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showing 10 items of 1034 documents
Erratum: Validation of the 2009 TNM version in a large multi-institutional cohort of patients treated for renal cell carcinoma: Are further improveme…
2011
A new edition of the TNM was recently released that includes modifications for the staging system of kidney cancers. Specifically, T2 cancers were subclassified into T2a and T2b (10 cm), tumors with renal vein involvement or perinephric fat involvement were classified as T3a cancers, and those with adrenal involvement were classified as T4 cancers. OBJECTIVE: Our aim was to validate the recently released edition of the TNM staging system for primary tumor classification in kidney cancer. DESIGN, SETTING, AND PARTICIPANTS: Our multicenter retrospective study consisted of 5339 patients treated in 16 academic Italian centers. INTERVENTION: Patients underwent either radical or partial nephrecto…
Linguistic Approach to Support Human Reliability Analysis and Validation Work in Advanced Radiotherapy Technologies
2019
An integrated methodology, that combines Hierarchical Task Analysis (HTA), Cognitive Task Analysis (CTA) and a modified Human Error Assessment and Reduction Technique (HEART), is proposed to identify safety-relevant human actions in innovative and advanced facilities. It is suggested to use in HEART the concept of linguistic expressions for proportion assessment factors. To prove its applicability, a case study is presented. The validation work has related to safety analyses of accidental events that can involve radiological over-exposure of patients during proton therapy treatments carried out by CATANA (Centro di AdroTerapia Applicazioni Nucleari Avanzate) centre, Italy. CATANA is the fir…
Predictability of intraocular lens power calculation after small-incision lenticule extraction for myopia
2019
PURPOSE To evaluate and compare the predictability of intraocular lens (IOL) power calculation after small-incision lenticule extraction (SMILE) for myopia and myopic astigmatism. SETTING Department of Ophthalmology, Philipps University of Marburg, Marburg, Germany. DESIGN Retrospective comparative case series. METHODS Preoperative evaluation included optical biometry using IOLMaster 500 and corneal tomography using Pentacam HR. The corneal tomography measurements were repeated at 3 months postoperatively. The change of spherical equivalent due to SMILE was calculated by the manifest refraction at corneal plane (SMILE-Dif). A theoretical model, involving the virtual implantation of the same…
Multiobjective optimization of an ultrasonic transducer using NIMBUS
2005
The optimal design of an ultrasonic transducer is a multiobjective optimization problem since the final outcome needs to satisfy several conflicting criteria. Simulation tools are often used to avoid expensive and time-consuming experiments, but even simulations may be inefficient and lead to inadequate results if they are based only on trial and error. In this work, the interactive multiobjective optimization method NIMBUS is applied in designing a high-power ultrasonic transducer. The performance of the transducer is simulated with a finite element model, and three design goals are formulated as objective functions to be minimized. To find an appropriate compromise solution, additional pr…
Household Optimism and Borrowing
2012
A unique Finnish household-level data from 1994 to 2009 allow us to measure how households’ financial expectations are related to the subsequent outcomes. We use the difference between the two to measure forecast errors and household optimism and link the errors to households’ borrowing behaviour. We find that households making greatest optimistic forecast errors carry greater levels of debt and are most likely to suffer from excessive debt loads (overindebtedness). They also are less attentive to forecast errors than their pessimistic counterparts when forming their expectations for a subsequent period.
A comparison of different optimization algorithms for retrieving aerosol optical depths from satellite data: an example of using a dual-angle algorit…
2011
Optimization techniques are often used in remote sensing retrieval of surface or atmospheric parameters. Nevertheless, different algorithms may exhibit different performances for the same optimization problem. Comparison of some classic optimization approaches in this article aims to select the best method for retrieving aerosol opacity, or even for other parameters, from remotely sensed data. Eight frequently used optimization algorithms were evaluated using both simulated data and actual AATSR advanced along track scanning radiometer data. Several typical land cover types and aerosol opacity levels were also considered in the simulations to make the tests more representative. It was obser…
Guaranteed lower bounds for cost functionals of time-periodic parabolic optimization problems
2019
In this paper, a new technique is shown for deriving computable, guaranteed lower bounds of functional type (minorants) for two different cost functionals subject to a parabolic time-periodic boundary value problem. Together with previous results on upper bounds (majorants) for one of the cost functionals, both minorants and majorants lead to two-sided estimates of functional type for the optimal control problem. Both upper and lower bounds are derived for the second new cost functional subject to the same parabolic PDE-constraints, but where the target is a desired gradient. The time-periodic optimal control problems are discretized by the multiharmonic finite element method leading to lar…
A new technique to determine vertical dimension of occlusion from anthropometric measurement of interpupillary distance
2014
Background: A number of techniques are being practiced for the evaluation of VDO, but none of them is scientifically more accurate than other. Each method advocated has its own limitations. Objectives: The purpose of this study was to find correlation between vertical dimension of occlusion (VDO) and interpupillary distance (IPD). Material and Methods: A cross-sectional study was conducted on 400 dentate subjects comprising of 200 males and 200 females. Anthropometric measurement of VDO was recorded clinically using modified digital vernier caliper. Also, a standardized digital photograph of face was generated from the frontal aspect using a digital camera for the measurement of IPD in mill…
Assessment of the rate of force development scaling factor for the hip muscles
2014
Introduction: The aim of this study was to evaluate test feasibility, validity, and reproducibility of the rate of force development scaling factor (RFD-SF) for the hip muscles. Methods: Feasibility was assessed as the testing compliance, validity as the ability to compute the RFD-SF from a linear regression, and reproducibility with a test–retest design in 20 healthy subjects. Reliability and agreement (reproducibility) were evaluated using intraclass correlation coefficient (ICC3,1) and percent standard error of measurement (SEM), respectively. Results: The RFD-SF testing protocol was completed successfully by all subjects, although the analysis had to be modified for hip rotators. Reliab…
Multiple Cost Functions and Regularization Options for Improved Retrieval of Leaf Chlorophyll Content and LAI through Inversion of the PROSAIL Model
2013
Abstract: Lookup-table (LUT)-based radiative transfer model inversion is considered a physically-sound and robust method to retrieve biophysical parameters from Earth observation data but regularization strategies are needed to mitigate the drawback of ill-posedness. We systematically evaluated various regularization options to improve leaf chlorophyll content (LCC) and leaf area index (LAI) retrievals over agricultural lands, including the role of (1) cost functions (CFs); (2) added noise; and (3) multiple solutions in LUT-based inversion. Three families of CFs were compared: information measures, M-estimates and minimum contrast methods. We have only selected CFs without additional parame…