Search results for " FEM."

showing 10 items of 2292 documents

Proton-irradiated breast cells: molecular points of view

2019

Abstract Breast cancer (BC) is the most common cancer in women, highly heterogeneous at both the clinical and molecular level. Radiation therapy (RT) represents an efficient modality to treat localized tumor in BC care, although the choice of a unique treatment plan for all BC patients, including RT, may not be the best option. Technological advances in RT are evolving with the use of charged particle beams (i.e. protons) which, due to a more localized delivery of the radiation dose, reduce the dose administered to the heart compared with conventional RT. However, few data regarding proton-induced molecular changes are currently available. The aim of this study was to investigate and descri…

breast cancer cDNA microarray gene signature proton therapy radiation Breast Breast Neoplasms Cell Line Tumor DNA Complementary Dose-Response Relationship Radiation Female Gene Expression Profiling Gene Expression Regulation Neoplastic Humans Inflammation MCF-7 Cells Oligonucleotide Array Sequence Analysis Phenotype Proton Therapy Radiation Tolerance Radiotherapy ProtonsDNA ComplementaryHealth Toxicology and Mutagenesismedicine.medical_treatmentBreast NeoplasmsCell fate determinationRadiation Tolerancegene signature03 medical and health sciences0302 clinical medicineBreast cancerbreast cancerCell Line TumorRegular Papermedicineproton therapyHumansRadiology Nuclear Medicine and imagingBreastClonogenic assayBiologyProton therapyOligonucleotide Array Sequence Analysis030304 developmental biologyInflammationcDNA microarray0303 health sciencesRadiotherapyChemistryGene Expression ProfilingBreast cancer; radiation; cDNA microarray; gene signature; proton therapyCancerDose-Response Relationship RadiationGene signaturemedicine.diseaseGene Expression Regulation NeoplasticGene expression profilingRadiation therapyradiationPhenotype030220 oncology & carcinogenesisMCF-7 CellsCancer researchFemaleProtons
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RECRUITMENT OF BICEPS FEMORIS MUSCLE REGIONS AT DIFFERENT RUNNING SPEEDS

2017

Background The majority of hamstring strain injuries (HSIs) occur in the late swing phase of high-speed running when hamstrings work eccentrically. The proximal region of the biceps femoris (BF) seems to be the most common site of injury. Elongation of the fascicles in eccentric contractions is higher in the proximal region compared to the distal region of BF, but the neural background to this phenomenon is not clear. Objective To examine the region-specificity of BF muscle activity at different running speeds. Design Observational study. Running speeds were randomized. Setting Laboratory, amateur level. Participants Football players without acute injury/illness, and without HSI history wer…

business.industryPhysical Therapy Sports Therapy and RehabilitationStrain (injury)General MedicineIsometric exerciseAnatomyDistal Musclemedicine.diseaseBicepsBiceps femoris muscleMotor unit recruitmentmedicineOrthopedics and Sports MedicineTreadmillbusinessHamstringBritish Journal of Sports Medicine
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The Relevance Of The Preform Design In Coining Processes Of Cupronickel Alloy

2007

Coining is a forging process in which a metallic disk, characterized by a low volume‐surface ratio, is deformed with the aim to impress 3D images on its three surfaces. Due to the large production volumes and, at the same time, to the high quality standards required to the final products in terms of final dimensions, tolerances and surface finishing, such closed‐die, cold forging process requires a careful evaluation and choice of the proper operative parameters. In particular, along with technological parameters as the die velocity, die stroke and lubrication, which, in turn, contribute to affect the pressure values on the die surfaces, and thus the press choice, geometrical parameters as …

business.product_categoryMaterials scienceMechanical engineeringForming processesStrain rateFinite element methodForgingCoining Cupronickel FEMLubricationDie (manufacturing)Coining (metalworking)businessSettore ING-IND/16 - Tecnologie E Sistemi Di LavorazioneSurface finishing
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Analytical bonding criteria for joint integrity prediction in friction stir welding of aluminum alloys

