal dystrophysense organsTGFBIEpithelial recurrent erosion dystrophiesCornea
researchProduct

Angiotensin II Induces Neutrophil Accumulation In Vivo Through Generation and Release of CXC Chemokines

2004

Background—Angiotensin II (Ang II) is implicated in the development of cardiac ischemic disorders in which prominent neutrophil accumulation occurs. Ang II can be generated intravascularly by the renin-angiotensin system or extravascularly by mast cell chymase. In this study, we characterized the ability of Ang II to induce neutrophil accumulation.Methods and Results—Intraperitoneal administration of Ang II (1 nmol/L) induced significant neutrophil recruitment within 4 hours (13.3±2.3×106neutrophils per rat versus 0.7±0.5×106in control animals), which disappeared by 24 hours. Maximal levels of CXC chemokines were detected 1 hour after Ang II injection (577±224 pmol/L cytokine-inducible neut…

MaleChemokinemedicine.medical_specialtyEndotheliumCellsInflammationAngiotensin ; Interleukins ; Cells ; Endothelium ; InflammationPulmonary ArteryUmbilical CordRats Sprague-DawleyAngiotensin:CIENCIAS MÉDICAS ::Medicina interna [UNESCO]Physiology (medical)Internal medicineRenin–angiotensin systemCell AdhesionLeukocytesAnimalsHumansMedicineMesenteryRNA MessengerEndotheliumPeritoneal CavityMacrophage inflammatory proteinCells CulturedUNESCO::CIENCIAS MÉDICAS ::Medicina internaInflammationbiologybusiness.industryAngiotensin IIMicrocirculationInterleukinsInterleukin-8Endothelial CellsChemotaxis:CIENCIAS MÉDICAS [UNESCO]Angiotensin IIRatsmedicine.anatomical_structureEndocrinologyNeutrophil InfiltrationUNESCO::CIENCIAS MÉDICASbiology.proteinmedicine.symptomCardiology and Cardiovascular MedicinebusinessChemokines CXCIntravital microscopy
researchProduct

XEN-augmented Baerveldt Implantation for Refractory Childhood Glaucoma: A Retrospective Case Series

2019

Background Tube implants can lead to long-term decompensation of the cornea after decades, in particular in complicated childhood glaucoma, because of a variety of causes including contact between the tube tip and the corneal endothelium. The augmentation of a XEN implant with a Baerveldt (250) tube implant, introduced 2016 by Mermoud et al for refractory glaucoma in adult patients, may reduce this risk in children. In our retrospective study, we report on the XEN-augmented Baerveldt (250) tube implant in children. Patients and methods Ten consecutive patients with refractory childhood glaucoma who underwent XEN-augmented Baerveldt implantation by a single surgeon (F.G.) between January 201…

MaleReoperationmedicine.medical_specialtyIntraocular pressureCorneal endotheliumAdolescentgenetic structuresGlaucomaSurgical FlapsProsthesis ImplantationTonometry Ocular03 medical and health sciencesPostoperative Complications0302 clinical medicineCorneaHumansMedicineDecompensationChildGlaucoma Drainage ImplantsIntraoperative ComplicationsIntraocular PressureRetrospective StudiesSlit lampbusiness.industryHydrophthalmosInfantmedicine.diseaseeye diseasesSurgeryPosterior segment of eyeballOphthalmologyTreatment Outcomemedicine.anatomical_structureChild Preschool030221 ophthalmology & optometryFemalesense organsImplantbusinessSclera030217 neurology & neurosurgeryJournal of Glaucoma
researchProduct