Search results for " Farm"

showing 10 items of 2009 documents

Conservation value of forest plantations for bird communities in western Kenya

2008

Tree plantations of native and exotic species are frequently used to compensate for forest loss in the tropics. However, these plantations may support lower species diversity and different communities than natural forest. We therefore investigated bird communities in stands of natural forest, different types of tree plantations and secondary forest in Kakamega Forest, western Kenya. We compared birds differing in habitat specialisation, i.e. forest specialists, generalists, and visitors. We recorded significant differences in mean species richness and number of individuals among the different forest types. Stands of natural forest and plantations of indigenous tree species comprised more sp…

geographygeography.geographical_feature_categoryAgroforestryForest managementForestryManagement Monitoring Policy and LawBiologyOld-growth forestForest restorationForest ecologySecondary forestSpecies richnessForest farmingIntact forest landscapeNature and Landscape ConservationForest Ecology and Management
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High seedling recruitment of indigenous tree species in forest plantations in Kakamega Forest, western Kenya

2009

Tree plantations are often used to compensate for the destruction and conversion of natural forests in the tropics. An important question is whether these plantations allow for the regeneration of indigenous tree species and are expected to transform into more natural forests in the future. To evaluate the potential of differently managed forest types for seedling recruitment of indigenous tree species we studied structural characteristics as well as tree and seedling communities in stands of natural forest, different types of tree plantations and secondary forest in Kakamega Forest, western Kenya. Forest types differed considerably in structural characteristics and tree composition with st…

geographygeography.geographical_feature_categoryAgroforestryForest managementForestryManagement Monitoring Policy and LawBiologyOld-growth forestForest restorationForest ecologySecondary forestSpecies richnessForest farmingNature and Landscape ConservationTropical rainforestForest Ecology and Management
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COVID-19 Pandemic: New Prevention and Protection Measures

2022

As of the end of February 2021, more than 420,000,000 confirmed cases of COVID-19 have been reported worldwide, with 5,856,224 deaths. Transmission of the different genetically engineered variants of SARS-CoV-2, which have been isolated since the beginning of the pandemic, occurs from one infected person to another by the same means: the airborne route, indirect contact, and occasionally the fecal–oral route. Infection is asymptomatic or may present with flulike symptoms such as fever, cough, and mild to moderate and severe respiratory distress, requiring hospitalization and assisted ventilation support. To control the spread of COVID-19, the World Health Organization (WHO) and Centers for …

glovesRenewable Energy Sustainability and the EnvironmentSARS-CoV-2pandemicoccupational medicineSettore MED/44 - Medicina Del LavoroGeography Planning and DevelopmentCOVID-19organizational measureManagement Monitoring Policy and LawprotectioninfectioncoronavirumaskworkpreventionSettore MED/43 - Medicina LegaleSettore BIO/14 - FarmacologiaPPEprotocolenvironmental measure
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Drug release from α,β-poly(N-2-hydroxyethyl)-DL-aspartamide based microparticles

2004

Spherical pH-sensitive microparticles have been prepared by reverse phase suspension polymerization technique. Starting polymer has been alpha,beta-poly(N-2-hydroxyethyl)-dl-aspartamide (PHEA) partially derivatized with glycidylmethacrylate (GMA). PHEAGMA copolymer (PHG) has been crosslinked in the presence of acrylic acid (AA) or methacrylic acid (MA) at various concentration. The obtained microparticles have been characterized by FT-IR spectrophotometry, particle size distribution analysis and scanning electron microscopy. In order to have information about water affinity of the prepared samples, swelling measurements have been carried out in aqueous media which simulate some biological f…

glycidylmethacrylateSettore CHIM/09 - Farmaceutico Tecnologico Applicativoradical crosslinking pH-sensitive hydrogeldrug release
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HSV-1 Glycoprotein D and Its Surface Receptors: Evaluation of Protein–Protein Interaction and Targeting by Triazole-Based Compounds through In Silico…