2014

Abstract In this study, two bonding criteria, previously used for porthole die extrusion, are applied to FSW starting from the local value of the main field variables calculated through a specifically developed 3D numerical model of the process. Their applicability and effectiveness have been assessed through an experimental and numerical campaign carried out with the main process parameters varying in a wide range. The pressure–time–flow criterion was demonstrated to be better suited for FSW processes when large welding speed is used.

business.product_categoryMaterials scienceMetallurgyMetals and AlloysProcess (computing)Mechanical engineeringWeldingIndustrial and Manufacturing EngineeringFinite element methodComputer Science Applicationslaw.inventionlawModeling and SimulationCeramics and CompositesRange (statistics)Die (manufacturing)Friction stir weldingExtrusionbusinessJoint (geology)Friction stir welding Aluminum alloys FEM Bonding criterionJournal of Materials Processing Technology
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Feminismo, identidad y religión en el Mundo Árabe

2017

Las recientes revoluciones árabes han sido el escenario de reactivación de la lucha feminista en medio de tensiones y conflictos en torno a las relaciones de género. Después de más de un siglo de lucha, las activistas árabes siguen denunciando la discriminación y la persistencia de las estructuras de dominación patriarcal, poniendo así de manifiesto que los temas debatidos desde el nacimiento del feminismo árabe no solo no han sido resueltos, sino que vuelven a resurgir con cada crisis política y social. Este artículo tiene como objetivo analizar las causas de la persistencia de la discriminación de las mujeres a pesar de los importantes cambios sociales. Mediante un análisis histórico que …

cambio socialfeminismoreligiónrevoluciónidentidadNacionalisme i feminisme
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TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells

2015

Metastatic growth in breast cancer (BC) has been proposed as an exclusive property of cancer stem cells (CSCs). However, formal proof of their identity as cells of origin of recurrences at distant sites and the molecular events that may contribute to tumor cell dissemination and metastasis development are yet to be elucidated. In this study, we analyzed a set of patient-derived breast cancer stem cell (BCSC) lines. We found that in vitro BCSCs exhibit a higher chemoresistance and migratory potential when compared with differentiated, nontumorigenic, breast cancer cells (dBCCs). By developing an in vivo metastatic model simulating the disease of patients with early BC, we observed that BCSCs…

cancer stem cellsTAZAnimals; Biomarkers Tumor; Breast Neoplasms; Cell Line Tumor; Disease-Free Survival; Female; Gene Expression Regulation Neoplastic; Humans; Mice; Neoplasm Metastasis; Neoplasm Recurrence Local; Neoplastic Stem Cells; Transcription Factors; Xenograft Model Antitumor AssaysCancer ResearchBioinformaticschemotherapyMetastasistaz; breast cancerMiceNeoplasm Metastasiseducation.field_of_studyTumorIntracellular Signaling Peptides and ProteinsCell cycleGene Expression Regulation NeoplasticLocalNeoplastic Stem Cellsbreast cancer; cancer stem cells; chemotherapy; metastasis; TAZ; Animals; Biomarkers Tumor; Breast Neoplasms; Cell Line Tumor; Disease-Free Survival; Female; Gene Expression Regulation Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Mice; Neoplasm Metastasis; Neoplasm Recurrence Local; Neoplastic Stem Cells; Xenograft Model Antitumor Assays; Molecular Biology; Genetics; Cancer ResearchFemaleStem cellPopulationBreast NeoplasmsBiologyDisease-Free SurvivalCell Linebreast cancer cancer stem cells TAZBreast cancerbreast cancerCancer stem cellSettore MED/04 - PATOLOGIA GENERALECell Line TumormedicineBiomarkers TumorGeneticsmetastasisAnimalsHumanseducationMolecular BiologyHippo signaling pathwayNeoplasticCancermedicine.diseaseXenograft Model Antitumor AssaysNeoplasm RecurrenceGene Expression RegulationTranscriptional Coactivator with PDZ-Binding Motif ProteinsCancer researchTrans-ActivatorsNeoplasm Recurrence LocalBiomarkersTranscription Factors
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Kanony kobiecego piękna fizycznego w reklamie telewizyjnej i internetowej

