Search results for " Failure"
showing 8 items of 1828 documents
Clinical Behavior of Ceramic, Hybrid and Composite Onlays. A Systematic Review and Meta-Analysis
2020
A systematic review and meta-analysis was performed to analyze the survival of onlay restorations in the posterior region, their clinical behavior according to the material used (ceramic reinforced with lithium disilicate, conventional feldspathic ceramic or reinforced with leucite; hybrid materials and composite), possible complications, and the factors influencing restoration success. The systematic review was based on the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement, without publication date or language restrictions. An electronic search was made in the PubMed, Scopus, Embase, and Cochrane databases. After discarding duplicate publications and stu…
Government policy failure in public support for research and development
2014
peer-reviewed Promoting Research and Development (R&D) and innovative activity is a key element of the EU Lisbon Agenda and is seen as playing a central part in stimulating economic development. In this paper we argue that, even allowing for benevolent policy-makers, informational asymmetries can lead to a misallocation of public support for R&D, hence government policy failure, with the potential to exacerbate preexisting market failures. Initially, we explore alternative allocation mechanisms for public support, which can help to minimize the scale of these government policy failures. Of these mechanisms (grants, tax credits, or allocation rules based on past performance), our results sug…
Fear of failing in a competitive achievement setting : the relations between fear of failure, achievement goals and achievement behaviours among adol…
2017
Tutkimme, miten epäonnistumisen pelko on yhteydessä tavoiteorientaatioihin, pitkäjänteisyyteen, panostamiseen ja viihtymiseen teini-ikäisten poikien jalkapalloharrastuksessa. Olimme lisäksi kiinnostuneita siitä, miten yhteneväisiä pelaajien itsearvioinnit ja heidän valmentajiensa arviot olivat pelaajien pitkäjänteisyyteen, panostamiseen ja viihtymiseen liittyen ja vaikuttiko valmennusaika mahdollisiin näkemyseroihin. Epäonnistumisen pelko on tyypillinen haittailmiö kilpailullisessa toiminnassa, se edeltää usein epäedullisten tavoiteorientaatioiden syntymistä ja on yhteydessä viihtymisen vähenemiseen ja harrastuksen lopettamiseen. Tavoiteorientaatiot kertovat tarkempaa tietoa motivaation laa…
Intravenous iron therapy in patients with heart failure. A double-edged sword
2013
We read with interest the article of Beck-da-Silva et al., who recently concluded that intravenous (IV) iron seems to be superior over oral supplementation for improving functional capacity of heart failure patients [1]. Irrespective of the study design, involving comparison of functional outcomes between two different means of iron supplementation, we raise some clinical issues about the rationale underlying this investigation. According to the data published by Beck-da-Silva et al., the modest number of patients (n = 23) enrolled in this multicenter investigation had moderate anemia (i.e., hemoglobin concentration comprised between 90 and 120 g/L) but no evidence of iron deficiency, which…
Peri-Implant Behavior of Tissue Level Dental Implants with a Convergent Neck
2021
Introduction: The aim of this retrospective study was to analyze the radiographic peri-implant bone loss of bone level implants and tissue level implants with a convergent neck in screw-retained single crowns and in screw-retained fixed partial prostheses, after two years of functional loading. Materials and methods: The sample was divided into two groups according to their type: Group I: supracrestal implants with convergent transmucosal neck
The effect of a failure and submaximal blood flow restriction resistance exercise protocol on changes in muscle size, strength and swelling
2016
Masteroppgave i idrettsvitenskap - Universitetet i Agder 2016 Introduction: Blood flow restricted resistance exercise (BFRRE) can induce rapid increases in muscle size, strength and swelling. No previous research has investigated the importance of conducting BFRRE to voluntary failure and few studies has been carried out to investigate associations between swelling and muscle size. Therefore, the aim of the present study was twofold (1) compare changes in muscle size and strength between a failure (FA) and submaximal (SU) BFRRE protocol (2) investigate associations between swelling and muscle size. Methods: Seventeen untrained men had their legs randomized to FA and SU protocols. The interv…
Apoptosis in human unfertilized oocytes after intracytoplasmic sperm injection
2005
Objective To investigate the presence of programmed cell death in unfertilized oocytes after intracytoplasmic sperm injection (ICSI), assuming that previous apoptotic events could be correlated with the fertilization failure. Design Comparison of the rate of DNA fragmentation in human oocytes at different stages of maturation soon after pick-up (control) and in unfertilized oocytes after ICSI treatment. Setting In vitro fertilization (IVF) laboratory with extensive ICSI experience. Patient(s) Sixty-three patients undergoing assisted fertilization by ICSI. Intervention(s) Terminal deoxynucleotidyl transferase-mediated digoxigenin-dUTP nick-end labeling (TUNEL) assay and anticaspase-3 cleaved…
NT-3 in cardiovascular pathologies
2019
La NT-3 y su receptor TrkC son puntos clave en la formación del corazón y los vasos durante la etapa embrionaria. Sin embargo, el papel de la NT-3 como modulador de las funciones cardiovasculares en la edad adulta no ha sido investigado con detalle. El objetivo de la presente Tesis es determinar la expresión de NT-3 y TrkC en el sistema cardiovascular humano y de roedores, así como el papel de la vía NT-3/TrkC como moduladora de las funciones cardiovasculares y su relación con las enfermedades a este nivel. Para ello, se cuantificó la expresión génica y proteica de NT-3 y TrkC, en tejidos humanos y de roedores, así como en células humanas cardiacas y aorticas. Los resultados muestran que lo…