2023

Protein–protein interactions (PPI) represent attractive targets for drug design. Thus, aiming at a deeper insight into the HSV-1 envelope glycoprotein D (gD), protein–protein docking and dynamic simulations of gD-HVEM and gD-Nectin-1 complexes were performed. The most stable complexes and the pivotal key residues useful for gD to anchor human receptors were identified and used as starting points for a structure-based virtual screening on a library of both synthetic and designed 1,2,3-triazole-based compounds. Their binding properties versus gD interface with HVEM and Nectin-1 along with their structure-activity relationships (SARs) were evaluated. Four [1,2,3]triazolo[4,5-b]pyridines were i…

glycoprotein DOrganic Chemistrymolecular dynamics simulationsGeneral MedicineHSV-1Settore CHIM/08 - Chimica FarmaceuticaCatalysisComputer Science ApplicationsInorganic Chemistryprotein–protein interactionprotein–protein interaction; HSV-1; 123-triazoles; docking; molecular dynamics simulations; glycoprotein Ddocking123-triazolesPhysical and Theoretical ChemistryMolecular BiologySpectroscopyInternational Journal of Molecular Sciences
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COUPLING ELECTROCHEMISTRY TO ELECTROSPRAY: A NOVEL PREPARATION OF GOLD NANOSTRUCTURES

2013

nanoparticles on ITO (Indium tin oxide) coated glass using the electrospray (ESI) method Method:The starting point of this study is that the ESI/MS spectrum (Figure 1) of an ethanolic solution of HAuCl 4 shows a reduction process of Au (III) strongly dependent on the Cone Voltage (CV) values (20, 80, 150 V), affording to the ion at m/z 197 (Au+). Further, the decrease of the abundance of this ion at the highest cone voltage suggests the subsequent its reduction with the formation of Au 0 . Figure 1: ESI/MS spectra of an ethanolic solution of HAuCl4 at various cone voltages: Conclusion: Such experimental evidence leads us to use electrospray technique as a preparative tool to obtain the form…

gold nanoparticles electrospray S.E.M.Settore CHIM/01 - Chimica AnaliticaSettore CHIM/08 - Chimica FarmaceuticaSettore CHIM/02 - Chimica Fisica
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Possible mechanisms of Raf-1 Kinase Inhibitor Protein down-regulation in hepatocellular carcinoma

2011

hepatocellular carcinoma HDACi epigenetic changes.RKIP (Raf-1 Kinase Inhibitor Protein)Settore BIO/14 - Farmacologia
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Induction of Apoptosis and Chemosensitization by the Histone Deacetylase Inhibitor Trichostatin in Hepatocellular Carcinoma Cells: Molecular Analysis…

2011

The mRNA and protein levels of RKIP are reduced and those of YY1 increased in clinical HCC. Loss, mutation, or promoter hypermethylation of the RKIP gene may not account for the downregulation of RKIP in HCC. Histone deacetylation can silence gene expression and play a significant role in hepatocarcinogenesis. The histone deacetylase inhibitor (HDACI) trichostatin induced cell growth inhibition and proapoptotic effects in HA22T/VGH and HepG2 HCC cells; it also exhibited synergy with doxorubicin. Treatment with trichostatin caused histone hyperacetylation and down- or upregulated expression of different genes (such as β-catenin, cyclin D1, hTERT, XIAP, and IL-6). These changes might, at leas…

hepatocellular carcinoma Raf-1 kinase inhibitor protein Yin Yang 1 gene expression histone deacetylase inhibitor trichostatin apoptosis chemosensitizationHistone deacetylase 5medicine.drug_classChemistryHDAC11Histone deacetylase inhibitormedicine.diseaseBiochemistryMolecular biologyMolecular analysisApoptosisChemosensitizationHepatocellular carcinomaGene expressionGeneticsmedicineCancer researchSettore BIO/14 - FarmacologiaMolecular MedicineBiotechnology
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Editorial: Emerging heterocycles as bioactive compounds

2023

Heterocycles represent a privileged scaffold due to their ability to interact with biological systems via heteroatoms. It is no coincidence that every year the Food and Drug Administration approves numerous new drugs that contain at least one heterocyclic system as active pharmacophoric part in their structure. Many heterocyclic compounds with therapeutic properties, including anticancer, antimicrobial, anti-inflammatory and so on, come from natural sources such as plants and animals, and medicinal chemists very often use them to study their chemical space and improve their biological activity. In fact, several efficient approaches for the formation of aromatic heterocyclic compounds and th…

heterocycles new chemical entities natural products purine nucleoside phosphorylase pantetheinase sulfhydrylase activity quinazolineGeneral ChemistrySettore CHIM/08 - Chimica FarmaceuticaFrontiers in Chemistry
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The Role of 1,3-Dipolar Cycloaddition Reactions in the Design and Synthesis of Complex Heterocyclic Scaffolds with Anti-tumor/Anti-infective Activity

2009

heterocyclic scaffoldanti-infective activity13-dipolar cycloaddition reactionanti-tumor activitySettore CHIM/08 - Chimica Farmaceutica
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