Search results for " Farm"

Synthesis and biological evaluation of some new 2-phenylpropiolamidobenzamides as potential antagonists of the HMDM2-p53 protein-protein interactions

2009

Study on the mechanism of action of antitumor photochemotherapic agents by means of docking and QSPR analysis

2008

Modulation of Efficient Diiodo-BODIPY in vitro Phototoxicity to Cancer Cells by Carbon Nano-Onions

2020

Photodynamic therapy (PDT) is currently one of the most promising approaches for targeted cancer treatment. It is based on responses of vital physiological signals, namely reactive oxygen species (ROS), which are associated with diseased condition development, such as tumors. This study presents the synthesis, incorporation, and application of a diiodo-BODIPY based photosensitizer, based on a non-covalent functionalization of carbon nano-onions (CNOs). In vitro assays demonstrate that HeLa cells internalize the diiodo-BODIPY molecules, and their CNOs nanohybrids. Upon cell internalization and light exposure, the pyrene-diiodo-BODIPY molecules induce an increase of the ROS level of HeLa cell…

Phytol and Heptacosane Are Possible Tools to Overcome Multidrug Resistance in an In Vitro Model of Acute Myeloid Leukemia

2022

Drug resistance is the ability of cancer cells to gain resistance to both conventional and novel chemotherapy agents, and remains a major problem in cancer therapy. Resistance mechanisms are multifactorial and involve more strictly pharmacological factors, such as P-glycoprotein (P-gp) and biological factors such as inhibitor of apoptosis proteins (IAPs) and the nuclear factor-kappa B (NF-κB) pathway. Possible therapeutic strategies for the treatment of acute myeloid leukemia (AML) have increased in recent years; however, drug resistance remains a problem for most pa-tients. Phytol and heptacosane are the major compounds of Euphorbia intisy essential oil (EO) which were demonstrated to inhi…

The management of crop-livestock systems at a territory level: the example of grain legume crops and of monogastric livestock in Burgundy, France

2012

Although cereals and oil seed crops are very developed in Burgundy, the area of grain legumes cultivation is small. Concerning monogastric livestock, the region is characterised by a medium size poultry production focussed on markets under quality and origin signs (SIQO) and a relatively small pig production. Although a tendency of co-location of these productions can be observed (at territory and farm scales) and some animals consume locally-produced proteins, there is no strong functional link between these crops and animal activities. This situation is confirmed by the fact that a significant proportion of produced grain legumes are exported by Burgundy, while large quantities of soybean…

Sintesi e studi SAR di nuovi derivati 4-NO- e (4-ONNCN)-pirazolici

2011

Technical English for agriculture

2021

As the world goes global, the agricultural business needs to move across frontiers and oceans. Food, raw and processed, is regularly transported across continents. As space is no longer a limit for food trade and human nutrition, language cannot represent a barrier to this continuous exchange. In the last 60 years, English has been taking a foothold as the primary language for world trade and the exchange of agricultural goods is no exception. Agricultural sciences embrace a large number of disciplines, from botany to environmental physiology, from soil science to meteorology, from plant propagation to cultural management, from soil management to pest control, from field crops to animal husb…

Characterization of Erwinia gerundensis A4, an Almond-Derived Plant Growth-Promoting Endophyte

2021

The rapidly increasing global population and anthropogenic climate change have created intense pressure on agricultural systems to produce increasingly more food under steadily challenging environmental conditions. Simultaneously, industrial agriculture is negatively affecting natural and agricultural ecosystems because of intensive irrigation and fertilization to fully utilize the potential of high-yielding cultivars. Growth-promoting microbes that increase stress tolerance and crop yield could be a useful tool for helping mitigate these problems. We investigated if commercially grown almonds might be a resource for plant colonizing bacteria with growth promotional traits that could be use…

Effetti biologici del polifenoli dell'olio extravergine di oliva di cultivar nazionali su cellule tumorali umane sensibili e resistenti ai farmaci an…

2012

Improvements in Rational Design Strategies of Inulin Derivative Polycation for siRNA Delivery.

2016

The advances of short interfering RNA (siRNA)-mediated therapy provide a powerful option for the treatment of many diseases, including cancer, by silencing the expression of targeted genes involved in the progression of the pathology. On this regard, a new pH-responsive polycation derived from inulin, Inulin-g-imidazole-g-diethylenetriamine (INU-IMI-DETA), was designed and employed to produce INU-IMI-DETA/siRNA "Inulin COmplex Nanoaggregates" (ICONs). The experimental results showed that INU-IMI-DETA exhibited strong cationic characteristics and high solubility in the pH range 3-5 and self-aggregation triggered by pH increase and physiological salt concentration. INU-IMI-DETA showed as well…