2016

Niniejsze opracowanie dotyczy kobiecego piękna w aspekcie fizycznym w reklamie telewizyjnej i internetowej, a także tożsamości kobiety w popkulturze. Analizowane wizerunki bohaterek wybranych komunikatów zostały podzielone na dwa typy: kobieta zwyczajna (w tym gospodyni domowa i specjalistka) oraz kobieta idealna (w tym aktywistka, kobieta sukcesu oraz zmysłowa). Ukazano także związek schematów istniejących w reklamach z funkcjonującymi w społeczeństwie stereotypami dotyczącymi płci. Ustalono, w jaki sposób poszczególne typy bohaterek są ukazywane w reklamach oraz jakie cechy są kanoniczne dla wizerunku tych kobiet.

canon of female beautyinternet advertisementstereotypy płciwoman in advertisementreklama internetowakanon kobiecego pięknagender stereotypeskobieta w reklamiereklama telewizyjnaTV advertisement
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Photoinduced charge separation in functional carbon-silver nanohybrids

2022

In recent times, nanoscience is devoting growing interest to the easy assembly of well-established nanomaterials into hybrid nanostructures displaying new emerging features. Here, we study the photophysicochemical response of binary nanohybrids obtained by the spontaneous coupling of luminescent carbon dots to silver nanoparticles with controlled surface charge. Evidence of the successful coupling is obtained by steady-state and time resolved optical measurements and further confirmed by direct imaging. We demonstrate strong interactions within nanohybrids, which can be modelled in terms of a sub-picosecond electron transfer from photoexcited carbon dots to silver nanoparticles. Accordingly…

carbon dots femtosecond charge transferSettore FIS/01 - Fisica SperimentaleGeneral Physics and AstronomyPhysical and Theoretical Chemistry
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Cardiovascular Health in Migrants. Current status and issues for prevention. A Collaborative Multidisciplinary Task Force Report

2014

OBJECTIVES: To review information on cardiovascular health and migration, to stress the attention of researchers that much needs to be done in the collection of sound data in Italy and to allow policy makers identifying this issue as an important public health concern. BACKGROUND: In Italy, the rate of immigrants in the total number of residents increased from 2.5% in 1990 to 7.4% in 2010, and currently exceeds 10% in regions such as Lombardia, Emilia Romagna and Toscana. METHODS: A consensus statement was developed by approaching relevant Italian national scientific societies involved in cardiovascular prevention. Task force members were identified by the president and/or the boards of eac…

cardiovascular riskMalemedicine.medical_specialtyEconomic growthcardiovascular risk; ethnic; ethnicity; global health; immigration; migrant; minorities; Cardiovascular Diseases; Diabetes Mellitus; Europe; Female; Health Status; Humans; Kidney Diseases; Male; Overweight; Transients and Migrants; Cardiology and Cardiovascular Medicine; Medicine (all)Kidney Diseasemedia_common.quotation_subjectHealth StatusImmigrationEthnic groupglobal healthHealth StatuminoritieCardiovascular DiseaseGlobal healthmedicineDiabetes Mellitusmedia_common.cataloged_instanceHumansEuropean unionethnicmedia_commonTransients and Migrantscardiovascular risk ethnic ethnicity global health immigration migrant minoritiesbusiness.industryPublic healthMedicine (all)Diabetes MellituGeneral MedicineOverweightminoritiesSettore MED/11 - Malattie Dell'Apparato CardiovascolareEuropemigrantCardiovascular Diseasesethnic; global health; immigration; migrant; minorities; cardiovascular risk; ethnicitySurvey data collectionethnicitySocial exclusionKidney DiseasesFemalebusinessCardiology and Cardiovascular MedicineDiversity (politics)immigrationHuman
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The primary structural photoresponse of phytochrome proteins captured by a femtosecond X-ray laser

2020

Please check the README file for more information about the dataset.

chromophore-binding domains of Bacterial phytochromeX-ray Free-electorn LasersXFELData_FILESBL3: EH2Serial Femtosecond CrystallographyGeneralLiterature_MISCELLANEOUSComputingMethodologies_COMPUTERGRAPHICSSACLA
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