Search results for " FOLLOW-UP"

Effect of aspirin on renal disease progression in patients with type 2 diabetes: A multicenter, double-blind, placebo-controlled, randomized trial. T…

2017

Background Type 2 diabetes mellitus (T2DM) is one of the most common causes of chronic kidney disease and kidney failure. It has been estimated that the annual decline of estimated glomerular filtration rate (eGFR) among patients with T2DM is approximately 2.0-2.5 mL min−1 y−1. Cyclooxygenase-dependent eicosanoids, such as 11-dehydro-thromboxane (Tx)B2, are increased in T2DM patients and are potentially involved in the regulation of renal blood flow. Animal models showed that cyclooxygenase inhibitors, such as aspirin, are associated with improvements in renal plasma flow and eGFR values. Hypothesis The primary end point of the LEDA trial is to evaluate the 1-year decline of eGFR in T2DM pa…

Integrated treatment of first episode psychosis with online training (e-learning): study protocol for a randomised controlled trial

2014

Background: The integrated treatment of first episode psychosis has been shown to improve functionality and negative symptoms in previous studies. In this paper, we describe a study of integrated treatment (individual psychoeducation complementary to pharmacotherapy) versus treatment as usual, comparing results at baseline with those at 6-month re-assessment (at the end of the study) for these patients, and online training of professionals to provide this complementary treatment, with the following objectives: 1) to compare the efficacy of individual psychoeducation as add-on treatment versus treatment as usual in improving psychotic and mood symptoms; 2) to compare adherence to medication,…

VALVULOPATIA AORTICA: FOLLOW-UP IN UN GRUPPO DI PAZIENTI SOTTOPOSTI AD INTERVENTO DI SOSTITUZIONE VALVOLARE

2007

Le passage de Haies: De la réalité sportive en heptathlon à la réalité subjective d'Emma

2006

The major dimension of this article is to point out the importance of psychological follow-up with sporting teenagers. Emma's example illustrates the inherent transitions from this period of age in the specific context of the high level sport. For Emma, the passage of hurdle becomes the metaphor of its psychical conflict. The counter performance which appears in the passage of hurdle announces its ambivalence with regard to its personal history within realities of sport cultures. This making sense of the sporting problems within the framework of the psychological follow-up can help to exceed this difficulty of passage and to support its engagement like subject of its own desire on the way o…

The 10‐year treatment outcome of open dialogue‐based psychiatric services for adolescents: A nationwide longitudinal register‐based study

2022

Aim: To evaluate the 10-year treatment outcomes and cost-effectiveness of adolescents' mental health treatment initiated under the social network-oriented open dialogue (OD) approach. -- Methods: This longitudinal register-based study included all persons who, for the first time, received psychiatric treatment in Finland during the period 1 January 2003–31 December 2008, and who were aged 13–20 at onset (n = 44 868). The OD group included all persons whose treatment commenced in the Western Lapland catchment area (n = 780), this being the only region in Finland where OD covered the entire mental healthcare service at the time of inclusion. The comparison group (CG) included the rest of Finl…

The rationale for and practice of EIA follow-up: an analysis of Finnish road projects

2015

Follow-up is often considered to be a weak or even missing element in environmental impact assessment (EIA). Though it is recognized that follow-up practices could provide useful opportunities to learn from projects’ actual consequences, the practice is criticized for not achieving this goal. In this paper, we aim to clarify the relationship between the theoretical rationale for EIA follow-up and the actual practices carried out in a Finnish EIA context. An empirical analysis was performed with follow-up documents. The findings indicate that follow-ups focused on dealing with environmental impacts related to the physical environment, e.g., flora, fauna, and ground and surface waters. Social…

Response to Anti CD20 Monoclonal Antibody Rituximab® and Epitope Mapping of Inhibitory Antibodies in Patients with Acquired Haemophilia.

2006

Abstract Introduction: Acquired haemophilia (AcH) is associated with the development of polyclonal autoantibodies against FVIII, which affect directly the A2 or C2 domain of the FVIII molecule. Immunomodulatory therapy regimes to normalize FVIII levels and to eliminate the inhibitor are essential options in the treatment of patients (pts) with AcH. The aims of the present study were to investigate the response to Rituximab® and to localize the inhibitor epitopes on the FVIII domains. Patients and Methods: In 5 pts with AcH (2 females,3 males; age: 64–81 yrs) the inhibitor titers ranged from 9 to 156 BU and the FVIII activities from <1 % to 6 %. Rituximab® was administered once weekly…

Evolution of Pediatric Migraine Patients Admitted at an Emergency Department after a 10-Year Follow-Up

2023

Background: Despite its high prevalence, the clinical course of pediatric migraine has not been fully understood, and previous studies present conflicting results. We present here the findings of a 10-year follow-up study involving children with severe migraine pain admitted to our emergency department. Furthermore, all studies were carried out on selected outpatient clinical case studies. Our aim was to evaluate a population of migraine children admitted to an emergency department because of increased severity or frequency of pain or even because of very anxious parents concerning their child’s headache in order to describe their long-term outcomes, whether it differed from that of o…

Leisure-time physical activity, weight gain and health : a prospective follow-up in twins

2011

Five-year cumulative exposure to antipsychotic medication after first-episode psychosis and its association with 19-year outcomes

2020

Abstract Background: The long-term effectiveness of antipsychotic maintenance treatment after first-episode psychosis (FEP) is contested. In this real-world observational study, we examined how cumulative exposure to antipsychotics within the first 5 years from FEP was associated with the 19-year outcome. Methods: Finnish national registers were used to detect all patients who were hospitalized due to non-affective psychosis in the mid-1990s, and who were treatment naïve prior to the inclusion period (N = 1318). Generalized linear models with logit link function were used to estimate how cumulative exposure to antipsychotics within the first 5 years from onset was associated with mortality,…