Search results for " Exposure"

Abnormal peripubertal development of the rat mammary gland following exposure in utero and during lactation to a mixture of genistein and the food co…

2012

The impact of early exposure to endocrine disruptor mixtures on mammary gland development is poorly known. Here, we identify the effects of a conception to weaning exposure of rats to the phytoestrogen genistein (G) and/or the antiandrogen vinclozolin (V) at 1 mg/kg-d, alone or in association. Using several approaches, we found that G- and GV-exposed rats displayed significantly greater epithelial branching and proliferation, wider terminal end buds than controls at PND35, as well as ductal hyperplasia and periductal fibrosis. Focal branching defects were present in V-exposed rats. An increased ER and AR expression was observed in G- and CV- as compared to V-exposed rats at PND35. Surprisin…

Impact of information and in-home sensory exposure on liking and willingness to pay: The beginning of Fairtrade labeled coffee in France.

2015

This study was conducted to assess how the Fairtrade label interacts with the perception of intrinsic product characteristics on liking and purchase decisions and to estimate the evolution of this interaction after exposure to the coffees and/or exposure to ethical information. In a first session, 119 consumers gave liking scores for 2 regular and 2 Fairtrade coffees under a blind tasting condition. Then, they were asked to indicate the maximum price they would pay for each product in 2 auctions taking place under different information conditions. In the first auction, participants saw the packaging but did not taste the coffee; in the second auction, they could both taste the coffee and se…

Association between Asthma Control and Exposure to Greenness and Other Outdoor and Indoor Environmental Factors: A Longitudinal Study on a Cohort of …

2022

Achieving and maintaining asthma control (AC) is the main goal of asthma management. Indoor and outdoor environmental factors may play an important role on AC. The aim of this longitudinal study was to evaluate the association between AC and exposure to greenness and other outdoor or indoor environmental factors in a cohort of asthmatic children. This study involved 179 asthmatic children (5–16 years). Parents were interviewed through a modified version of the SIDRIA questionnaire. AC was assessed at each visit. Exposure to greenness was measured using the normalized difference vegetation index (NDVI). A logistic regression model was applied for assessing risk factors for uncontrolled…

Psychobiological effects of perinatal exposure to odorants in mice. Part II: Behavioural alteration

2010

Early exposure to odorants pre-, post- or transnatally is known to. result in a decreased avoidance or increased preference for these. odorants in mammals. There are also indications that olfactory sensitivity. for these odorants can be affected. We exposed C57-Bl/6. mice of Mor23-GFP and M71-GFP lines to lyral (LY) or acetophenone. (AC), respectively, either transnatally through the water of the. mother (1*10-5 M) or postnatally in air for 1 hr per day (20 ll pure). Animals were weaned on postnatal day 20 (P20), and 3 tests were. performed:. 1) A 3-min exploration test on P20 in a rectangular arena presenting. LY and AC under a wire mesh to measure the time spent in each. half of the arena…

Psychobiological effects of perinatal exposure to odorants in mice. Part II: Behavioural alterations

2010

National audience

Frame fungi on insulated windows.

1985

Insulated windows (fixed triple glass window elements), became common in Finland during and after the energy crisis. Moisture tends to condense along the edges causing mold growth on the frames. Nine houses with insulated glass windows and eight with other types of window were studied. Fungus samples were taken from the window edges and from the inside air and cultivated on malt extract agar. In five of the houses with insulated windows there was visible mold growth on the window edges. The predominant fungus was Aureobasidium pullulans. With other types of windows there was only one case of visible mold. The concentrations of fungi were about the same in the air of houses with both types o…

Efficacy of four cleaning solutions for the decontamination of selected cytotoxic drugs on the different surfaces of an automated compounding system

2018

The automated aseptic preparation of ready-to-administer antineoplastic drug solutions with robotic systems reduces the risk of occupational exposure. However, the surfaces in the preparation area of the robot are to be cleaned by wiping with an appropriate cleaning solution. The aim of the study was to evaluate the cleaning efficacy of four cleaning solutions on four surface materials installed in the APOTECAchemo robot. Predefined amounts of cisplatin (Cis), 5-fluorouracil (5-FU), and cyclophosphamide (CP) were intentionally spread on test plates made of stainless steel, aluminium, polyoxymethylene, and polycarbonate just as installed in the robotic system APOTECAchemo. After drying, the …

Maternal occupational exposure to chemicals and neurocognitive development at 4-5 years of age

2021

Cognitive impairment associated with chronic lead exposure in adults

2018

Abstract Lead (Pb) exposure interferes with many biochemical events present in cells of the central nervous system (neurons and astrocytes) and it can produce a wide spectrum of alterations including cognitive impairment. The review summarizes the main cognitive alterations induced by chronic Pb exposure in adults/older individuals. We have focused on the current state of knowledge concerning the most vulnerable brain areas to Pb exposure that accompanied by the long-lasting neurological effects of Pb in cognitive functions. We tried to correlate the cognitive deficits induced by Pb exposure in animal models during adulthood with those reported in humans. The great interest in whether expos…

Long-Term Exposure to Transportation Noise and Risk for Type 2 Diabetes in a Nationwide Cohort Study from Denmark

2021

Background: Epidemiologic studies have linked transportation noise to increased morbidity and mortality, particularly for cardiovascular outcomes. However, studies investigating metabolic outcomes such as diabetes are limited and have focused only on noise exposures estimated for the loudest residential façade. Objectives: We aimed to examine the influence of long-term residential exposure to transportation noise at the loudest and quietest residential façades and the risk for type 2 diabetes. Methods: Road traffic and railway noise exposures (Lden) at the most and least exposed façades were estimated for all dwellings in Denmark during 1990–2017. Aircraft noise was estimated in 5-dB catego…